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Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.

14 Nov 2023

Understanding factors influencing PrEP prescribing for adolescents

HIV pre-exposure prophylaxis (PrEP), a daily dose of two medications meant to prevent HIV infection in high-risk people, has changed public health dramatically in recent years.

14 Nov 2023

Do Republican spending cuts threaten federal HIV funding? For some programs, yes.

Republicans in Congress are "trying to wipe out federal funding to end the HIV epidemic."

14 Nov 2023

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Intratumoral therapy – in which cancer drugs are injected directly into tumors – is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection.

13 Nov 2023

Novel assay may improve detection and treatment of acute myeloid leukemia

A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML) may revolutionize the way this disease is detected and treated according to a new report in The Journal of Molecular Diagnostics published by Elsevier.

13 Nov 2023

AI-based model can predict therapy outcome in ovarian cancer patients

A model based on artificial intelligence is able to predict the therapy outcome (measured by volumetric reduction of tumor lesions) in 80% of ovarian cancer patients.

13 Nov 2023

CÚRAM researchers make breakthrough in cell visualization

CÚRAM researchers at University of Galway, together with colleagues at the Centre for Molecular Nanometrology at University of Strathclyde have published work unveiling the inner workings of cells.

10 Nov 2023

Physical fitness during childhood impacts cerebellar structure in adolescence

Physical fitness since childhood is associated with cerebellar grey matter volume in adolescents.

10 Nov 2023

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Andrew Buchanan on the Future of Biologics and AI

10 Nov 2023

Left-handedness is not linked to better spatial skills, study shows

It's been debated for decades, but now researchers at the University of York and University College London have suggested that left-handedness is not linked to better spatial skills.

9 Nov 2023

A new RSV shot could help protect babies this winter — if they can get it in time

Emily Bendt was in her third trimester of pregnancy when she first heard the Centers for Disease Control and Prevention had approved a new shot for infants to protect them from the respiratory syncytial virus, or RSV.

9 Nov 2023

12-week daily strawberry intake improves brain health among middle-aged, overweight adults

A new study published in Nutrients shows daily consumption of strawberries for 12 weeks reduced interference in memory and depressive symptoms among middle-aged, overweight adults with self-reported mild cognitive decline.

8 Nov 2023

Anesthetic drug propofol cancels sensory processing by cutting it off communication within the cortex

General anesthesia evokes a dual mystery: How does it disrupt consciousness, including sensory perception, and what might that say about the nature of consciousness.

8 Nov 2023

US to cover HIV prevention drugs for older Americans to stem spread of the virus

A proposed federal policy aims to protect older Americans from contracting HIV by offering free preventive medication, the latest effort to catch up to much of Europe and Africa in stemming the spread of the virus.

8 Nov 2023

Suspected bronchiectasis linked to increased mortality in smokers

Bronchiectasis, a condition defined by widened lung airways, cough and sputum production, and frequent infections, often presents along with chronic obstructive pulmonary disease (COPD). This overlap is associated with airflow obstruction and higher mortality in adults.

7 Nov 2023

PET scans of the heart identify people at risk for Parkinson's and Lewy body dementia

In a small study, researchers at the National Institutes of Health have found that positron emission tomography (PET) scans of the heart may identify people who will go on to develop Parkinson's disease or Lewy body dementia among those at-risk for these diseases.

7 Nov 2023

Climate change could exacerbate respiratory disease deaths during warm seasons

Global warming caused by climate change could exacerbate the burden of inpatient mortality from respiratory diseases during the warm season.

7 Nov 2023

Unraveling the role of HER2 mutant alleles in breast cancer

A new editorial paper was published in Oncotarget's Volume 14 on October 31, 2023, entitled, "The uncharted role of HER2 mutant alleles in breast cancer."

6 Nov 2023

Pregnant women in blighted neighborhoods have higher testosterone levels, study finds

Pregnant women living in blighted neighborhoods with high levels of known stressors have higher levels of testosterone – the primary sex hormone in males -- which disrupt hormone regulation and may lead to life-threatening complications during and after childbirth, according to Rutgers research.

3 Nov 2023

New pathway to combat cardiovascular disease identified

Research led by the University of Minnesota Medical School identified a new pathway to combat cardiovascular disease. The study was recently published in Nature Cardiovascular Research.

3 Nov 2023

OCT News and Research

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Understanding factors influencing PrEP prescribing for adolescents

Do Republican spending cuts threaten federal HIV funding? For some programs, yes.

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Novel assay may improve detection and treatment of acute myeloid leukemia

AI-based model can predict therapy outcome in ovarian cancer patients

CÚRAM researchers make breakthrough in cell visualization

Physical fitness during childhood impacts cerebellar structure in adolescence

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Left-handedness is not linked to better spatial skills, study shows

A new RSV shot could help protect babies this winter — if they can get it in time

12-week daily strawberry intake improves brain health among middle-aged, overweight adults

Anesthetic drug propofol cancels sensory processing by cutting it off communication within the cortex

US to cover HIV prevention drugs for older Americans to stem spread of the virus

Suspected bronchiectasis linked to increased mortality in smokers

PET scans of the heart identify people at risk for Parkinson's and Lewy body dementia

Climate change could exacerbate respiratory disease deaths during warm seasons

Unraveling the role of HER2 mutant alleles in breast cancer

Pregnant women in blighted neighborhoods have higher testosterone levels, study finds

New pathway to combat cardiovascular disease identified

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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