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Air pollution linked with development of Alzheimer's in Mexico City children

A new study by researchers at the Universities of Montana, Valle de México, Boise State, Universidad Veracruzana, Instituto Nacional de Pediatría and Paul-Flechsig-Institute for Brain Research heightens together with German company Analytik Jena concerns over the evolving and relentless Alzheimer's pathology observed in young Metropolitan Mexico City urbanites.

21 Dec 2018

Inflating cells to analyze organelle structure and function

Researchers have developed a technique that enables visualization of cellular organelles at a resolution that has not previously been achievable in optical microscopy.

17 Dec 2018

Researchers develop new technique to accurately isolate phloem cells across plants

Crops worldwide are increasingly vulnerable to pandemics, as diseases hitch rides on global flows of people and goods, hopping from continent to continent. Phloem diseases such as citrus greening are one particularly devastating group of plant diseases that have been wreaking economic havoc globally.

4 Dec 2018

New study solves longstanding mystery in innate immunity

UT Southwestern biochemist and Breakthrough Prize winner Dr. Zhijian "James" Chen's newest study answers a long-standing question in the field of innate immunity.

29 Nov 2018

Researchers discover how mitochondria deploy a powerful punch against disease-causing bacteria

The constant battle for dominance between disease-causing bacteria and our immune systems has led to the evolution of some crafty warfare tactics on both sides.

12 Nov 2018

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

A genetic defect tied to a variety of neurodegenerative diseases and mental illnesses changes how cells starved of sugar metabolize fatty compounds known as lipids, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health shows.

31 Oct 2018

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic code with the cognate amino acid, which are the building blocks of proteins.

19 Oct 2018

New chemo-optogenetic method enables multi-directional activity control of cellular processes

Cells need for reactions on environmental changes and a balanced system of signaling cascades within the cell. Proteins outside of the cell, on the cellular surface, inside the cellular membrane, and within the cell orchestrate many fine-tuned signaling pathways, which result in adequate reactions on the environmental conditions or changes in the organism itself.

19 Sep 2018

Researchers report how Zika proteins hijack host cells

Most people infected with Zika never show symptoms. But the virus sometimes causes severe disability -- from microcephaly in babies to weakness or partial paralysis in adults -- and there is no treatment.

28 Aug 2018

New insight could help develop novel and more effective antidepressant drugs

A new area in depression research suggests dysfunction in mitochondria -- the main source of energy for cells -- could lead to major depression.

10 Aug 2018

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Regenacy Pharmaceuticals, LLC, a clinical-stage biopharmaceutical company developing breakthrough treatments for diabetic and other peripheral neuropathies, today announced a collaboration with the Charcot-Marie-Tooth Association, a registered non-profit organization serving the hereditary neuropathy patient community, to validate the role of HDAC6 in multiple forms of Charcot-Marie-Tooth disease and evaluate the efficacy of ricolinostat, a selective HDAC6 inhibitor, in animal models.

2 Aug 2018

Researchers describe strategy used by Oropouche virus to replicate in human cells

The strategy used by the Oropouche virus to replicate in human cells has been described for the first time by researchers at the University of São Paulo in Brazil and international collaborators in an article published in the journal PLOS Pathogens.

31 Jul 2018

Researchers develop near-infrared fluorophores-based PDT to cure cancer with less side effects

A KAIST research team developed near-infrared fluorophores-based photodynamic therapy that reduced the downside of existing PDTs.

16 Jul 2018

Research sheds on how new species may arise from rapid mitochondrial evolution

Genetic research at Oregon State University has shed new light on how isolated populations of the same species evolve toward reproductive incompatibility and thus become separate species.

13 Jul 2018

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells.

25 Jun 2018

Study: Inner nuclear envelope plays role in lipid metabolism

The cell nucleus is an organelle, in which the DNA of an organism is protected and duplicated. The nucleus of this organ-like structure in the cell plasma is surrounded by an outer and an inner nuclear envelope, which is penetrated by openings - so-called nuclear pores.

22 Jun 2018

New studies on fat cell filling, history of biochemistry, and ketogenic diet

There's more than one type of fat cell. Besides the white fat that stores triglycerides in lipid droplets in preparation for lean times later, mammals also have heat-generating brown fat, which acts more like a radiator than a storage closet.

14 Jun 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

Study identifies critical role of protein in sperm tail development

The group led by ICREA Research Professor Cayetano Gonzalez at the Institute for Research in Biomedicine, in collaboration with Giuliano Callaini's team at the University of Siena in Italy, has published a study in The Journal of Cell Biology that identifies the critical role played by a protein called CENTROBIN in sperm tail development.

11 May 2018

New studies use proteomics to shed light on pathogenic mechanisms

Recent studies in the journal Molecular & Cellular Proteomics have shed light on pathogenic mechanisms of the sexually-transmitted parasite Trichomonas vaginalis and the HIV-associated opportunistic lung fungus Aspergillus.