Organelle News and Research

RSS

Osmium-based compound seen to target cancer cells from inside

Researchers have witnessed - for the first time - cancer cells being targeted and destroyed from the inside, by an organo-metal compound discovered by the University of Warwick.

13 Feb 2017

Research uncovers previously unknown mechanism that could be key to alternative lupus treatment

Only one new drug has become available over the past 50 years for the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus, but new research has identified a previously unknown mechanism involved in the immune response that could provide an alternative therapy target.

10 Feb 2017

VIB-KU Leuven researchers identify underlying mechanism in early onset Parkinson's disease

A team of researchers led by Patrik Verstreken have identified an underlying mechanism in early onset Parkinson's.

10 Feb 2017

Exeter scientists discover how two cell organelles interact at molecular level

Scientists have made a breakthrough in understanding how different compartments (or organelles) of human cells interact.

20 Jan 2017

Blocking molecular signaling pathway could prevent or reverse peripheral neuropathy

Researchers at University of California San Diego School of Medicine, with colleagues at the National Institute of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy-induced neuropathy and HIV.

18 Jan 2017

Study provides insights into CPEB4 gene and fatty liver disease

This condition generally leads to chronic inflammation (non-alcoholic steatohepatitis), which can trigger fibrosis, cirrhosis and ultimately liver cancer. This study on the basic biology of the liver paves the way to examine therapeutic strategies to fight and prevent fatty liver disease.

18 Jan 2017

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

UT Southwestern Medical Center researchers have identified a protein that is central to the immune system's ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.

12 Jan 2017

Study strengthens therapeutic potential for niacin-based diet in treatment of Parkinson's disease

People with certain forms of early-onset Parkinson's disease may benefit from boosting the amount of niacin in their diet, according to new research from the University of Leicester.

11 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

New tool explains how proteins assemble into different liquid and gel-like solid states

A tool that uses light to manipulate matter inside living cells has begun to explain how proteins assemble into different liquid and gel-like solid states, a key to understanding many critical cellular operations.

30 Dec 2016

Super-resolution fluorescence microscopy sheds light on brain’s molecular mechanism

Advances in microscopy techniques have often triggered important discoveries in the field of neuroscience, enabling vital insights in understanding the brain and promising new treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's.

29 Dec 2016

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans.

22 Dec 2016

New study reveals IRBIT's role in facilitating apoptosis

Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary for apoptosis to occur properly.

21 Dec 2016

Mayo Clinic scientists show how hungry liver cells find energy

In a recent Science Advances article, Mayo Clinic researchers show how hungry human liver cells find energy.

20 Dec 2016

NIH-funded scientists work with three ‘omes’ to understand human health

Have you ever collected coins, cards, toy trains, stuffed animals? Did you feel the need to complete the set? If so, then you may be a completist. A completist will go to great lengths to acquire a complete set of something.

17 Dec 2016

TMDU researchers identify novel type of cell death in Huntington's disease

In Huntington's disease (HD), the huntingtin gene is mutated, causing progressive neuronal death.

22 Nov 2016

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle.

17 Nov 2016

Discovery of novel protein could lead to potential new treatments for age-related retinal disease

The discovery of a novel protein that links aging and age-dependent retinal diseases could lead to potential new treatments for conditions that cause sight loss in later life.

15 Nov 2016

Researchers propose model photomotors for rapid nanoparticle transport

Scientists from the Moscow Institute of Physics and Technology, Semenov Institute of Chemical Physics of the Russian Academy of Sciences, and Chuiko Institute of Surface Chemistry of the National Academy of Sciences of Ukraine have proposed a model nanosized dipole photomotor based on the phenomenon of light-induced charge redistribution.

11 Nov 2016

Cannabinoid receptors regulate memory processes by modulating mitochondrial energy metabolism

It has been known for some time that the extracts of the Cannabis plant, just like synthetic cannabinoids and those produced by the brain itself, join up with type 1 (CB1) cannabinoid receptors located in the nerve endings of the neurons, and inhibit the release of chemical messengers (neurotransmitters) in the communication areas between the nerve cells.

10 Nov 2016