Organic chemistry News and Research

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Scientists create artificial protein that mimics key site on the outer coat of HIV

A team of scientists at Duke Medicine and Memorial Sloan-Kettering Cancer Center has created an artificial protein coupled with a sugar molecule that mimics a key site on the outer coat of HIV where antibodies can bind to neutralize a wide variety of HIV strains.

23 Oct 2013

New method to display viral DNA in host cells at single-molecule resolution

The medical, humanitarian and economical impact of viral diseases is devastating to humans and livestock. There are no adequate therapies available against most viral diseases, largely because the mechanisms by which viruses infect cells are poorly known.

17 Oct 2013

TSRI scientists find new way to boost effectiveness of anticancer drugs

Scientists at The Scripps Research Institute (TSRI) have found a way to make dramatic improvements to the cancer cell-killing power of vinblastine, one of the most successful chemotherapy drugs of the past few decades.

17 Sep 2013

Flecainide, encainide drugs increase risk of sudden cardiac death

Scientists have discovered that a drug which increases the risk of sudden cardiac death interacts with mistranslated protein-coding genes present in heart muscle.

17 Sep 2013

Scientists develop antibiotic whose activity can be controlled using light

Scientists at the University of Groningen have developed an antibiotic whose activity can be controlled using light. It is possible to 'switch on' the substance immediately before use, after which it will slowly lose its activity.

16 Sep 2013

New catalyst class uses halogen bridges for environmentally friendlier production

Ninety percent of all chemical products require catalysts in the course of their manufacture. They accelerate reactions and reduce the energy needed. Catalysts participate in reactions, but are not consumed. As a result one catalyst molecule can convert millions of substrate molecules, which explains the great economic value of catalysts.

13 Sep 2013

Professors receive 100,000 Euro from Hartwig Piepenbrock-DZNE for outstanding brain research

The prize is awarded by the Piepenbrock Group and the German Center for Neurodegenerative Diseases (DZNE). The award ceremony will be held in Berlin on September 24, 2013.

12 Sep 2013

New advances toward making molecular prosthetics a reality

The vision for a new branch of medicine, inspired by the ancient field that began with peg legs and hand hooks, commanded the spotlight in a major address by its pioneer here today at the 246th National Meeting & Exposition of the American Chemical Society, the world’s largest scientific society.

11 Sep 2013

Combating antibiotic resistance: an interview with Ron Najafi, CEO NovaBay Pharmaceuticals

Approximately 80 years ago the first antibiotic was discovered by Sir Alexander Fleming, for which he was justifiably awarded the Nobel Prize in medicine.

2 Aug 2013

Scientists to explore student-driven research model for Distributed Drug Discovery

Purdue University Indianapolis (IUPUI) will host scientists from around the world next week for the first-ever workshop devoted to Distributed Drug Discovery, an innovative, student-driven research program quickly becoming a high-impact, low-cost teaching model.

20 Jul 2013

UC professor receives Biemann Medal from ASMS for significant achievement in mass spectrometry

Yinsheng Wang, a professor of chemistry at the University of California, Riverside, has received the Biemann Medal, awarded by the American Society for Mass Spectrometry (ASMS) to an individual early in his or her career in recognition of significant achievement in basic or applied mass spectrometry.

26 Jun 2013

Newly developed approach could benefit basic medical research and help detect H2S in environment

University of Oregon chemists have developed a selective probe that detects hydrogen sulfide (H2S) levels as low as 190 nanomolar (10 parts per billion) in biological samples.

25 Jun 2013

Nanoparticle-based immunotherapy for cancer

The German Research Foundation has established a new Collaborative Research Center on "Nanodimensional polymer therapeutics for tumor therapy" (CRC 1066) at Johannes Gutenberg University Mainz and the Max Planck Institute for Polymer Research (MPI-P).

1 Jun 2013

DFG selects researchers to receive the 2013 Heinz Maier-Leibnitz Prize

This year's recipients of the most important prize for early career researchers in Germany have been announced. The selection committee appointed by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) and the German Federal Ministry of Education and Research (BMBF) have chosen nine researchers, four women and five men, to receive the 2013 Heinz Maier-Leibnitz Prize.

8 May 2013

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body.

7 May 2013

Protein C4BP is possibly suitable as transporter for drugs, say researchers

The protein C4BP is similar to a spider in its spatial form with eight "arms". The structure of the "spider body" has recently been described in detail by researchers from the Helmholtz Centre for Infection Research in Braunschweig and the Technische Universit-t Darmstadt.

29 Apr 2013

Nine Nobel laureates to present their research at American Chemical Society meeting

At least nine Nobel laureates have research that will be presented here this week during the 245th National Meeting & Exposition of the American Chemical Society, the world's largest scientific society.

8 Apr 2013

Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

ADCs are used for a new type of targeted therapy that consists of a specific anti-cancer antibody or antibody fragment linked to a potent anti-cancer therapeutic.

20 Feb 2013

Finding medical applications for unused inventions: an interview with Gabriel Mecklenburg, Co-Founder of Marblar

Marblar is gamifying the process of technology transfer. We post technology on our platform in the form of a challenge, and the Marblar community then competes to uncover new problems these technologies could solve – thereby discovering new market applications for these technologies.

31 Jan 2013

New information on insulin and cell bonding mechanics

The discovery of insulin nearly a century ago changed diabetes from a death sentence to a chronic disease. Today a team that includes researchers from Case Western Reserve University School of Medicine announced a discovery that could lead to dramatic improvements in the lives of people managing diabetes.

11 Jan 2013