Organic chemistry News and Research

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DNA sequencing pioneer, two pharmaceutical researchers recognized as ACS 'Heroes of Chemistry'

Two scientists developed a new drug that helped pioneer the era of "personalized medicine" for cancer patients, an approach in which one-size-fits-all drugs yield to medicines customized to the genetic endowment of individual patients. Another scientist invented today's predominant technology for genetic sequencing, deciphering the genetic blueprint in the DNA that makes up the genes of living things.

30 Aug 2011

Targeted therapies that attack stem cell-like cancer cells can prevent spread of prostate cancer

A successful interdisciplinary project is underway between two research groups, in which senior researcher Rebecka Hellsten and Professor Anders Bjartell at the Faculty of Medicine's division for Urological Cancer Research, Sk-ne University Hospital in Malm-, and Professor Olov Sterner and Assistant Professor Martin Johansson at the Lund University division of Organic Chemistry recently published their latest research findings in the scientific online journal PLoS ONE.

12 Aug 2011

Researchers to develop new prostate cancer therapy

Prostate cancer that has become resistant to hormone treatment and that does not respond to radiation or chemotherapy requires new methods of treatment. By attacking stem cell-like cells in prostate cancer, researchers at Lund University are working on a project to develop a new treatment option.

12 Aug 2011

New nanotechnology-based cancer treatment might improve chemotherapy

Researchers of the University of Granada and Edinburgh have developed a new therapy for cancer based on nanotechnology that might improve significantly chemotherapy, as it has not cause side effects.

19 Jul 2011

Researchers detect 'dechlorane plus' in peregrine falcon eggs

Flame retardants are chemical compounds added to fabrics and plastics to keep them from burning easily, but these can be toxic.

19 Apr 2011

OSU chemist developing solution to nerve agent exposure

Scientists are working to develop a new drug that will regenerate a critical enzyme in the human body that “ages” after a person is exposed to deadly chemical warfare agents.

5 Apr 2011

Tocopherol derivatives as new dioxin receptor antagonists

When reactive oxygen species (ROS) hit the body, vitamin E helps to prevent damage to tissues and cells by acting as an antioxidant. The health benefits of vitamin E are numerous, and in fact, studies have found that people with higher levels of vitamin E in their system have a lower risk of heart disease and certain forms of cancer. A team led by Thomas Rosenau from the University of Natural Resources and Life Sciences in Vienna (Austria) now describe their synthesis of a series of modified vitamin E derivatives that show promise as dioxin receptor antagonists in the European Journal of Organic Chemistry.

18 Mar 2011

American Botanical Council honors excellence in herbal medicine

The 6th Annual American Botanical Council Celebration and Awards Ceremony took place last night, honoring individuals and companies who influence the present and future of the herbal medicine movement. The ABC event is part of the annual Natural Products Expo West trade show and Nutracon scientific conference, held in Anaheim, California.

11 Mar 2011

University of Delaware to host scholarly symposium in honor of Richard F. Heck

On Thursday, May 26, the University of Delaware will host the scholarly symposium "Frontiers in Catalysis" in honor of Richard F. Heck, Willis F. Harrington Professor Emeritus of Chemistry and Biochemistry, and winner of the 2010 Nobel Prize in Chemistry.

5 Mar 2011

Biochemist receives STAC grant to find treatment for C. albicans infection in premature infants

A $200,000 grant from the Rhode Island Science and Technology Advisory Council is helping a Bryant University biochemist find a treatment for a fungal infection that is often lethal to premature infants.

23 Feb 2011

Scientists produce tiny molecular 'binder' that may help develop more efficient drugs

Developing new drugs is a highly costly and time-consuming process. Of 20 candidates, 19 are normally rejected because they don't work or have unwanted side effects. Now a research team led by Professor Lars Baltzer at Uppsala University has produced a tiny molecular "binder" that has the potential to change this landscape radically.

19 Jan 2011

Innovative method for in-cell gene manipulation

A cross-disciplinary Small Medicine and Advanced Research Translation (SMART) team led by Prof. Dar-Bin Shieh of Institute of Oral Medicine in Medical College at National Cheng Kung University (NCKU), Tainan, Taiwan, has announced a breakthrough in the precision in-cell gene scission at pre-designed sequence sites using Artificial Targeting Light Activated Nano Scissors (ATLANS) and a custom build photonic device.

9 Nov 2010

New solvent system could provide ways of producing nanometer-scale cancer chemotherapy agents

Noble metals such as platinum and palladium are becoming increasingly important because of growth in environmentally friendly applications such as fuel cells and pollution control catalysts. But the world has limited quantities of these materials, meaning manufacturers will have to rely on efficient recycling processes to help meet the demand.

29 Oct 2010

SAFC expands fermentation capabilities in Israel facility

SAFC, a member of the Sigma-Aldrich® Group (Nasdaq: SIAL), today announced the completion of its state-of-the-art expansion of its Jerusalem, Israel facility. The additional capacity expands SAFC's contract manufacturing capabilities in large molecule recombinant proteins and small molecule Active Pharmaceutical Ingredients (APIs) through fermentation, including High Potent APIs (HPAPIs) and secondary metabolites.

6 Oct 2010

Ensemble Therapeutics showcases data on new drug discovery platform at ACS National Meeting

Ensemble Therapeutics announced today the presentation of data on its macrocyclic-based drug discovery platform at the American Chemical Society National Meeting August 22-26, in Boston at the Boston Convention and Exposition Center.

24 Aug 2010

HuMed program at Mount Sinai provides various educational experiences before medical school

Researchers from Mount Sinai School of Medicine have found that students enrolled in the Humanities and Medicine (HuMed) program are as successful in medical school as students who fulfill the traditional pre-med requirements. HuMed students are accepted in their sophomore year of college and complete their studies in the humanities or social sciences before matriculating at Mount Sinai School of Medicine. They are not required to take the traditional pre-med science courses and do not have to take the MCAT. These results indicate that a liberal arts undergraduate preparation for medical school is as beneficial as the traditional science preparation. The research is published in the August issue of Academic Medicine.

31 Jul 2010

Research establishes bases of possible future pharmaceutical drugs to combat AIDS virus

The doors are closing on the AIDS virus. The scientific community continues to strive to find the formula that will halt the advance of one of the viruses that has sparked most scientific interest over recent years. A study by the Consejo Superior de Investigaciones Cient-ficas (CSIC) and led by Mr F-lix Go-i, director of the Biophysics Unit at the CSIC-University of the Basque Country Mixed Centre, has developed a method of attack against the AIDS virus The method involves creating a prevention system, i.e. an 'armour' in the cells that are likely to be infected and thus impede, de facto, the virus from accessing them and starting to act on their immunological system.

31 Jul 2010

Johns Hopkins scientist wins $2.5M NIH Director's Pioneer Award

A Johns Hopkins scientist who proposes to design and create an all-new series of novel drugs is one of 17 winners of a special grant known as a Director's Pioneer Award from the National Institutes of Health.

27 Jul 2010

New chemical method for drug design, agrichemicals

University of Delaware scientist Donald Watson is part of a research team that has discovered an easier method for incorporating fluorine into organic molecules, giving chemists an important new tool in developing materials ranging from new medicines to agricultural chemicals.

30 Jun 2010

TRL commences operations at San Diego facility with focus on biological drugs for autoimmune diseases

Tanabe Research Labs USA, Inc. (TRL) today announced commencement of its new operations at the TRL facility in San Diego with a focus on biological drugs for the treatment of autoimmune diseases. TRL began its new activities in May with the appointment of three new senior executives: Masaki Yamada, Ph.D., Chief Executive Officer; Toshihiro Hosaka, Ph.D., Senior Vice President, and Roland Newman, Ph.D., VP and Chief Scientific Officer.

28 Jun 2010