Organic chemistry News and Research

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New bio-active natural products with huge potential as drugs

Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives.

8 Sep 2020

UV researchers patent a kit to detect GHB in alcoholic beverages and soft drinks

The MODeLiC (Organic Materials for Controlled Detection and Release) research team led by Ana María Costero, Professor of Organic Chemistry at the University of Valencia (UV), has developed a system with colorimetric sensors that change color when there is γ-hydroxybutyric acid (GHB) in a beverage.

8 Sep 2020

FlowSyn system enables rapid evaluation of critical reactions

Uniqsis reports how a FlowSyn™ continuous flow reactor installed at Adesis Inc. of New Castle, DE (USA) is assisting them in evaluating custom synthetic routes for compounds along with improving existing batch manufacturing processes.

From Uniqsis Ltd 3 Sep 2020

Improved type of PROTAC enhances intracellular accumulation and protein knockdown

Cancer therapies sometimes involve drugs that mediate the breakdown of specific intracellular proteins that participate in cancer formation and proliferation.

27 Aug 2020

New book series advances the development of pharmaceutical agents for treating neurological, CNS disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

21 Aug 2020

Scientists design new catalyst to widen the range of target chemical substances for radical reactions

Organocatalysts consisting of organic compounds without metal elements are receiving much attention as next generation catalysts in the hope of reducing environmental burden and coping with exhaustion/rising prices of rare metals.

12 Aug 2020

Existing drug used to treat alcoholism is potentially effective against COVID-19

A team of chemists from HSE University and the Zelinsky Institute of Organic Chemistry used molecular modelling to find out that two medications that have been known for a long time can be used to fight SARS-CoV-2.

5 Aug 2020

Chlamydiae need a lot of glutamine to multiply in human cells

If chlamydiae want to multiply in a human cell, the first thing they need is a lot of glutamine. Würzburg researchers have clarified how the pathogenic bacteria obtain this substance.

3 Aug 2020

Scientists identify cellular mechanism that shows promise in treating cancer

Fighting cancer often means employing a suite of techniques to target the tumor and prevent it from growing and spreading to other parts of the body.

22 Jul 2020

Modern mass spectrometry applications in research

Bentham Science Publishers have recently published a new book series on mass spectrometry applications, in research.

6 Jul 2020

Researchers discover novel class of safer analgesics

Researchers at LSU Health New Orleans Neuroscience Center of Excellence and colleagues have discovered a new class of pipeline drugs to relieve pain and reduce fever without the danger of addiction or damage to the liver or kidneys.

6 Jul 2020

Synthesis of bioactive natural compounds for the battle against cancer

Phytoalexins are bioactive phytochemicals that have attracted much attention in recent years due to their health-promoting effects in humans and their vital role in plant health.

25 Jun 2020

NIST updates its database of chemical fingerprints

The National Institute of Standards and Technology has updated its database of chemical fingerprints, called mass spectra, that are used to identify unknown chemical compounds.

17 Jun 2020

Rice lab's fluorescent tag project reveals new method to kill tumors

A Rice University lab's project to make better fluorescent tags has turned into a method to kill tumors. Switching one atom in the tag does the trick.

11 Jun 2020

Novel fungal compound can turn on p53 gene in cancer cells

Cancers cells use a special technique to propagate; they delete their "programmed death" gene through mutation, "forget" to die when their lifetime is over, and continue to grow instead.

11 Jun 2020

Focusing on clinical drug research for dementia

Frontiers in Clinical Drug Research - Dementia is a book series which presents comprehensive reviews about research on Dementia, a term which references the loss of brain function associated with Alzheimer's disease and other related medical conditions.

5 Jun 2020

New book series brings updated reviews on diabetes and obesity

Frontiers in Clinical Drug Research - Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases - diabetes and obesity.

27 May 2020

Updates on stem cell therapeutics and regenerative medicine

Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come.

27 May 2020

Hydrocarbon bonds may help synthesize large range of novel organic molecules

The most common chemical bond in the living world -- that between carbon and hydrogen -- has long resisted attempts by chemists to crack it open, thwarting efforts to add new bells and whistles to old carbon-based molecules.

22 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020