Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

“Laboratory testicles” could solve male infertility mysteries

The testis is responsible for sperm production and testosterone synthesis. Abnormalities in testis development and function lead to disorders of sex development (DSD) and male infertility. Currently, no in vitro system exists for modeling the testis.

20 Feb 2024

New breakthrough in pancreatic cancer research could help slow the disease's deadly spread

Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of California, Davis have reached a new breakthrough in pancreatic cancer research-;eight years in the making. It could help slow the disease's deadly spread.

14 Feb 2024

New drug targets key mechanism in ALS, protects motor neurons

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS).

8 Feb 2024

Study advances search for a blood test to identify disease-associated changes in the brain

Researchers in a Johns Hopkins Children's Center-led study that used genetic material from human blood and lab-grown brain cells say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.

8 Feb 2024

Study pinpoints a protein linked to metastatic pancreatic cancer

Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed.

7 Feb 2024

Tecan offers end-to-end solutions for cellomics: automated workflows from single-cell dispensing to 3D spheroid analysis

Tecan is proud to offer end-to-end cellomics workflow solutions, including cell seeding and culture with quality control and monitoring, through drug dosing to live-cell imaging and analysis. This comprehensive offering enables laboratories to improve the reliability, reproducibility and throughput of their workflows, addressing key challenges in the growing field of 3D cell biology.

5 Feb 2024

Engrailed-1 protein promotes pancreatic cancer progression and metastasis

Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed.

2 Feb 2024

mRNA therapy revives p53 to combat ovarian tumors

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study by Goethe University Frankfurt and University Hospital Frankfurt offers hope that this could change in the medium term.

24 Jan 2024

Lab-grown mini-placentas shed light on pre-eclampsia and pregnancy disorders

Scientists have grown 'mini-placentas' in the lab and used them to shed light on how the placenta develops and interacts with the inner lining of the womb – findings that could help scientists better understand and, in future, potentially treat pre-eclampsia.

17 Jan 2024

Long-term expansion and self-organization of human fetal brain organoids

Researchers establish fetal brain organoids as a versatile platform for brain cancer modeling.

12 Jan 2024

First organoid model of the human conjunctiva produced

The Organoid group at the Hubrecht Institute produced the first organoid model of the human conjunctiva. These

11 Jan 2024

€1.6M project aims to crack the code of degradation-resistant tumors

An international research project on the subject of "Understanding and targeting degradation-resistant tumors" has been granted funding of 1.655 million euros through the German-Israeli Project Cooperation (DIP) program.

11 Jan 2024

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

In our latest interview, News-Medical speaks with Rosanna Zhang from ACROBiosystems about utilizing organoids for disease modeling in the field of neuroscience research.

From Aneuro - An ACROBiosystems Brand 11 Jan 2024

3D mini-organs from human fetal brain tissue unlock new frontier in brain research

Scientists have developed 3D mini-organs from human fetal brain tissue that self-organize in vitro. These lab-grown organoids open up a brand-new way of studying how the brain develops.

8 Jan 2024

Revolutionary study reveals Lactobacillus acidophilus could ward off liver cancer linked to fatty liver disease

Probiotic supplementation with Lactobacillus acidophilus could help prevent non-alcoholic fatty liver disease.

8 Jan 2024

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

4 Jan 2024

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for Pediatric Oncology in the Netherlands mapped this childhood tumor at the level of individual cancer and immune cells.

4 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

New drug screening system helps uncover promising target for pancreatic cancer treatments

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine.

26 Dec 2023

Organoids News and Research

Further Reading

“Laboratory testicles” could solve male infertility mysteries

New breakthrough in pancreatic cancer research could help slow the disease's deadly spread

New drug targets key mechanism in ALS, protects motor neurons

Study advances search for a blood test to identify disease-associated changes in the brain

Study pinpoints a protein linked to metastatic pancreatic cancer

Tecan offers end-to-end solutions for cellomics: automated workflows from single-cell dispensing to 3D spheroid analysis

Engrailed-1 protein promotes pancreatic cancer progression and metastasis

mRNA therapy revives p53 to combat ovarian tumors

Lab-grown mini-placentas shed light on pre-eclampsia and pregnancy disorders

Long-term expansion and self-organization of human fetal brain organoids

First organoid model of the human conjunctiva produced

€1.6M project aims to crack the code of degradation-resistant tumors

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

3D mini-organs from human fetal brain tissue unlock new frontier in brain research

Revolutionary study reveals Lactobacillus acidophilus could ward off liver cancer linked to fatty liver disease

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

Imbalances in folic acid and vitamin B12 can alter brain development in mice

How immune cells shape our earliest breaths

New drug screening system helps uncover promising target for pancreatic cancer treatments

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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