Orthopedics News and Research

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Noncoding DNA sequence required for epidermal differentiation

The differentiation of human epidermis is controlled and stabilized by a long noncoding RNA termed terminal differentiation-induced noncoding RNA acting through a post-transcriptional mechanism, the results of an innovative US study indicate.

7 Dec 2012

Gene therapy could represent new treatment option for severe orthopaedic injuries

Gene therapy involving modified stem cells obtained from fatty tissue and bone marrow could represent a new option for the treatment of severe orthopaedic injuries to the extremities.

7 Dec 2012

Mutations signaling poor neuroblastoma prognosis identified

Children with neuroblastoma who have mutations in the ARID1A and ARID1B genes in their tumors have a poor prognosis compared with those without these alterations, show study findings.

4 Dec 2012

Swedish Medical Center/First Hill named among Leapfrog Group's 2012 Top Hospitals

The Leapfrog Group's annual class of 'Top Hospitals' – just 89 from a field of nearly 1,200 – will be announced today in Baltimore, Md., and includes Swedish Medical Center/First Hill for the third year in a row. The announcement will take place at Leapfrog's Annual Meeting.

4 Dec 2012

Vitamin D receptor polymorphism may protect against osteoporosis

A polymorphism in the vitamin D receptor gene significantly influences risk for osteoporosis, suggest results from a meta-analysis of 26 studies.

3 Dec 2012

Report finds low infection rate for hip replacement or revision procedures at HSS

For the fourth year in a row, Hospital for Special Surgery has an infection rate that is significantly lower than the New York State average for hip replacement or revision surgeries, according to the 2011 report on hospital infection rates just released by the State Department of Health.

1 Dec 2012

Fn14 gene plays a role in growth and spread of non-small cell lung cancer tumors

Lung cancer researchers at St. Joseph's Hospital and Medical Center in Phoenix, Ariz., in collaboration with researchers at the Translational Genomics Research Institute and other institutions, have identified a gene that plays a role in the growth and spread of non-small cell lung cancer tumors, opening the door for potential new treatment options.

30 Nov 2012

GPs fitting more into patient consultations

GPs are fitting much more into patient consultations than they were a decade ago but the average length of the consultation has stayed the same, research led by the University of Sydney shows.

27 Nov 2012

Nonfunctional MED12 gene linked to chemotherapy resistance

Research published in Cell shows that people with tumors that have a nonfunctional version of the mediator 12 gene are resistant to drugs used to treat lung and colon cancer such as gefitinib.

26 Nov 2012

Colorectal cancer patient siblings ‘deserve screening’

Colorectal cancer screening should be offered to the siblings of affected patients, recommends a team of researchers from Hong Kong.

22 Nov 2012

Rituximab may help patients with aPL-related clinical problems

Rituximab, a drug used to treat cancer and arthritis, may help patients with antiphospholipid antibodies (aPLs) who suffer from aPL-related clinical problems that do not respond to anticoagulation, such as cardiac disease and kidney disease, according to a new study by rheumatology researchers at Hospital for Special Surgery. The study appears online ahead of print, in the journal Arthritis and Rheumatism.

21 Nov 2012

Glycoprotein gene flags up heart disease

The glycosylphosphotidylinositol-anchored membrane glycoprotein CD14 gene significantly predicts cardiovascular mortality in adults aged 65 years or over, research shows.

20 Nov 2012

New genetic insight into Alzheimer’s disease

A rare mutation in the gene encoding the triggering receptor expressed on myeloid cells 2 has a potent effect on the risk for late-onset Alzheimer’s disease, two studies published in The New England Journal of Medicine suggest.

20 Nov 2012

3DISC to debut FireCR+M Readers at RSNA annual meeting

3DISC, a manufacturer of digital imaging solutions, will debut its next-generation FireCR+M Medical and FireCR+M Veterinary Readers at the 2012 Radiological Society of North America (RSNA) meeting in Chicago Nov. 25-30 (Booth #4406).

20 Nov 2012

AGTR2 gene variant predicts risk for preeclampsia

Carriers of a variant of the angiotensin II receptor, type 2 gene have increased risk for preeclampsia during pregnancy if they are also overweight or obese, show study results published in Placenta.

19 Nov 2012

HHS, SJHH launch integrated Radiology and Nuclear Medicine peer review pilot project

The integrated department of diagnostic services at Hamilton Health Sciences and St. Joseph's Healthcare Hamilton announced today that it is launching a city-wide, integrated Radiology and Nuclear Medicine peer review pilot project.

17 Nov 2012

First HSS medical symposium to take place in Rio de Janeiro from Nov. 28-29

The first medical symposium in Brazil presented by Hospitalys Ortopedia in Rio de Janeiro and New York City's Hospital for Special Surgery (HSS) will take place November 28 and 29 in Rio de Janeiro.

16 Nov 2012

Colon cancer risk: Supplements no substitute for dietary fiber

Dietary supplementation with resistant starch does not reduce long-term colorectal cancer risk in patients with Lynch syndrome, shows the CAPP2 study.

15 Nov 2012

Taste receptor governs respiratory infection susceptibility

The bitter taste receptor TAS2R38 may play a role in innate defense, say researchers, who have found that variations in the TAS2R38 gene may regulate susceptibility to respiratory infection.

12 Nov 2012

Whole genome sequencing could become prenatal standard of care

Whole genome sequencing of the DNA code of prenatal samples accurately and quickly identifies the location of chromosomal abnormalities, and could become a prenatal standard of care, researchers propose.

9 Nov 2012