Osteoblast News and Research

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Heat and gut microbiota promote stronger bones

Osteoporosis, a bone disease linked to ageing, is characterized by a loss of bone density, micro-architectural deterioration of the bones and an increased risk of fractures.

11 Sep 2020

A tiny fish could end painful metabolic and genetic bone diseases

In a study published recently in Communications Biology, researchers led by Kanazawa University explain how a tiny fish could help end painful metabolic and genetic bone diseases.

15 Jul 2020

Specific gut microbes have the capacity to affect normal skeletal growth and maturation

Microbes are often seen as pathogens that cause disease, but the picture is actually more complex than that limited view.

28 Jan 2020

Melatonin promises to help reduce bone loss in space flight

New research suggests that the problem of bone loss caused by microgravity conditions in space flight may be successfully treated using the time-tested drug melatonin. Melatonin increases the level of calcitonin in bone, which suppresses the bone-destroying activity of osteoclastic cells and helps maintain bone density.

4 Sep 2019

Study maps bone marrow niche populations and their differentiation paths

Bone marrow contains biological factories, which pump out billions of new blood cells daily. The non-blood cells that maintain this production also have the potential to produce bone, fat and cartilage.

1 Aug 2019

Jefferson researcher discovers a population of bone cells that subdues cancer

In breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary disease and thought they were cancer-free.

13 May 2019

Researchers identify novel regulatory factor in bone formation

Researchers report the identification of a novel transcription factor that helps regulate the differentiation of mesenchymal stem cells into bone in mice.

11 Mar 2019

Researchers show how mechanical stress affects bone development

Researchers at Okayama University show how mechanical stress at very early stages of bone development alters expression pattern of the non-collagenous matrix responsible for biological property of the bone.

22 Jan 2019

Study determines impact of antibiotic perturbation of the gut microbiome on skeletal health

Microbes are often seen as pathogens that cause disease and antibiotics have been used successfully to combat these foreign invaders. In reality, the picture is more complex.

17 Jan 2019

Research uncovers new mechanism involved in bone formation

Osteoporosis is a disease that causes bones to fracture easily due to a reduction in both bone mass and quality. Aging is one of its leading causes, and it is estimated that around 200 million people are affected worldwide.

5 Sep 2018

PolyU researchers design new self-fitting scaffold to induce bone regeneration

Researchers from The Hong Kong Polytechnic University have designed and fabricated a high performing self-fitting bone scaffold by combining a shape memory foam and hydroxyapatite (the principal mineral component of bone tissue).

17 Aug 2018

Vallum receives FDA clearance to market PEEK spinal interbody fusion device

Vallum Corporation, a medical device company, today announced that it has received clearance from the U.S. Food and Drug Administration to market a polyetheretherketone spinal interbody fusion device with a PEEKplus nanotextured surface created by Vallum's proprietary and patented Accelerated Neutral Atom Beam technology.

17 Jul 2018

Origami inspires researchers to develop new solution for tissue regeneration

Origami - the Japanese art of folding paper into shapes and figures - dates back to the sixth century. At UMass Lowell, it is inspiring researchers as they develop a 21st-century solution to the shortage of tissue and organ donors.

25 May 2018

New study launched to examine effects of rheumatologic agent on bone health

Researchers at Hospital for Special Surgery have launched a pilot study to see how a drug that treats several related autoimmune disorders affects the skeleton.

7 May 2018

Biotechnology startup receives FDA clearance for synthetic bone graft substitute

A biotechnology startup enabled by UC Davis, Molecular Matrix Inc., has received Food and Drug Administration clearance for a carbohydrate-based polymer that can help injured bones heal and regrow.

27 Jan 2018

Research reveals role of nanophenomenon in stimulating bone-repair process

Researchers at the Institut Català de Nanociència i Nanotecnologia have resolved one of the great unknowns in bone self-repair: how the cells responsible for forming new bone tissue are called into action.

19 Jan 2018

Silky webs of spiders may hold secrets to repairing our skeletons

Some secrets to repairing our skeletons might be found in the silky webs of spiders, according to recent experiments guided by supercomputers. Scientists involved say their results will help understand the details of osteoregeneration, or how bones repair themselves.

20 Dec 2017

Research suggests general mechanism by which dietary fats affect cellular physiology

You are what you eat when it comes to fat, report scientists from McGovern Medical School at The University of Texas Health Science Center at Houston in the journal Science Advances.

1 Dec 2017

New study elucidates osteoblast production during bone regeneration

How osteoblasts are supplied during bone regeneration has been controversial among bone researchers. According to Atsushi Kawakami, an Associate Professor who specializes in tissue regeneration and led the study, scientists disagree on how these cells are made.

3 Nov 2017

Research sheds light on how bones affect appetite and metabolism

Your skeleton is much more than the structure supporting your muscles and other tissues. It produces hormones, too. And Mathieu Ferron knows a lot about it.

1 Nov 2017