Osteosarcoma News and Research

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Between two and three percent of all childhood cancers are osteosarcoma. Because osteosarcoma usually develops from osteoblasts, it most commonly affects children and young adults experiencing their adolescent growth spurt. Boys and girls have a similar incidence rate until later in their adolescence, when boys are more commonly affected. While most tumors occur in larger bones, such as the femur, tibia, and humerus, and in the area of the bone that has the fastest growth rate, they can occur in any bone. The most common symptom is pain, but swelling and limited movement can occur as the tumor grows.

Osteosarcoma is an orphan disease with approximately 1,200 new cases diagnosed in the United States each year. A similar incidence of the disease exists in Europe. According to the Children's Oncology Group (COG), the survival of children with osteosarcoma has remained at 60-65 percent since the mid-1980s. The standard treatment for osteosarcoma is tumor resection with combination chemotherapy before and after surgery.
VA begins distributing disability benefits to Vietnam Veterans exposed to Agent Orange

VA begins distributing disability benefits to Vietnam Veterans exposed to Agent Orange

Spectrum submits complete response to FDA's CRL for FUSILEV to treat colorectal cancer

Spectrum submits complete response to FDA's CRL for FUSILEV to treat colorectal cancer

Sandoz initiates voluntary recall of Methotrexate Injection

Sandoz initiates voluntary recall of Methotrexate Injection

Researchers identify signaling pathway that promotes metastasis of pediatric bone cancer

Researchers identify signaling pathway that promotes metastasis of pediatric bone cancer

14 global studies on osteoporosis medications FORTEO and EVISTA to be presented at ASBMR 2010

14 global studies on osteoporosis medications FORTEO and EVISTA to be presented at ASBMR 2010

Researchers investigate 'friendly bacteria' to kill bone cancer cells

Researchers investigate 'friendly bacteria' to kill bone cancer cells

Advanced Targeting Systems receives NCI award to advance SP-SAP drug

Advanced Targeting Systems receives NCI award to advance SP-SAP drug

Advaxis receives USPTO patent for Listeria vaccine

Advaxis receives USPTO patent for Listeria vaccine

Complete Genomics, SAIC-Frederick collaborate to validate somatic mutations from pediatric cancer cases

Complete Genomics, SAIC-Frederick collaborate to validate somatic mutations from pediatric cancer cases

Cancer Research Technology grants Scancell licence to use 105AD7 human antibody

Cancer Research Technology grants Scancell licence to use 105AD7 human antibody

BCF publishes two new patient publications

BCF publishes two new patient publications

Michigan State University researchers analyze histiocytic sarcomas

Michigan State University researchers analyze histiocytic sarcomas

Takeda enters co-promotion agreement with Janssen Pharma for VELCADE

Takeda enters co-promotion agreement with Janssen Pharma for VELCADE

MEDIHONEY dressings effective in treating chronic wounds in children

MEDIHONEY dressings effective in treating chronic wounds in children

Nine-year-old cancer patient benefits from procedure to magnetically extend her leg

Nine-year-old cancer patient benefits from procedure to magnetically extend her leg

Spectrum Pharmaceuticals reports $15.7M revenue from ZEVALIN sales in 2009

Spectrum Pharmaceuticals reports $15.7M revenue from ZEVALIN sales in 2009

Agent Orange exposure: VA adds three new illnesses to list of health problems

Agent Orange exposure: VA adds three new illnesses to list of health problems

Simcere Pharmaceutical completes Phase IV clinical study of Endostar

Simcere Pharmaceutical completes Phase IV clinical study of Endostar

PCI Biotech completes treatment of third dose group in phase I/II study of Amphinex in cancer patients

PCI Biotech completes treatment of third dose group in phase I/II study of Amphinex in cancer patients

Bone implants that support and release chemotherapeutical agents in ciclodextrin nanocapsule

Bone implants that support and release chemotherapeutical agents in ciclodextrin nanocapsule