Overactive Bladder News and Research

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Overactive bladder (OAB) is a urological condition defined by a set of symptoms: "urgency, with or without urge incontinence, usually with frequency and nocturia."

Urologists report success in treating bladder issues, pelvic pain through neuromodulation technique

Millions of people suffer from bladder dysfunction, including about 30 million in the U.S. One in seven women experience chronic pelvic pain. These are not only health issues, but quality of life issues.

18 Aug 2015

Botulinum toxin A effective for treating bladder disorders

While Botulinum toxin A (BTX-A), known to the public as Botox, is commonly associated with smoothing wrinkles for a more youthful appearance, three studies presented at the 110th Annual Scientific Meeting of the American Urological Association are proving BTX-A to be more than just a cosmetic solution.

17 May 2015

FDA grants tentative approval to Amerigen's ANDA for generic version of Toviaz

Amerigen Pharmaceuticals Limited today announced that the U.S. Food and Drug Administration has granted tentative approval to the Company's Abbreviated New Drug Application (ANDA) for a generic version of Toviaz (Fesoterodine Fumarate Extended-release Tablets, 4mg and 8mg).

30 Apr 2015

Existing drug could help treat MS, other neurological diseases

Damage to myelin, the fatty insulator that enables communication between nerve cells, characterizes multiple sclerosis (MS) and other devastating neurological diseases.

3 Mar 2015

Signostics gets FDA 510k clearance for handheld bladder scanner

Medical device company, Signostics, announced today it has clearance from the U.S. Food and Drug Administration to launch the SignosRT Bladder, the company’s new hand-held bladder scanner.

15 Jan 2015

Sleep-wake cycles are genetically connected to the bladder

If you think sleep problems and bladder problems are a fact of life in old age, you may be right. A new report appearing in the November 2014 issue of The FASEB Journal, shows that our sleep-wake cycles are genetically connected to our bladder, and disruptions to one may cause problems with the other.

31 Oct 2014

Storage symptoms more severe in men with comorbid diabetes

A study of men with lower urinary tract symptoms and benign prostatic hyperplasia suggests that the presence of comorbid diabetes is associated with more severe urological symptoms.

22 Sep 2014

OABSS reveals impact of symptoms on women’s quality of life

The Overactive Bladder Symptom Score questionnaire is valuable for assessing the impact of OAB symptoms on women’s health-related quality of life, shows a large survey of Japanese women.

22 Sep 2014

Urinary nerve growth factor shows diagnostic value

Urinary nerve growth factor could be a useful biomarker for the diagnosis of overactive bladder and a predictive biomarker to help guide treatment, Chinese researchers believe.

17 Sep 2014

Sacral neuromodulation augments efficacy of antimuscarinics in OAB

The addition of sacral neuromodulation to antimuscarinic pharmacotherapy offers significant benefits over antimuscarinics alone in the treatment of women with idiopathic overactive bladder, study findings show.

17 Sep 2014

Loyola announces opening of new acupuncture clinic for patients with pelvic health disorders

Loyola University Health System will open an acupuncture clinic for men and women with pelvic health disorders this fall. The clinic will use acupuncture to treat patients with common conditions such as pelvic pain, nausea from pelvic surgery, interstitial cystitis, painful bladder syndrome, postoperative pain, prostatitis and overactive bladder.

11 Sep 2014

Transplantation of B10 cells helps inhibit development of bladder fibrosis post SCI

A team of researchers from Korea and Canada have found that transplantation of B10 cells (a stable immortalized human bone marrow derived -mesenchymal stem cell line; B10 hMSC) directly into the bladder wall of mice modeled with spinal cord injury (SCI) helped inhibit the development of bladder fibrosis and improved bladder function by promoting the growth of smooth muscle cells in the bladder.

4 Sep 2014

No added benefit determined from Mirabegron for mortality, morbidity and quality of life

Mirabegron (trade name: Betmiga) has been approved since December 2012 for the treatment of adults with overactive bladder.

3 Sep 2014

Transobturator tape improves OAB symptoms including nocturia

The use of transobturator tape offers significant relief from symptoms of overactive bladder in patients with mixed urinary incontinence, study findings indicate.

1 Sep 2014

Gene variants linked to overactive bladder and prolapse in women

A systematic review and meta-analysis of genetic association studies reveals a number of genetic variations associated with overactive bladder and pelvic organ prolapse in women.

28 Aug 2014

NGS issues positive coverage decision for PTNS to manage symptoms of OAB

Uroplasty, Inc., a medical device company that develops, manufactures and markets innovative proprietary products for the treatment of voiding dysfunctions, today announced that National Government Services has issued a positive coverage decision for Posterior Tibial Nerve Stimulation (PTNS) for the treatment of urinary urgency, urinary frequency and urge incontinence associated with overactive bladder (OAB). Coverage for the proprietary Urgent PC device was effective August 10, 2014.

12 Aug 2014

$Sacral magnetic stimulation effective in refractory stress incontinence$