Oxidative Stress News and Research

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Oxidative Stress is a condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.

Molecular effects of insufficient sleep uncovered

Results from a sleep laboratory study show striking changes in gene expression associated with sleep deprivation.

27 Feb 2013

Two renowned SCCP scientists earn national recognition from Society of Toxicology

Two renowned scientists at the South Carolina College of Pharmacy (SCCP) have garnered national recognition from the Society of Toxicology (SoT), which named them recipients of two of its individual annual awards. It is the first time these awards have gone to individuals from the same College.

27 Feb 2013

Antioxidant boosts liver transplant outcomes

Infusion of N-acetylcysteine in liver donors can significantly improve the outcome of transplantation, research shows.

25 Feb 2013

CB2 receptors might serve as potential therapeutic targets for cerebral ischemia

A new study published in the March issue of The American Journal of Pathology suggests that cortical type 2 cannabinoid (CB2) receptors might serve as potential therapeutic targets for cerebral ischemia.

22 Feb 2013

Researchers use familial and sporadic patient-derived iPSCs to model Alzheimer's disease

Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell Stem Cell has successfully modeled Alzheimer's disease (AD) using both familial and sporadic patient-derived induced pluripotent stem cells (iPSCs), and revealed stress phenotypes and differential drug responsiveness associated with intracellular amyloid beta oligomers in AD neurons and astrocytes.

21 Feb 2013

Oxidative stress: the price of sucrose pain relief in neonates

Although sucrose significantly reduces the pain experienced by preterm neonates undergoing heel lance, it is associated with significant increases in adenosine triphosphate use and oxidative stress, the results of a US study indicate.

19 Feb 2013

Oxidized CaMKII may increase risk of death in diabetics following heart attack

Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart enzyme, which leads to death of pacemaker cells in the heart, abnormal heart rhythm, and increased risk of sudden death in diabetic mice following a heart attack.

18 Feb 2013

Researchers identify new molecular pathway involved in alveoli growth

In a study of mice, researchers at Johns Hopkins have identified a new molecular pathway involved in the growth of tiny air sacs called alveoli that are crucial for breathing. The scientists say their experiments may lead to the first successful treatments to regrow the air sacs in people who suffer from diseases such as emphysema in which the air sacs have been destroyed by years of smoking.

15 Feb 2013

Interleukin 6 variant associated with developmental problems after preterm birth in females

In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in San Francisco, researchers will report that variation in a gene involved in inflammation is associated with developmental problems after preterm birth in females, but not males.

13 Feb 2013

Inhibiting JNK enzyme protects against ischemic/reperfusion injury

Using two different compounds they developed, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to show in animal models that inhibiting a specific enzyme protects heart cells and surrounding tissue against serious damage from heart attacks.

10 Feb 2013

Physical activity levels may affect men’s semen quality

The quality of young men’s sperm may be influenced by how active their lifestyle is, report researchers.

6 Feb 2013

DHA more effective than EPA in preventing liver inflammation and fibrosis

Research at Oregon State University has found that one particular omega-3 fatty acid has a powerful effect in preventing liver inflammation and fibrosis - common problems that are steadily rising along with the number of Americans who are overweight.

6 Feb 2013

Eating brightly colored fruit and veg may help prevent ALS

Having a high intake of carotenoids, compounds that give certain fruits and vegetables their distinctive coloring, can reduce a person’s risk for developing amyotrophic lateral sclerosis or motor neurone disease, suggest study findings.

4 Feb 2013

Selenium supplements do not reduce risk of developing heart disease according to current evidence

A systematic review published today in The Cochrane Library finds that in well-nourished adults current evidence does not support selenium for preventing heart disease.

31 Jan 2013

Increasing age, male sex and adiposity risk factors for metabolic syndrome in children

Metabolic syndrome is more likely to affect children who are obese than overweight or non-overweight and who have other characteristics associated with the disorder, such as high blood pressure or insulin resistance. A new comprehensive and systematic review of the medical literature on metabolic syndrome in children that probed deeper to evaluate the risk associated with gender, ethnicity, and geography was published in Metabolic Syndrome and Related Disorders, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

31 Jan 2013

SOD1 enzyme protects cells by regulating cell energy and metabolism

Just like a comic book super hero, you could say that the enzyme superoxide dismutase (SOD1) has a secret identity. Since its discovery in 1969, scientists believed SOD1's only role was to protect living cells against damage from free radicals. Now, researchers at the Johns Hopkins Bloomberg School of Public Health have discovered that SOD1 protects cells by regulating cell energy and metabolism. The results of their research were published January 17, 2013, in the journal Cell.

30 Jan 2013

Consuming carotenoid-rich foods may help prevent or delay onset of amyotrophic lateral sclerosis

New research suggests that increased consumption of foods containing colorful carotenoids, particularly beta-carotene and lutein, may prevent or delay the onset of amyotrophic lateral sclerosis (ALS).

29 Jan 2013

Regular deep-fried food consumption may increase risk of prostate cancer

Regular consumption of deep-fried foods such as French fries, fried chicken and doughnuts is associated with an increased risk of prostate cancer, and the effect appears to be slightly stronger with regard to more aggressive forms of the disease, according to a study by investigators at Fred Hutchinson Cancer Research Center.

29 Jan 2013

Yoga has positive effects on major psychiatric disorders

Yoga has positive effects on mild depression and sleep complaints, even in the absence of drug treatments, and improves symptoms associated with schizophrenia and ADHD in patients on medication, according to a systematic review of the exercise on major clinical psychiatric disorders.

25 Jan 2013

Multiple vascular benefits in salt restriction

Restricting salt intake reverses vascular endothelial dysfunction in people with moderately increased blood pressure, shows a randomized study published in the Journal of the American College of Cardiology.

22 Jan 2013