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USPTO awards Peregrine Pharmaceuticals patent for anti-viral uses of phosphatidylserine targeting antibodies

Peregrine Pharmaceuticals, Inc. today announced that the U.S. Patent and Trademark Office has issued U.S. Patent Number 7,611,704, which includes broad claims covering anti-viral uses of phosphatidylserine (PS)-targeting antibodies including Peregrine's lead clinical compound, bavituximab. PS is a unique marker exposed on the surface of virally infected cells that can be targeted to treat a broad spectrum of virus infections.

5 Nov 2009

NIAID awards Pulmatrix $2.2M grant for developing novel influenza therapeutics

Pulmatrix, a clinical stage biotechnology company discovering and developing a new class of therapies for the treatment and prevention of infectious and progressive respiratory diseases, today announced that it has been awarded a grant for $2.2 million from the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), aimed at advancing the development of novel influenza therapeutics for the treatment of seasonal and pandemic influenza.

2 Nov 2009

Scientists report a major step forward in the development of an effective therapy against Nipah virus

A collaborative research team from the Uniformed Services University of the Health Sciences (USU), Australian Animal Health Laboratory and National Cancer Institute, a component of the National Institutes of Health, reports a major step forward in the development of an effective therapy against two deadly viruses, Nipah virus and the related Hendra virus.

31 Oct 2009

Patients who acquire SSTIs in healthcare settings may stay longer in hospitals to control the infection

Patients who acquire skin and soft tissue infections (SSTIs) in a hospital or other healthcare setting may be more likely to receive inappropriate antibiotic therapy at the beginning of their treatment. As a result, they also may have significantly longer hospital stays to control the infection.

31 Oct 2009

Viral protein could be a major player in SARS virulence

Ever since the previously unknown SARS virus emerged from southern China in 2003, University of Texas Medical Branch at Galveston virologists have focused on finding the source of the pathogen's virulence - its ability to cause disease. In the 2003 epidemic, for example, between 5 and 10 percent of those who fell sick from the SARS virus died, adding up to more than 900 fatalities worldwide.

30 Oct 2009

TGen to secure emergency FDA approval for 2009 H1N1 flu test

The Phoenix-based non-profit Translational Genomics Research Institute (TGen) announced today that, along with a business collaborator, it will submit a request to the U.S. Food and Drug Administration for emergency use of a new test to diagnose the 2009 H1N1 swine flu virus.

30 Oct 2009

Study: Short-term use of COX-2 inhibitors may help prevent gastric cancer

Elevated expression of COX-2 is observed in a wide variety of human malignancies, including gastric cancer. Long-term high dose COX-2 inhibitors can inhibit gastric carcinogenesis in animal models, but the possible life-threatening cardiovascular adverse events limit its popular application. Therefore, it is important to evaluate the optimal intervention point of COX-2 inhibitors for inhibiting H. pylori-associated gastric carcinogenesis.

29 Oct 2009

$12.2 million grant from NIH for research on the sexually transmitted bacteria chlamydia

Perhaps the most comprehensive, multi-institutional study yet of the sexually transmitted bacteria chlamydia is under way at the University of Maryland, Baltimore (UMB).

29 Oct 2009

Micronics inks license agreement with Biosearch Technologies

Micronics, Inc., a leading developer of point-of-care molecular diagnostic products, announced today that it has entered into a license agreement with Biosearch Technologies, Inc. (Biosearch) for the right to make, have made, use and sell Micronics’ products that incorporate Biosearch’s proprietary fluorophores and quencher dyes for nucleic acid assays. Under the terms of the worldwide license, Biosearch has granted Micronics a royalty-free use of certain of its chemistries for inclusion in Micronics’ infectious disease tests for sale in underdeveloped countries.

28 Oct 2009

NCMLS organises immunology congress at Nijmegen

How do cells in our immune system recognise dangerous invaders and hazardous cells, such as cancer cells? Answers to this and similar questions are evolving rapidly. A large contributor worldwide to the field of immunology is the NCMLS, Nijmegen Centre for Molecular Life Sciences of the Radboud University Nijmegen Medical Centre. The NCMLS is organising an important scientific congress on this very topic, for which the absolute world top immunology experts are coming to Nijmegen.

27 Oct 2009

Pritzker Olsen to represent 3-year-old child sickened with an E. coli O157:H7 infection

Pritzker Olsen law firm has been retained to represent a 3-year-old child sickened with an E. coli O157:H7 infection and hemolytic uremic syndrome. The child is believed to have contracted the illness at a local apple orchard/ petting zoo in the Twin Cities (MN) area. Preliminary testing indicates that the genetic fingerprint of the E .coli O157:H7 obtained from the child’s stool sample matches the genetic fingerprint of E. coli from llama feces tested at the petting zoo.

26 Oct 2009

Scientists discover new way to help save lives threatened by traumatic injuries

A discovery by scientists at the Oklahoma Medical Research Foundation could help save lives threatened by traumatic injuries like those sustained in car crashes or on the battlefield. The work also holds potential for treating severe infectious diseases and diabetes.

26 Oct 2009

UC Davis' international effort to prevent new pandemics

In hopes of preventing the next global pandemic and a possible death toll into the millions, UC Davis today launches an unprecedented international effort to find and control diseases that move between wildlife and people.

24 Oct 2009

Findings may lead to new vaccine strategies for pulmonary tularemia

Immunologists at the University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh of UPMC and the have found a unique quirk in the way the immune system fends off bacteria called Francisella tularensis, which could lead to vaccines that are better able to prevent tularemia infection of the lungs. Their findings were published today in the early, online version of Immunity.

23 Oct 2009

ZyGEM and Phthisis Diagnostics to develop products for detecting infectious pathogens

ZyGEM Corp. Ltd. and Phthisis Diagnostics today announced that they have entered into an agreement to develop products enabling the detection of infectious pathogens in complex samples, such as stool, blood and water.

23 Oct 2009

Scientists find cause for lupuslike disease in mice

Macrophages, the scavenger cells of the body's immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease.

19 Oct 2009

Sigma-Aldrich launches SAGEspeed, a program for developing human disease models in rodents

Sigma-Aldrich® (Nasdaq: SIAL) today announced the launch of SAGEspeed(TM), a program to develop human disease models in rodents using its proprietary novel CompoZr(TM) Zinc Finger Nuclease (ZFN) gene editing technology (http://www.compozrzfn.com).

19 Oct 2009

First high-throughput analysis of Salmonella Typhi gene

For the first time, researchers are able to look at the need for every gene in a bacterial cell in a single experiment. The new method will transform the study of gene activity and the search for weaknesses in bacterial armouries.

19 Oct 2009

Discovery may yield better understanding of protective gut-dwelling bacteria

Medical researchers have long suspected that obscure bacteria living within the intestinal tract may help keep the human immune system in balance. An international collaboration co-led by scientists at NYU Langone Medical Center has now identified a bizarre-looking microbial species that can single-handedly spur the production of specialized immune cells in mice.

19 Oct 2009

Research study on cowpox virus

In the annals of medicine, Edward Jenner's 1796 vaccination of a young boy against smallpox, using fluid from cowpox blisters, remains a landmark case. In a new study, Kathryn Sykes, a researcher at Arizona State University's Biodesign Institute and her colleagues have taken a fresh look at cowpox.

19 Oct 2009

Pathogen News and Research

USPTO awards Peregrine Pharmaceuticals patent for anti-viral uses of phosphatidylserine targeting antibodies

NIAID awards Pulmatrix $2.2M grant for developing novel influenza therapeutics

Scientists report a major step forward in the development of an effective therapy against Nipah virus

Patients who acquire SSTIs in healthcare settings may stay longer in hospitals to control the infection

Viral protein could be a major player in SARS virulence

TGen to secure emergency FDA approval for 2009 H1N1 flu test

Study: Short-term use of COX-2 inhibitors may help prevent gastric cancer

$12.2 million grant from NIH for research on the sexually transmitted bacteria chlamydia

Micronics inks license agreement with Biosearch Technologies

NCMLS organises immunology congress at Nijmegen

Pritzker Olsen to represent 3-year-old child sickened with an E. coli O157:H7 infection

Scientists discover new way to help save lives threatened by traumatic injuries

UC Davis' international effort to prevent new pandemics

Findings may lead to new vaccine strategies for pulmonary tularemia

ZyGEM and Phthisis Diagnostics to develop products for detecting infectious pathogens

Scientists find cause for lupuslike disease in mice

Sigma-Aldrich launches SAGEspeed, a program for developing human disease models in rodents

First high-throughput analysis of Salmonella Typhi gene

Discovery may yield better understanding of protective gut-dwelling bacteria

Research study on cowpox virus

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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