Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Scripps professor receives pair of notable grants to study kinesin

Sathyanaryanan Puthanveettil, an assistant professor on the Florida campus of The Scripps Research Institute, has been awarded a pair of notable grants to study a critical component of long-term memory formation.

6 Jan 2012

Working Group recommends use of biomarkers in AD clinical trials

A group of thought leaders in Alzheimer's disease says the science is solid and the time has come for more widespread use of biomarkers in Alzheimer disease (AD) clinical trials, to speed the identification of effective disease-modifying treatments for this incurable disorder.

5 Jan 2012

NGP receives investment from Abbott to develop NGP 555 for AD

NeuroGenetic Pharmaceuticals, Inc. (NGP), a privately held biopharmaceutical company focused on Alzheimer's disease (AD) therapeutics, has received an investment from Abbott Biotech Ventures.

5 Jan 2012

Researchers identify candidate genes for histiocytoid cardiomyopathy

Researchers are closing in on a rare genetic disorder causing a heart condition in infants. Histiocytoid cardiomyopathy (HC) often causes sudden death before a child reaches 2 years of age. Gene analysis is helping to narrow the many theories surrounding the genetic basis of HC.

4 Jan 2012

CHEST Foundation awards $100,000 for development of blood test for lung cancer

Lung cancer takes a heavy toll, contributing to more cancer deaths in the United States each year than breast, prostate and colon cancers combined. Contributing to this poor prognosis is the fact that lung cancer often goes undetected until the disease has reached an advanced and more difficult-to-treat stage.

31 Dec 2011

Journal highlights safe use of point-of-care testing technologies

Many medical tests that once required sending samples to a laboratory and waiting for results can now be rapidly performed at the patient's bedside. As these point-of-care testing (POCT) technologies are increasingly integrated into patient care, careful attention is needed to protect patient safety and avoid medical errors, according to this month's special issue of Point of Care: The Journal of Near-Patient Testing & Technology.

28 Dec 2011

Pfizer, Karo Bio partner to develop RORgamma modulators for autoimmune diseases

Karo Bio AB has entered into a research collaboration agreement with Pfizer Inc., to discover and develop novel small molecule RORgamma modulators for the treatment of autoimmune diseases.

26 Dec 2011

President Obama to provide federal funding for Alzheimer's programs

As the world's leading voluntary health organization advocating for Alzheimer's care, support and research, the Alzheimer's Association is pleased that Congress and President Obama have responded to calls by the Alzheimer's Association on behalf of people with Alzheimer's disease, caregivers, health professionals and researchers, to provide federal funding for several programs critical to the Alzheimer's community.

26 Dec 2011

Neuroscientists discover gene responsible for HDLS

A global team of neuroscientists, led by researchers at Mayo Clinic in Florida, have found the gene responsible for a brain disorder that may be much more common than once believed. In the Dec. 25 online issue of Nature Genetics, the researchers say they identified 14 different mutations in the gene CSF1R that lead to development of hereditary diffuse leukoencephalopathy with spheroids.

26 Dec 2011

ARV drugs can prevent transmission of HIV

The finding of a team of researchers - including several members from Johns Hopkins - that HIV treatment with antiretroviral drugs (ARVs) can actually prevent transmission of the virus from an infected person to his or her uninfected partner has been named "Breakthrough of the Year" for 2011 by the journal Science.

23 Dec 2011

Researchers reveal what cells respond to anesthesia in C. elegans

Physicians use inhalation anesthetics in a way that is incredibly safe for patients, but very little is known about the intricacies of how these drugs actually work in children and adults. Now, researchers have uncovered what cells respond to anesthesia in an organism known as the C. elegans, according to a new study from the Seattle Children's Research Institute. C. elegans is a transparent roundworm used often in research.

23 Dec 2011

Researchers successfully treat severe congenital disorder in mouse model

Using a mouse model, Heidelberg University Hospital researchers have for the first time successfully treated a severe congenital disorder in which sugar metabolism is disturbed.

23 Dec 2011

Gladstone, Bristol-Myers Squibb to identify and validate novel targets in Alzheimer's

Bristol-Myers Squibb Company and the Gladstone Institutes today announced the formation of a discovery-based research collaboration to identify and validate novel targets in Alzheimer's disease.

23 Dec 2011

Study examines prevalence of Fusarium in bathroom sink drains

A study examining the prevalence of the fungus Fusarium in bathroom sink drains suggests that plumbing systems may be a common source of human infections.

22 Dec 2011

FLT-PET imaging can effectively detect mantle cell lymphoma

Positron emission tomography (PET) and a molecular imaging agent that captures the proliferation of cancer cells could prove to be a valuable method for imaging a form of Non-Hodgkin's disease called mantle cell lymphoma, a relatively rare and devastating blood cancer.

22 Dec 2011

Researchers discover how c-MYC facilitates tumor growth

Cancer cells are essentially immortal. The acquisition of an unlimited capacity to divide - the process of immortalization - is a central event in the genesis of tumors. Normally, cells are subject to stringent mechanisms which control their proliferation. Together these ensure that pre-malignant cells are induced to enter a senescent, non-dividing state or to undergo apoptosis, i.e. commit suicide.

22 Dec 2011

CSF biomarkers can help detect early stage of Alzheimer's

Analysis of the cerebrospinal fluid can detect whether a person has Alzheimer's disease before symptoms appear. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have studied biomarkers that offer more reliable diagnosis and, in the longer term, the possibility of effective new treatments.

21 Dec 2011

CWRU receives NIDDK grant to study role of innate immunity in IBD

Investigators at Case Western Reserve University School of Medicine received a $6.75 million Program Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study the role of innate immunity in inflammatory bowel disease.

21 Dec 2011

Dieting and the youth of the brain may be linked: Study

Italian scientists have found that the mind can be kept young by eating less. They have discovered the molecular process by which a strict diet may save the brain from the ravages of age.

20 Dec 2011

IRSF announces new grants for research into Rett syndrome

The International Rett Syndrome Foundation (IRSF) announced today that it is awarding over $1.5M to support 18 new grants designed to study a variety of diverse topics from basic science and disease pathology to developing treatments and outcome measures for Rett syndrome.

20 Dec 2011