Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Transgenomic and A. Menarini Diagnostics enter distribution agreement for mutation detection systems

Transgenomic, Inc. and A. Menarini Diagnostics today announced an exclusive distribution agreement for Transgenomic's SURVEYOR Scan and WAVE MCE (Micro-Capillary Electrophoresis) Mutation Detection system to its network of over 2,000 pathologists throughout Europe.

7 Nov 2011

PKM2 enzyme has important non-metabolic functions in cancer formation

The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers. Now, a team led by researchers at the University of Texas MD Anderson Cancer Center reports in advance online publication of the journal Nature that PKM2 has important non-metabolic functions in cancer formation.

7 Nov 2011

Dual imaging approach could improve diagnosis, treatment of coronary artery disease

A new device that combines two microimaging technologies can reveal both the detailed anatomy of arterial linings and biological activities that, in coronary arteries, could indicate the risk of heart attacks or the formation of clots in arterial stents.

7 Nov 2011

Sleeping Beauty transposon system plays a vital role in investigating colorectal cancer pathway

A jumping gene with the fairy tale name "Sleeping Beauty" has helped to unlock vital clues for researchers investigating the genetics of colorectal cancer.

7 Nov 2011

University of Nebraska to honor UT Dallas director for communication research

The University of Nebraska will honor Dr. Thomas Campbell, executive director of the UT Dallas Callier Center for Communication Disorders, for a long record of research and academic achievement at the university's annual Alumni Masters Week.

4 Nov 2011

Penn research group receives NCI grant to establish BETRNet

A research group at the Perelman School of Medicine of the University of Pennsylvania, led by John Lynch, MD, PhD, assistant professor of Medicine in the Division of Gastroenterology, has received a National Cancer Institute (NCI) grant to establish a Barrett's esophagus translational research network (BETRNet) with Columbia University and the Mayo Clinic.

4 Nov 2011

Breakdown of unsaturated fats can induce complications in obese patients with acute pancreatitis

The toxic byproducts produced by the breakdown of unsaturated fats lead to a higher likelihood of severe inflammation, cell death and multi-system organ failure among acute pancreatitis patients who are obese, say researchers at the University of Pittsburgh School of Medicine.

3 Nov 2011

Increasing TR2/TR4 expression can lead to higher fetal hemoglobin levels in sickle cell patients

A University of Michigan Health System laboratory study reveals a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease.

3 Nov 2011

Role of cardiovascular magnetic resonance in clinical cardiology

Cardiovascular Magnetic Resonance (CMR) has undergone substantial development and offers important advantages compared with other well-established imaging modalities.

3 Nov 2011

Galectin Therapeutics forms Liver Fibrosis Clinical Trials Advisory Board

Galectin Therapeutics Inc., the leader in developing carbohydrate-based therapeutic compounds to inhibit galectin receptors, today announced the formation of its Liver Fibrosis Clinical Trials Advisory Board comprised of key opinion leaders from Emory Hospital and School of Medicine, Massachusetts General Hospital and Harvard School of Medicine, University of Michigan Hospital and School of Medicine, Mount Sinai Hospital and School of Medicine, and University of Wisconsin Hospital and School of Medicine.

3 Nov 2011

Ivacaftor drug improves lung function in people with cystic fibrosis

A new study has confirmed that the drug, ivacaftor (VX-770), significantly improves lung function in some people with cystic fibrosis (CF). The results of the phase III clinical trial study, "A CFTR Potentiator in Patients with Cystic Fibrosis and the G551D Mutation," led by Bonnie W. Ramsey, MD of Seattle Children's Research Institute and the University of Washington, were published today in the New England Journal of Medicine.

3 Nov 2011

Scientists identify distinct tobacco transporter for nicotine metabolism

A team of Virginia Tech and Purdue University scientists have identified a distinct transporter used by tobacco plant cells for nicotine metabolism. The research appears in the Oct. 17 online before print issue of the Proceedings of the National Academy of Sciences (PNAS) in the article, "A tobacco nicotine uptake permease effects alkaloid metabolism."

2 Nov 2011

Johns Hopkins breast cancer researcher wins BioMaryland LIFE Prize

A Johns Hopkins breast cancer researcher is the recipient of a $50,000 award designed to encourage rapid translation of her basic research on biomarkers into a commercially available test that could predict the best treatment options for some women with breast cancer.

2 Nov 2011

Glyphosine can prevent development of type 1 diabetes

Researchers at the University of Colorado School of Medicine have found a specific molecule that can prevent the development of type 1 diabetes in mice and has a similar effect on human cells from diabetic patients.

2 Nov 2011

Two transformative philanthropic gifts to fuel new discoveries at Seattle Children's

Seattle Children's today announced two transformative philanthropic gifts totaling $65 million to benefit pediatric research, nursing education and clinical care.

1 Nov 2011

National lupus organizations urge NICE to recommend Benlysta for coverage

National lupus organizations in more than 28 countries, and individuals with lupus and their families around the world, are rallying to protect access to new treatments and the development of future therapies to treat lupus.

1 Nov 2011

NPS announces new data from GATTEX Phase 3 study on short bowel syndrome

NPS Pharmaceuticals, Inc., a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, today announced new data from STEPS 2, a long-term open-label study, showing that GATTEX (teduglutide) was associated with achieving and maintaining clinically meaningful reductions in parenteral nutrition (PN) and intravenous (IV) fluid volume in adult subjects with short bowel syndrome.

1 Nov 2011

ER-positive breast cancer patients with high levels of heat shock factor 1 experience poor outcomes

Whitehead Institute scientists report that patients whose estrogen receptor (ER)-positive breast cancers have high levels of the ancient cellular survival factor heat shock factor 1 (HSF1) experience poor outcomes—including increased mortality.

1 Nov 2011

Psyche Systems and Aperio partner to provide integrated LIS and Digital Pathology solution

Psyche Systems Corporation and Aperio announced today that the companies have formed a strategic relationship which will provide customers an end-to-end integrated LIS and Digital Pathology solution.

31 Oct 2011

Gen-Probe receives FDA approval for APTIMA HPV assay

Gen-Probe Incorporated announced today that the US Food and Drug Administration (FDA) has approved its APTIMA HPV assay, an amplified nucleic acid test that detects high-risk strains of human papillomavirus (HPV) that are associated with cervical cancer and precancerous lesions.

31 Oct 2011

Pathology News and Research

Further Reading

Transgenomic and A. Menarini Diagnostics enter distribution agreement for mutation detection systems

PKM2 enzyme has important non-metabolic functions in cancer formation

Dual imaging approach could improve diagnosis, treatment of coronary artery disease

Sleeping Beauty transposon system plays a vital role in investigating colorectal cancer pathway

University of Nebraska to honor UT Dallas director for communication research

Penn research group receives NCI grant to establish BETRNet

Breakdown of unsaturated fats can induce complications in obese patients with acute pancreatitis

Increasing TR2/TR4 expression can lead to higher fetal hemoglobin levels in sickle cell patients

Role of cardiovascular magnetic resonance in clinical cardiology

Galectin Therapeutics forms Liver Fibrosis Clinical Trials Advisory Board

Ivacaftor drug improves lung function in people with cystic fibrosis

Scientists identify distinct tobacco transporter for nicotine metabolism

Johns Hopkins breast cancer researcher wins BioMaryland LIFE Prize

Glyphosine can prevent development of type 1 diabetes

Two transformative philanthropic gifts to fuel new discoveries at Seattle Children's

National lupus organizations urge NICE to recommend Benlysta for coverage

NPS announces new data from GATTEX Phase 3 study on short bowel syndrome

ER-positive breast cancer patients with high levels of heat shock factor 1 experience poor outcomes

Psyche Systems and Aperio partner to provide integrated LIS and Digital Pathology solution

Gen-Probe receives FDA approval for APTIMA HPV assay

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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