Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Analysis of non-tumor tissue may be an effective option for diagnosis of prostate cancer

Researchers have found that it may not be necessary to look for tumors directly in patients with prostate cancer - analyzing non-tumor tissue may be an effective option, according to study results published in Cancer Research, a journal of the American Association for Cancer Research.

1 Apr 2011

NCI awards Case Western Reserve with $1.6 million grant for cancer research

Case Western Reserve University School of Medicine has received a $1.6 million grant from the National Cancer Institute to study how tumor cells avoid detection by the body's immune system, allowing cancer to develop and spread.

1 Apr 2011

Basic Yellow 1 dye extends lifespan in healthy nematodes, slows Alzheimer's disease-like pathology in worms

Basic Yellow 1, a dye used in neuroscience laboratories around the world to detect damaged protein in Alzheimer's disease, is a wonder drug for nematode worms. In a study appearing in the March 30, online edition of Nature, the dye, also known as Thioflavin T, (ThT) extended lifespan in healthy nematode worms by more than 50 percent and slowed the disease process in worms bred to mimic aspects of Alzheimer's.

31 Mar 2011

Master regulators of cholesterol and fat play key role in liver fibrosis development

UCLA researchers have demonstrated that a key regulator of cholesterol and fat metabolism in the liver also plays an important role in the development of liver fibrosis - the build-up of collagen scar tissue that can develop into cirrhosis. Cirrhosis, in turn, is a major cause of premature death and is incurable without a liver transplant.

31 Mar 2011

Transgenomic discovers novel BLOCker-Sequencing technology

Transgenomic, Inc. today announced that it has discovered a novel sequencing technology, which the company has termed BLOCker-Sequencing, which enhances the limit of detection of standard Sanger Sequencing, enriches for direct sequencing of mutated DNA over wild-type and can be run on standard Sanger Sequencing equipment.

30 Mar 2011

Natural disasters can produce major lung problems

A comprehensive new review published in the journal Respirology indicates that lung problems are major causes of morbidity and mortality following natural disasters.

29 Mar 2011

CPRIT awards $36.7 million grant to UT Southwestern for cancer research

The Cancer Prevention and Research Institute of Texas has awarded more than $36.7 million in new grants to investigators at UT Southwestern Medical Center to support cancer-related projects and to recruit pre-eminent cancer investigators.

29 Mar 2011

Science Magazine reports on recent push to make preventing, treating cancer a global priority

Science Magazine reports on the recent push to make preventing and treating cancer a global priority, particularly in developing countries, where it's estimated "less than 5% of the world's cancer resources are spent."

28 Mar 2011

Scientists receive AACR Team Science Award for HPV research

The Fifth Annual AACR Team Science Award will be given to a team of internationally renowned molecular biologists, epidemiologists, biostatisticians and clinicians from Fred Hutchinson Cancer Research Center and University of Washington who have worked together on human papillomavirus for more than 20 years.

28 Mar 2011

Researchers identify genetic conspirators underlying acute myeloid leukaemia

Researchers have described how the most common gene mutation found in acute myeloid leukaemia starts the process of cancer development and how it can cooperate with a well-defined group of other mutations to cause full-blown leukaemia.

28 Mar 2011

Researchers identify new mechanism underlying MS

Multiple sclerosis is a disabling autoimmune disease in which nerve fibers are attacked by the patient's own immune system. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a new mechanism that contributes to nerve fiber damage - and shown that this damage can be reversed.

28 Mar 2011

Zileuton can help reduce amyloid plaque formation and Alzheimer's development

A drug used to treat asthma has been shown to help reduce the formation of amyloid beta, a peptide in the brain that is implicated in the development of Alzheimer's disease, according to researchers at Temple University's School of Medicine.

28 Mar 2011

Researchers identify enzyme biomarker that can diagnose early colon cancer

A research team at the University of Colorado Cancer Center has identified an enzyme that could be used to diagnose colon cancer earlier. It is possible that this enzyme also could be a key to stopping the cancer.

28 Mar 2011

CPRIT awards Bellicum $5.7 million to advance CaspaCIDe therapy for late stage cancer

Bellicum Pharmaceuticals, Inc. today announced that the Company received notice of a $5.7 million company commercialization award from the Cancer Prevention and Research Institute of Texas ("CPRIT"). Bellicum was the only company recommended for funding in this second round of the commercialization award program.

25 Mar 2011

Scientists identify protein that plays a key role in cancer treatment resistance

Research led by Daitoku Sakamuro, PhD, Assistant Professor of Pathology at LSU Health Sciences Center New Orleans and the LSUHSC Stanley S. Scott Cancer Center, has identified a protein that enables the activation of a DNA-repair enzyme that protects cancer cells from catastrophic damage caused by chemo and radiation therapy.

25 Mar 2011

Study finds gambling more common among U.S. adults than alcohol dependence

After age 21, problem gambling is considerably more common among U.S. adults than alcohol dependence, even though alcohol dependence has received much more attention, according to researchers at the University at Buffalo's Research Institute on Addictions.

25 Mar 2011

Medical experts: Nation needs to offer more confidential care for sexually active teens

After reviewing existing research regarding the common practices of health care providers who see adolescent patients across the country, Rebecca Allen, MD, MPH, a clinician and researcher at Women & Infants Hospital of Rhode Island, and her colleague, Michelle Forcier, MD, MPH, an adolescent medicine specialist at Hasbro Children's Hospital, asserted that the nation needs to offer more confidential care for teenagers who are sexually active.

25 Mar 2011

Loyola earns recognition for pathology research

Loyola University Medical Center tied for fourth place in a recent research competition for pathologists-in-training that included 100 academic medical centers worldwide.

25 Mar 2011

Researchers create new computational model to understand animal cell behavior

Biological systems, including cells, tissues and organs, can function properly only when their parts are working in harmony. These systems are often dauntingly complex: Inside a single cell, thousands of proteins interact with each other to determine how the cell will develop and respond to its environment.

24 Mar 2011

LDR submits two-level Mobi-C cervical artificial disc PMA to the FDA

LDR, a privately held medical device company offering innovative spinal implants for both non-fusion and fusion applications, announced the March 11 submission of its two-level Mobi-C cervical artificial disc PMA to the FDA. LDR is one of only two companies to have completed a two-level randomized IDE trial with two-year follow up, and is the first to submit its results.

23 Mar 2011