Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Englewood Hospital and Medical Center earns HealthGrades Patient Safety Excellence Award

Englewood Hospital and Medical Center was identified as a recipient of the 2011 HealthGrades Patient Safety Excellence Award, indicating that its patient safety ratings are in the top 5% of U.S. hospitals.

18 Mar 2011

Quest Diagnostics ColoVantage molecular colorectal cancer detection test receives New York State approval

Quest Diagnostics Incorporated, the world's leading cancer diagnostics company, today announced that its ColoVantage test has been approved by New York State's Department of Health for testing on samples of patients in the state. It is believed to be the first molecular colorectal cancer detection method that employs a venal blood specimen to be approved by the state.

From Quest Diagnostics 18 Mar 2011

Pig model reveals how cystic fibrosis gene mutation causes disease

It's been more than 20 years since scientists first discovered the gene that causes cystic fibrosis (CF), yet questions about how the mutated gene causes disease remain unanswered.

17 Mar 2011

Research highlights new parameters for HIV study

A research article co-authored by Brenna Anderson, MD, director of Reproductive Infectious Diseases Consultation in the Division of Maternal-Fetal Medicine at Women & Infants Hospital of Rhode Island, was included in the recently published special issue of the American Journal of Reproductive Immunology.

17 Mar 2011

The Lancet Neurology publishes Neurologix NLX-P101 Phase 2 trial results against PD

Neurologix, Inc., announced today that the results of the Company's Phase 2 clinical trial for its novel, investigational gene therapy NLX-P101 for the treatment of Parkinson's disease were published in an online-first edition of The Lancet Neurology.

17 Mar 2011

HPK receives Reissue Patent for digital slide scanning

Hamamatsu Photonics K.K. is pleased to announce that is has been awarded Reissue Patent No. 42,220, confirming the patentability of its original Patent 6,847,729, a pioneering patent directed to slide scanning with remote viewing.

16 Mar 2011

Enzo Life Sciences introduces ELISA system to detect SMN protein

Enzo Biochem, Inc. and the Spinal Muscular Atrophy Foundation today announced that Enzo's wholly owned subsidiary, Enzo Life Sciences Inc., has launched a unique immunoassay system which can be used for the identification and detection of Survival Motor Neuron protein.

16 Mar 2011

AYA cancer patients require targeted care, say experts

Adolescents and young adults are neither children nor adults and those affected by cancer require targeted care that crosses the boundaries between pediatric and adult oncology, according to several pioneers in this still-developing field of adolescent and young adult oncology.

15 Mar 2011

Scientists identify unique function of Twist1 in tumor metastasis

In the early stages of human embryogenesis, a transcription factor called Twist1 plays a key regulatory role in how the embryo assumes form and function. Much later in life, however, researchers at the University of California, San Diego School of Medicine, say Twist1 can re-emerge, taking a darker and more deadly turn.

15 Mar 2011

HDL cholesterol structure finding could help explain cardioprotective effects

University of Cincinnati researchers have determined the structure of human HDL cholesterol and say the finding could help explain how this "fat packet" protects against cardiovascular diseases, including heart attack and stroke.

14 Mar 2011

Combination therapy may overcome Herceptin-resistant breast cancer

Breast cancer tumors take numerous paths to resist the targeted drug Herceptin, but a single roadblock at a crucial crossroads may restore a tumor's vulnerability to treatment, scientists at The University of Texas MD Anderson Cancer Center report on line at Nature Medicine.

14 Mar 2011

CALP, HistoRx collaborate to co-develop new generation of tissue-based imaging solutions

Caliper Life Sciences, Inc. and HistoRx, Inc., today announced a collaboration to co-develop a new generation of tissue-based imaging and analysis solutions, based on immuno-fluorescence, that will deliver accurate, quantitative, and reproducible measurements of proteins in tissue samples.

11 Mar 2011

Medtronic launches VERTEX SELECT CHROMALOY Plus Rods in the U.S.

Continuing its leadership in cervical spine medical device therapies, Medtronic, Inc. today announced the U.S. launch of VERTEX SELECT CHROMALOY Plus Rods.

10 Mar 2011

Research: CREBBP mutation may help cancer resist steroid treatment, fuel ALL's return

Despite dramatically improved survival rates for childhood acute lymphoblastic leukemia, relapse remains a leading cause of death from the disease. Work led by St. Jude Children's Research Hospital investigators identified mutations in a gene named CREBBP that may help the cancer resist steroid treatment and fuel ALL's return.

10 Mar 2011

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure. sCJD is one of the causes of dementia and typically leads to death within a year of disease onset.

10 Mar 2011

Vascular disorder of the brain most frequently misdiagnosed as multiple sclerosis

A devastating vascular disorder of the brain called CADASIL, which strikes young adults and leads to early dementia, often is misdiagnosed as multiple sclerosis, Loyola University Health System researchers report.

10 Mar 2011

Vermillion's CA125 positive preliminary data against ovarian tumors presented at WCSGO

Vermillion, a molecular diagnostics company, today announced the presentation of positive preliminary data from its collaboration with Johns Hopkins University School of Medicine to identify biomarkers that improve on the specificity of CA125 for the identification of malignant ovarian tumors.

9 Mar 2011

Study supports DNA mismatch repair test for bowel cancer

Bowel cancer patients whose tumors contain defects in specific DNA repair systems are much less likely to experience tumour recurrence post surgery, results from a major clinical study have demonstrated.

9 Mar 2011

PIVI document examines endoscopic assessment of diminutive colorectal polyps

In recognition of National Colorectal Cancer Awareness Month during March, GIE: Gastrointestinal Endoscopy has put out a special issue for March on colonoscopy and colorectal cancer.

9 Mar 2011

Sanfilippo syndrome compromises blood-brain barrier, leads to brain damage

A study into the effects of Sanfilippo Syndrome type B (MPS III B) has found that the barrier responsible for protecting the brain from the entry of harmful blood-borne substances is structurally and functionally damaged by the devastating disease. University of South Florida researchers identified damage in specific brain structures involved in the pathology of MPS III B, one of four Sanfilippo syndromes, all of which are inherited diseases of metabolism.

9 Mar 2011

Pathology News and Research

Further Reading

Englewood Hospital and Medical Center earns HealthGrades Patient Safety Excellence Award

Quest Diagnostics ColoVantage molecular colorectal cancer detection test receives New York State approval

Pig model reveals how cystic fibrosis gene mutation causes disease

Research highlights new parameters for HIV study

The Lancet Neurology publishes Neurologix NLX-P101 Phase 2 trial results against PD

HPK receives Reissue Patent for digital slide scanning

Enzo Life Sciences introduces ELISA system to detect SMN protein

AYA cancer patients require targeted care, say experts

Scientists identify unique function of Twist1 in tumor metastasis

HDL cholesterol structure finding could help explain cardioprotective effects

Combination therapy may overcome Herceptin-resistant breast cancer

CALP, HistoRx collaborate to co-develop new generation of tissue-based imaging solutions

Medtronic launches VERTEX SELECT CHROMALOY Plus Rods in the U.S.

Research: CREBBP mutation may help cancer resist steroid treatment, fuel ALL's return

First disease-specific biomarker for sporadic Creutzfeldt-Jakob disease identified

Vascular disorder of the brain most frequently misdiagnosed as multiple sclerosis

Vermillion's CA125 positive preliminary data against ovarian tumors presented at WCSGO

Study supports DNA mismatch repair test for bowel cancer

PIVI document examines endoscopic assessment of diminutive colorectal polyps

Sanfilippo syndrome compromises blood-brain barrier, leads to brain damage

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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