Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Novel amyloid protein discovered from canine mammary tumors

A collaboration led by scientists at Tokyo University of Agriculture and Technology (TUAT), Japan, has discovered a novel amyloid protein from canine mammary tumors.

24 Jan 2023

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including a life-threatening fungal pneumonia.

23 Jan 2023

Senolytics could be a beneficial therapeutic for COVID neuropathology

Researchers assess the effectiveness of multiple senolytic interventions in removing senescent cells in aged human brain organoids.

22 Jan 2023

Analysis of seemingly recovered COVID-19 patients indicates that SARS-CoV-2 infection can persist significantly longer than suggested by PCR-negative tests

Scientists have described the infection dynamics and clinical features of PCR-negative patients who eventually died due to the worsening of COVID-19.

20 Jan 2023

Researchers create large-scale 2D and 3D spatial maps of colorectal cancer

In the United States, turning 45 brings with it a rather unpleasant rite of passage: the beginning of regular colonoscopies, in which an endoscope equipped with a light and a camera is used to visually check the colon for signs of cancer.

19 Jan 2023

Genotyping technology may help increase the number of kidney transplantations and reduce wait times

ABO blood-type compatibility between organ donors and recipients is crucial for safe transplantations. Across the different ABO blood groups, longer wait-times for a kidney transplant are often experienced by patients who have type B blood because it is a less common ABO blood type, resulting in fewer donors.

18 Jan 2023

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "Single-cell transcriptomics of peripheral blood in the aging mouse."

18 Jan 2023

Combination of multiple maps uncovers new genetic risk factor for AMD

Combining a map of gene regulatory sites with disease-associated loci has uncovered a new genetic risk factor of adult-onset macular degeneration (AMD), according to a new study publishing January 17th in the open access journal PLOS Biology by Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues.

18 Jan 2023

Body dissatisfaction found to be primary cause of eating disorders

Eating disorders are stereotypically associated with adolescents and young adults. Growing evidence, however, suggests that these conditions can occur at any time during a woman's lifespan, including at midlife.

18 Jan 2023

Semantic networks in the brains of schizophrenia patients found to be different from healthy individuals

In a study published last month in Schizophrenia Bulletin, researchers from Tokyo Medical and Dental University revealed that the semantic networks in the brains of schizophrenia patients are very different from those in healthy humans.

17 Jan 2023

Dementia risk in women may be reduced by hormone replacement therapy

Women are at greater risk for dementia than men, probably because of waning estrogen levels following menopause. Estrogen is a key female hormone linked to reproductive, sexual, and neurological functions. A new study published in the journal Alzheimer's Research & Therapy examines how hormone replacement works in women with a high genetic risk for AD.

17 Jan 2023

New molecular pathway critical to the initiation of pancreatic tumors discovered

Researchers at University of California San Diego School of Medicine have discovered a molecular pathway critical to the initiation of pancreatic tumors.

16 Jan 2023

Protein heat shock transcription factor 1 may be a viable therapeutic target for hepatoblastoma

Although rare compared to adult liver cancers, hepatoblastoma is the most common pediatric liver malignancy, and its incidence is increasing.

16 Jan 2023

Intranasal mRNA-lipid nanoparticle vaccines elicit significant protection against SARS-CoV-2 in hamsters

Researchers from the United States evaluated the efficacy and immunogenicity of an intranasal messenger ribonucleic acid (mRNA)-lipid nanoparticle (LNP) vaccine against SARS-CoV-2 using a hamster model.

16 Jan 2023

New blood test tracks neurodegenerative changes specifically in Alzheimer's disease

A new blood test that can track and follow the neurodegeneration in Alzheimer's disease - and exclude other dementias.

16 Jan 2023

Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

Neurodegenerative diseases affect millions of people worldwide and as our life expectancy increases, more individuals are expected to be affected in the coming decades.

16 Jan 2023

Targeting T cell iron metabolism may offer a new approach for treating lupus

Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) -; the most common form of the chronic autoimmune disease lupus.

13 Jan 2023

Valuable tool reveals the connections between gut microbes and the brain

In the past decade, researchers have begun to appreciate the importance of a two-way communication that occurs between microbes in the gastrointestinal tract and the brain, known as the gut–brain axis.

13 Jan 2023

CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain

In a recent study published in the journal Nature Neuroscience, researchers in Spain described the effectiveness of a modified vaccinia virus Ankara (MVA) vector severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidate in protecting against SARS-CoV-2 infection in the brain using a mouse model.

12 Jan 2023

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

With the growing number of skin biopsies performed annually for suspected melanoma, a simple, easily understood standardized classification system for melanocytic lesions is increasingly important to aid pathologists and clinicians who examine millions of tissue samples each year and to alleviate patient confusion and anxiety.

11 Jan 2023

Pathology News and Research

Further Reading

Novel amyloid protein discovered from canine mammary tumors

Genetic disorder that causes immunodeficiency and susceptibility to opportunistic infections discovered

Senolytics could be a beneficial therapeutic for COVID neuropathology

Analysis of seemingly recovered COVID-19 patients indicates that SARS-CoV-2 infection can persist significantly longer than suggested by PCR-negative tests

Researchers create large-scale 2D and 3D spatial maps of colorectal cancer

Genotyping technology may help increase the number of kidney transplantations and reduce wait times

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

Combination of multiple maps uncovers new genetic risk factor for AMD

Body dissatisfaction found to be primary cause of eating disorders

Semantic networks in the brains of schizophrenia patients found to be different from healthy individuals

Dementia risk in women may be reduced by hormone replacement therapy

New molecular pathway critical to the initiation of pancreatic tumors discovered

Protein heat shock transcription factor 1 may be a viable therapeutic target for hepatoblastoma

Intranasal mRNA-lipid nanoparticle vaccines elicit significant protection against SARS-CoV-2 in hamsters

New blood test tracks neurodegenerative changes specifically in Alzheimer's disease

Study identifies new tau regulators as viable therapeutic targets for Alzheimer's and other tauopathies

Targeting T cell iron metabolism may offer a new approach for treating lupus

Valuable tool reveals the connections between gut microbes and the brain

CNB-CSIC vaccine fully protects against SARS-CoV-2 infection of the brain

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

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Realizing the Importance of Medical Electronic Devices

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