Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

USA Today examines online second-opinion services

USA Today on Monday examined the use of online second-opinion services, which allow patients to receive consultations from specialists based on medical records that they fax, mail or send through the Internet

24 Jun 2008

Severe retinal hemorrhaging in young children linked to severe motor vehicle crashes

The severity of retinal hemorrhaging for young children in motor vehicle crashes is closely correlated to the severity of the crash, according to a new study by researchers at the Medical College of Wisconsin in Milwaukee. Retinal hemorrhages occur when the blood vessels lining the retina rupture, resulting in bleeding onto the surface of the retina.

24 Jun 2008

Radiation therapy prolongs life in men with recurrent prostate cancer

Men whose tumors recur after prostate cancer surgery are three times more likely to survive their disease long term if they undergo radiotherapy within two years of the recurrence. Surprisingly, survival benefits were best in men whose new tumors were growing fastest, according to results of a 'look-back' study of 635 men by Johns Hopkins Medical Institutions researchers reported June 18 in the Journal of the American Medical Association.

17 Jun 2008

Fluorescent-probe in worm creates real-time "view" of cellular stress

Scientists at the University at Buffalo have created a mutant worm that changes color when it moves. The color change is generated by an optical sensor called stFRET. The sensor is composed of a pair of fluorescent molecules connected by a molecular spring that is inserted into structural proteins in the worm's cells.

16 Jun 2008

Genetic variation linked to earlier onset of Alzheimer's symptoms

Investigators at Washington University School of Medicine in St. Louis have identified a genetic variation associated with an earlier age of onset in Alzheimer's disease.

9 Jun 2008

Majority of U.S. House supports repeal of Medicare therapy caps

With about one month to go before the current exceptions process for clinically based care above the Medicare therapy caps expires, a majority of the U.S. House of Representatives has endorsed legislation to repeal the arbitrary financial limit on therapy benefits.

5 Jun 2008

New molecular mechanism for colorectal cancer

Scientists in Portugal just found a new molecular mechanism behind colorectal cancer in which a mutated and a normal, but over-expressed, gene cooperate and are both needed to create the disease.

4 Jun 2008

Study investigates mental and physical effects of collective traumas

Contrary to popular notions about what is normal or healthy, new research has found that it is okay not to express one's thoughts and feelings after experiencing a collective trauma, such as a school shooting or terrorist attack.

1 Jun 2008

Estrogen drives distinct, aggressive prostate cancer

Using a breakthrough technology, researchers led by a Weill Cornell Medical College scientist have pinpointed the hormone estrogen as a key player in about half of all prostate cancers.

28 May 2008

Why some treatments rescue aging skin

Fine wrinkles, deeper creases, saggy areas around the mouth and neck - the sights in the mirror that make baby boomers wince - are not inevitable. They result from a structural breakdown inside the skin that some existing treatments effectively counteract by stimulating the growth of new, youthful collagen, University of Michigan scientists say.

28 May 2008

Embryonic pathway delivers stem cell traits

Studies of how cancer cells spread have led to a surprising discovery about the creation of cells with adult stem cell characteristics, offering potentially major implications for regenerative medicine and for cancer treatment.

25 May 2008

High resolution confocal endomicroscopy probe system tells whether colon polyp is benign without removal

A probe so sensitive that it can tell whether or not a cell living within the human body is veering towards cancer development may revolutionize how future colonoscopies are done, say researchers from the Mayo Clinic in Jacksonville, Fla.

21 May 2008

Unique genetic signature alerts physicians to high-risk breast tumors

A unique genetic signature can alert physicians to high-risk breast tumors that are masquerading as low-risk tumors, according to research at Washington University School of Medicine in St. Louis and collaborating institutions. Although these tumors are apparently estrogen-receptor positive - meaning they should depend on estrogen to grow - they don't respond well to anti-estrogen therapy.

21 May 2008

Chemically modified protein may help people with hard-to-treat hemophilia

Pathologists at The University of Texas Health Science Center at Houston have developed a chemically modified protein that may help people with a hard-to-treat form of a genetic bleeding disorder known as Hemophilia A. The discovery and the results of pre-clinical tests appear in the May 2 issue of the Journal of Biological Chemistry.

19 May 2008

Rochester vaccine triggers immune response, prevents Alzheimer's

A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer's disease-like pathology in mice without causing inflammation or significant side effects.

19 May 2008

Length of telomeres in blood cells tied to breast cancer survival rates

Researchers at Umea University in Sweden have shown that the length of telomeres in blood cells in newly diagnosed breast cancer patients is tied to survival rates. The study, published in the journal Cancer Research, was carried out by a research team headed by Professor Goran Roos at the Department of Medical Bioscience, Pathology.

15 May 2008

New Wilmot Cancer Center offers expanded care, research for cures

The University of Rochester Medical Center (URMC) today celebrates the expansion of cancer care and research as it dedicates the new James P. Wilmot Cancer Center. The Center introduces leading-edge technology, greater access to multidisciplinary care, a new model for breast care, and more opportunities to receive tomorrow's therapies today.

15 May 2008

Molecular clock could predict risk for developing breast cancer

A chemical reaction in genes that control breast cancer provides a molecular clock that could one day help researchers more accurately determine a woman's risk for developing breast cancer and provide a new approach for treatment, UT Southwestern Medical Center researchers have found.

15 May 2008

Arsenic-based agent shown to help eradicate leukemia-initiating cells

In both leukemia and solid tumors, there exists among the multitude of warrior cancer cells a small subgroup that work undercover, patiently lying in wait to launch their attacks. Known as either cancer initiating cells (CICs) or leukemia initiating cells (LICs), these stealth populations are impervious to conventional chemotherapy and undaunted by targeted cancer therapies. When a leukemia patient relapses following a period of remission, it is the LICs that bear responsibility for the disease's reemergence.

12 May 2008

Researchers step closer to finding ways to treat type 1 diabetes

Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.

9 May 2008