Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Blood test to detect ovarian cancer using three proteins found in common in the blood of women with the disease

Their preliminary studies with the new test suggest a molecular signature exclusive to this deadly cancer, known for its ability to remain undetected and spread quickly.

15 Aug 2004

Red wine is much better for you than gin

Red wine contains many complex compounds including polyphenols, which are absent from gin. They found that drinking red wine had a much greater effect in lowering levels in the bloodstream of so-called “anti-inflammatory” substances that are risk factors in the development of heart disease and stroke.

12 Aug 2004

New treatment strategy for brain cancer

Virginia Commonwealth University Massey Cancer Center researchers have found that combining ionizing radiation with a secreted protein that selectively inhibits tumor cell growth and survival can target cancer cells and leave healthy cells alone, perhaps presenting a new approach for treating the deadliest type of brain tumor.

9 Aug 2004

Possible role for BK virus in development of prostate cancer

Now, new research by scientists at the University of Michigan Medical School suggests the intriguing possibility that this common virus also may play a role in prostate cancer – the second-leading cause of deaths from cancer in American men.

9 Aug 2004

Recommendation against the use of chemotherapy sensitivity and resistance assays

A new technology assessment from the American Society of Clinical Oncology states that the use of chemotherapy sensitivity and resistance assays (CSRAs) to select chemotherapeutic agents for cancer patients should not be undertaken outside of the clinical trial setting.

3 Aug 2004

Isolated soy protein shown to benefit type 2 diabetics

Isolated soy protein added to the diets of 14 men, all military veterans under treatment for advanced stages of type 2 diabetes, significantly lowered unwanted proteins in their urine and slightly raised desired HDL cholesterol levels in their blood, researchers say.

2 Aug 2004

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Hotspots in two areas of a gene that encodes a specific signaling enzyme, or kinase, are vulnerable to a variety of mutations found in five types of brain cancers, according to a report published in the August 1 issue of the journal Cancer Research.

2 Aug 2004

Misfiring proteins linked to sick feeling of type 2 diabetics

After a series of studies in the laboratory of Dr. Gregory Freund, a clearer picture is emerging: A disruption of signaling proteins in the immune system may be responsible for the inflammation that makes someone with type 2 diabetes feel sick and increases the risk of serious complications.

29 Jul 2004

One of the world’s most sophisticated systems for keeping electronic health records

The system, called VistA-Office Electronic Health Record, was developed by VA. A version of VistA is used at more than 1,300 VA facilities throughout the United States to maintain records on 5 million veterans who receive their health care from VA.

23 Jul 2004

Preliminary tests of the new method, which can detect cancer in a sample with as few as 50 cells

Finding cancer in a tiny drop of body fluid containing relatively few cells now may be possible with a new method of analyzing multiple genes in small samples of DNA, the cellular building blocks of our genetic code.

23 Jul 2004

Stress found to be associated with hyperprolactinemia

A group of Italian investigators headed by Nicoletta Sonino (University of Padova) has performed the first controlled investigation on the relationship between stressful life events and an endocrine disease characterized by increased prolactin levels (hyperprolactinemia).

21 Jul 2004

Research may help predict risk for prostate cancer based on gene expression patterns

According to a study published in the July 15 issue of the Journal of Clinical Oncology, genes expressed in benign tissue adjacent to prostate cancer tissue are much more similar to those expressed in prostate cancer tissue than previously thought.

15 Jul 2004

Becoming a proficient doctor has always demanded hard work; it is unacceptable to leave out large parts of the curriculum

The current fashion in teaching doctors, which allows medical students to decide what they want to learn and how to go about it, is strongly criticised in a paper published in the British Medical Journal this week (10th July 2004).

8 Jul 2004

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

Researchers at the University of California, San Diego (UCSD) School of Medicine have determined that a particular type of cellular stress called osmotic stress is of critical importance to cell growth and the body’s immune response against infection.

7 Jul 2004

The impact of rotavirus on the world’s children

With vaccines against the killer disease of rotavirus almost in hand, government representatives, scientists, public health professionals and vaccine industry representatives will be convened in Mexico City to review progress toward safe, effective rotavirus vaccines and address the question of how to make sure they get to the world’s poorest children

7 Jul 2004

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Treatment with a new dual cell cycle and angiogenesis pathway inhibitor blocks VEGF-induced vascular permeability, inhibits tumour angiogenesis and induces apoptosis in human tumour models

7 Jul 2004

Pathology News and Research

Further Reading

Blood test to detect ovarian cancer using three proteins found in common in the blood of women with the disease

Red wine is much better for you than gin

New treatment strategy for brain cancer

Possible role for BK virus in development of prostate cancer

Recommendation against the use of chemotherapy sensitivity and resistance assays

Isolated soy protein shown to benefit type 2 diabetics

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Misfiring proteins linked to sick feeling of type 2 diabetics

One of the world’s most sophisticated systems for keeping electronic health records

Preliminary tests of the new method, which can detect cancer in a sample with as few as 50 cells

Stress found to be associated with hyperprolactinemia

Research may help predict risk for prostate cancer based on gene expression patterns

Becoming a proficient doctor has always demanded hard work; it is unacceptable to leave out large parts of the curriculum

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

The impact of rotavirus on the world’s children

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Broadband technology for medical professionals in rural Australia

A new protocol for bone marrow transplants

Celiac disease may affect 3 million Americans, ten times higher than previous estimates

U-M scientists say Wnt protein prevents obesity by inhibiting fat cell development

Snapping at new biotech breakthroughs with Gator Pro

Realizing the Importance of Medical Electronic Devices

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