Pathophysiology News and Research

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Study explores biological marker to predict individual response to drug treatment for combat PTSD

Treatment with the drug prazosin effectively reduces symptoms of posttraumatic stress disorder (PTSD) for many people, but about one third of patients don't respond to the treatment at all.

5 Nov 2016

New study to explore therapeutic pill for treatment of concussion

The goal of finding a treatment for concussion may be one step closer due to a new study being launched by University of Miami researchers.

1 Nov 2016

Study offers clues to help develop new treatments for cannabis use disorder

A new paper in Biological Psychiatry reports that chronic cannabis users have reduced levels of an enzyme called fatty acid amide hydrolase (FAAH).

25 Oct 2016

New imaging method helps observe activation of neural circuits in the brain

Watching millions of neurons in the brain interacting with each other is the ultimate dream of neuroscientists! A new imaging method now makes it possible to observe the activation of large neural circuits, currently up to the size of a small-animal brain, in real time and three dimensions.

14 Oct 2016

Researchers confirm long persistence of Zika virus in semen and reveal its presence within spermatozoa

Recent work has shown that Zika virus persists in semen for up to 6 months after infection. In a correspondence published in The Lancet Infectious Diseases, the researchers, in addition to confirming its long persistence in semen (in this case for more than 130 days, i.e., over 4 months), reveal the presence of the virus even within spermatozoa.

4 Oct 2016

CCN article outlines unique treatment options for cardiovascular patients with HIV

Cardiovascular disease has become the leading cause of death for those living with HIV, as the infection has moved from a terminal disease to a chronic illness.

3 Oct 2016

Graded aerobic treadmill testing safe, tolerable in young patients with sports-related concussion

Graded aerobic treadmill testing is safe, tolerable, and useful in evaluating and managing cases of sports-related concussion in children and adolescents.

3 Oct 2016

Scientists establish new framework for studying psychiatric pathology

The case-control method, where researchers compare patients with a particular disease to healthy control participants, has increased understanding of disease-related effects at a group level.

30 Sep 2016

ATA announces winner of John B. Stanbury Thyroid Pathophysiology Medal

The American Thyroid Association will present the John B. Stanbury Thyroid Pathophysiology Medal to Kenneth D. Burman, M.D. at the ATA's 86th Annual Meeting, September 21-25, 2016, in Denver, Colorado.

21 Sep 2016

Study finds South Africans living with HIV more resilient despite chronic pain

When one thinks about chronic conditions that are commonly painful, HIV doesn't typically spring to mind. However, more than 50% of HIV-positive individuals experience a painful condition like headache, chest pain or neuropathy, and that pain is frequently experienced as moderate to severe in intensity.

14 Sep 2016

Graded aerobic treadmill testing useful in evaluating sports-related concussion in children

Graded aerobic treadmill testing is safe, tolerable, and useful in evaluating and managing cases of sports-related concussion in children and adolescents.

13 Sep 2016

Learning to downregulate amygdala activity could help gain control of emotional responses

Training the brain to treat itself is a promising therapy for traumatic stress. The training uses an auditory or visual signal that corresponds to the activity of a particular brain region, called neurofeedback, which can guide people to regulate their own brain activity.

12 Sep 2016

New vaccine against grass pollen allergies may help combat hepatitis B infection

A new type of vaccine against grass pollen allergies (BM32) might also offer an effective treatment for combating hepatitis B infection.

8 Sep 2016

Drug-eluting stents more beneficial to patients undergoing saphenous vein graft angioplasty

Drug-eluting stents had a clear advantage over bare metal stents in patients undergoing revascularisation of saphenous (leg) vein grafts, results of the BASKET-SAVAGE trial show.

30 Aug 2016

New research may explain why people with blood group O get more severely ill from cholera

People with blood type O often get more severely ill from cholera than people of other blood types. New research from Washington University School of Medicine in St. Louis may explain why.

29 Aug 2016

Researchers explore molecular mechanisms through which lead exposure may affect neural stem cells

Researchers have identified a potential molecular mechanism through which lead, a pervasive environmental toxin, may harm neural stem cells and neurodevelopment in children.

26 Aug 2016

Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Patients with sickle cell anemia (SCA) develop heart complications and nearly a quarter die a sudden death. Now, researchers have linked malfunctioning molecular pathways to specific heart anomalies in SCA that result from progressive fibrosis and result in sudden death.

9 Aug 2016