Pathophysiology News and Research

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Low levels of vitamin D associated with poorer lung function in children with STRA

Children with severe therapy-resistant asthma (STRA) may have poorer lung function and worse symptoms compared to children with moderate asthma, due to lower levels of vitamin D in their blood, according to researchers in London.

23 Sep 2011

Tips for recognizing stroke symptoms

Drs. Savita Khanna and Cameron Rink, both assistant professors of surgery in the College of Medicine at The Ohio State University Medical Center are part of a research team that has been working for more than a decade to identify ways to reduce brain injury during stroke.

21 Sep 2011

NeuroVive, Selcia sign research collaboration agreement to develop new mitochondrial drugs

UK-based contract research organisation Selcia Limited and Swedish drug development company NeuroVive Pharmaceutical AB have signed a significant research collaboration agreement to develop new medicines and drug compounds targeting mitochondrial physiology and pathophysiology.

19 Sep 2011

U of C researchers create new model of obsessive-compulsive disorder

A new model of obsessive-compulsive disorder (OCD) that mirrors both symptoms of the disease and the timing of its treatment in humans has been created by University of Chicago researchers, according to a new study.

16 Sep 2011

APS sponsors 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels

The American Physiological Society is sponsoring the 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels, being held September 18-22 at the Asilomar Conference Grounds in Pacific Grove, Calif. This scientific conference explores the connection between fluid balance in the body and hypertension, a growing global health concern.

8 Sep 2011

Researchers rethink fenretinide for prevention of oral cancer

Scientists on the cutting edge of biomedical research know that research is a process - a combination of successes and failures that inform the next step forward. However, for some researchers at The Ohio State University progress means taking a step back. Supported by the Ohio State University Center for Clinical and Translational Science (CCTS), these scientists are using failed and forgotten research to uncover future treatments for major health conditions as diverse as oral cancer and stroke.

7 Sep 2011

New blood test could help identify babies at risk of sickle cell disease

A new blood test is being developed by researchers in Cambridge and Oxford, which, for the first time, could help identify babies at risk of a severe form of sickle cell disease, allowing immediate and more intensive treatment to be given, thanks to a grant from children's charity Action Medical Research.

7 Sep 2011

New Diabetes Care article helps to identify and treat Charcot foot

Robert Winkler says he limped around on his painful left foot for six months, suffering unnecessarily from a misdiagnosis by a physician who didn't know about the symptoms and treatments for Charcot foot, a form of localized osteoporosis linked to diabetes that causes the bones to soften and break, often resulting in amputation.

2 Sep 2011

Risk of depression in formerly depressed people

Depression is increasingly recognized as an illness that strikes repeatedly over the lifespan, creating cycles of relapse and recovery. This sobering knowledge has prompted researchers to search for markers of relapse risk in people who have recovered from depression. A new paper published in Elsevier's Biological Psychiatry suggests that when formerly depressed people experience mild states of sadness, the nature of their brains' response can predict whether or not they will become depressed again.

22 Aug 2011

Elsevier adds 'Two Years and Counting' white paper, updated eBook to ICD-10 Roadmap

Elsevier / MC Strategies, a pioneer in providing eLearning solutions to more than 1,300 healthcare organizations, today announced the addition of a white paper, "Two Years and Counting", as well as updates to its eBook, A Guide to Education and Training for ICD-10 Implementation, to its ICD-10 Roadmap.

9 Aug 2011

Promising compounds for new anti-obesity drugs

Though it generally is known that obesity dramatically increases the risk for type 2 diabetes, the biological mechanisms for that connection still are unclear.

21 Jul 2011

People with small hippocampus do not face higher risk of depression

Imaging studies have repeatedly found that people with depression have smaller hippocampal volumes than healthy individuals. The hippocampus is a brain region involved in learning and memory, spatial navigation, and the evaluation of complex life situations or "contexts".

20 Jul 2011

Air traffic pollution impacts growth and development of unborn children

A UK academic is calling for a nationwide study into the effects traffic pollution has on asthma sufferers after his own research in Cairo highlighted health problems in children who may even be affected while still in the womb.

6 Jul 2011

Positive results from RISE and RIDE Phase III trials of Genentech's Lucentis for diabetic macular edema

Genentech, a member of the Roche Group, today announced 24-month results from the two pivotal Phase III trials (RISE and RIDE) assessing the efficacy and safety of Lucentis (ranibizumab injection) in people with diabetic macular edema (DME).

29 Jun 2011

Vitamin D supplements safe for healthy pregnant women

Use of vitamin D supplements during pregnancy has long been a matter of concern but now researchers writing in the Journal of Bone and Mineral Research report that even a high supplementation amount in healthy pregnant women was safe and effective in raising circulating vitamin D to a level thought by some to be optimal. The study also found no adverse effects of vitamin D supplementation, even at the highest amount, in women or their newborns.

27 Jun 2011

University of Virginia professor speaks about gender disparity in abdominal aortic aneurysms

At the 65th Vascular Annual Meeting of the Society for Vascular Surgery, Gilbert R. Upchurch, Jr., MD from the division of thoracic and cardiovascular surgery at University of Virginia Health System in Charlottesville, spoke about gender differences in abdominal aortic aneurysms.

18 Jun 2011

Men with migraine suffer from PTSD than women

A recently published paper highlights that while the risk of post-traumatic stress disorder (PTSD) is more common in those with migraine than those without migraine irrespective of sex, the risk is greater in male migraineurs than female migraineurs. Study details are now available in Headache: The Journal of Head and Face Pain, published by Wiley-Blackwell on behalf of the American Headache Society.

1 Jun 2011

Appendix and tonsil surgeries before age 20 can increase risk of premature heart attack

The surgical removal of the appendix and tonsils before the age of 20 was associated with an increased risk of premature heart attack in a large population study performed in Sweden. Tonsillectomy increased the risk by 44% (hazard ratio 1.44) and appendectomy by 33% (HR 1.33).

1 Jun 2011

EURETINA honors Retina Implant founder with Innovation Award in the field of artificial vision

Retina Implant AG today announced that the Company's founder Professor Eberhart Zrenner M.D. was awarded the second prize by The European Society for Retina Specialists.

31 May 2011

Statins can help reduce lung damage in severe abdominal sepsis

Statins may be best known for their ability to reduce cholesterol, but a research report appearing in the May 2011 issue of the Journal of Leukocyte Biology shows that these same drugs could also play a crucial role in the reduction of lung damage resulting from severe abdominal sepsis and infection.

3 May 2011