Peripheral Artery Disease News and Research

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Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.

High prevalence and risks of heart failure warrant urgent action, say researchers

Up to 2% of adults in Europe, North America, and Israel likely have heart failure, and are at high risk of death and additional serious complications, suggest current estimates based on digital health records for 11 countries, and published online in the journal Heart.

14 Feb 2023

Two cardiovascular drugs may help improve outcomes for patients who experienced small vessel stroke

A study of two widely used cardiovascular medications — cilostazol and isosorbide mononitrate — in more than 350 patients confirmed the two medications were well-tolerated and safe for people who have experienced a stroke in a small blood vessel deep in the brain.

13 Feb 2023

Non-esterified fatty acid levels correlate with peripheral artery disease risk

Researchers investigate the association between non-esterified fatty acids and incident clinical peripheral artery disease in older adults.

2 Feb 2023

Knowing your cholesterol level can be a crucial factor in overall health

On a top 10 list of things to do, getting your cholesterol level checked likely doesn't make the cut – but no matter your age, knowing your numbers can be a crucial factor in overall health.

2 Feb 2023

COVID pandemic caused cardiovascular deaths to rise sharply

A recent report by the American Heart Association published in the journal Circulation reported the updated statistics on the major circulatory and cardiovascular diseases, and their outcomes for 2023, with additional insights into the trends in heart disease during the coronavirus disease 2019 (COVID-19) pandemic.

29 Jan 2023

Transient ischemic attack needs emergency assessment to help prevent a full-blown stroke

Stroke symptoms that disappear in under an hour, known as a transient ischemic attack (TIA), need emergency assessment to help prevent a full-blown stroke, according to a new American Heart Association scientific statement published today in the Association's journal Stroke.

19 Jan 2023

Acquired mutations in 'Guardian of the Genome' accelerate the development of atherosclerosis

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in collaboration with institutes in the USA, has demonstrated that acquired mutations in the gene encoding the protein p53 contribute to the development of atherosclerotic cardiovascular disease.

16 Jan 2023

Good hydration may slow down aging and prolong disease-free life

Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine.

2 Jan 2023

New scientific statement highlights the impact of telehealth in cardiovascular disease management

Telehealth is a proven and valuable option for people with cardiovascular disease, however, there are limitations to its use in rural and under-resourced communities, according to a new scientific statement from the American Heart Association, published today in the Association's flagship peer-reviewed journal Circulation.

14 Nov 2022

Restoring blood flow to the legs reduces pain, improves quality of life for people with peripheral artery disease

Restoring blood flow to the legs, whether through bypass surgery or a less invasive artery-opening procedure with a stent, reduced pain and improved quality of life for people with peripheral artery disease (PAD), according to preliminary, late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Bypass surgery linked to fewer amputations in people with severe peripheral artery disease

People with severe peripheral artery disease, or PAD, who received bypass surgery to improve blood flow to their legs and feet had 65 percent fewer repeat procedures and 27% fewer amputations than those who had minimally invasive procedures such as angioplasty and stenting, according to preliminary late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

Performing open bypass surgery to restore circulation for people with a severe form of peripheral artery disease (PAD) – a condition that limits blood flow to the legs and feet – resulted in better outcomes for specific patients compared to a less-invasive procedure, a National Institutes of Health-supported clinical research trial has found.

7 Nov 2022

New approach provides better understanding of atherosclerosis in the leg arteries

Cardiovascular experts at UVA Health have found a new way to track peripheral artery disease (PAD), a serious medical condition involving atherosclerosis in the leg arteries that affects more than 200 million people worldwide.

26 Sep 2022

Research highlights the serious health implications of young-onset type 2 diabetes

Men and women who are diagnosed with type 2 diabetes (T2D) aged 40 or younger are far more likely to develop cardiovascular disease (CVD) and die prematurely than those under 40 in the general population, according to new research to be presented at this year's European Association for the Study of Diabetes (EASD) Annual Meeting in Stockholm, Sweden (19-23 Sept).

7 Sep 2022

What is the association between COVID-19 and thrombotic events?

In a new study, researchers assessed the association of COVID-19 and influenza with thrombotic events among patients.

18 Aug 2022

Exercise that induces leg pain seems to be beneficial for people with peripheral artery disease

Walking for exercise at a pace that induced pain or discomfort improved walking ability among people with peripheral artery disease, or PAD, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

27 Jul 2022

Smoking increases risk of severe COVID-19 outcomes in hospitalized patients

New research assessed the association of smoking with COVID-19 complications.

20 Jul 2022

The past, present and future of aspirin in cardiovascular disease prevention

The International Aspirin Foundation A special edition issue of the Aspirin Summaries has been published '125 years of aspirin - the role of aspirin in CVD' issue 2022 .

29 Jun 2022

Study finds no difference in survival between patients treated with paclitaxel drug-coated devices and non-DCDs

New long-term data from the Safety Assessment of Femoropopliteal Endovascular Treatment With PAclitaxel-coated Devices (SAFE-PAD) study were presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2022 Scientific Sessions.

20 May 2022

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

Nearly half of heart disease patients have insomnia, according to research presented at ESC Preventive Cardiology 2022, a scientific congress of the European Society of Cardiology, and published in SLEEP Advances.

7 Apr 2022

Peripheral Artery Disease News and Research

High prevalence and risks of heart failure warrant urgent action, say researchers

Two cardiovascular drugs may help improve outcomes for patients who experienced small vessel stroke

Non-esterified fatty acid levels correlate with peripheral artery disease risk

Knowing your cholesterol level can be a crucial factor in overall health

COVID pandemic caused cardiovascular deaths to rise sharply

Transient ischemic attack needs emergency assessment to help prevent a full-blown stroke

Acquired mutations in 'Guardian of the Genome' accelerate the development of atherosclerosis

Good hydration may slow down aging and prolong disease-free life

New scientific statement highlights the impact of telehealth in cardiovascular disease management

Restoring blood flow to the legs reduces pain, improves quality of life for people with peripheral artery disease

Bypass surgery linked to fewer amputations in people with severe peripheral artery disease

Open bypass surgery results in better outcomes for specific patients with severe form of peripheral artery disease

New approach provides better understanding of atherosclerosis in the leg arteries

Research highlights the serious health implications of young-onset type 2 diabetes

What is the association between COVID-19 and thrombotic events?

Exercise that induces leg pain seems to be beneficial for people with peripheral artery disease

Smoking increases risk of severe COVID-19 outcomes in hospitalized patients

The past, present and future of aspirin in cardiovascular disease prevention

Study finds no difference in survival between patients treated with paclitaxel drug-coated devices and non-DCDs

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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