Phenotype News and Research

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Stanford study finds genetic similarities among species that use sound waves to navigate

Insect-eating bats navigate effortlessly in the dark and dolphins and killer whales gobble up prey in murky waters thanks in part to specific changes in a set of 18 genes involved in the development of the cochlear ganglion -- a group of nerves that transmit sound from the ear to the brain, according to a study by researchers at Stanford University.

4 Oct 2019

New test could improve outcomes for patients with sepsis

A new test to determine whether antibiotics will be effective against certain bacterial infections is helping physicians make faster and better prescription treatment choices.

3 Oct 2019

New mechanism that controls DNA repair identified

Deoxyribonucleic acid (DNA), is the macromolecule that holds all hereditary and genetic information. Continuously under assault, alterations and damage to DNA can lead to many different health issues, including cancer.

2 Oct 2019

Study may lead to earlier detection of heart failure and new targeted treatments

Genetic research led by Queen Mary University of London could open the way to earlier identification of people at risk of heart failure and to the development of new treatments.

26 Sep 2019

Scientists reveal how typhoid toxin works to accelerate aging of cells

Scientists have revealed how the typhoid toxin works to hijack DNA repair machines and accelerate the aging of cells, a breakthrough that could pave the way for new strategies to combat the killer disease.

6 Sep 2019

Discovery of second gene responsible natural short-sleep

Sleep is a crucial part of human health. Piling up a chronic sleep debt by consistently sleeping less than is needed for a fully rested feeling causes a number of illnesses, including heart disease, cancer and autoimmune conditions.

1 Sep 2019

MUSC researchers narrow down risk of preeclampsia to a specific phenotype

The force of blood traveling through your arteries and veins determines much of your heart health. High blood pressure can lead to heart disease, heart failure, heart attack, stroke and chronic kidney disease, and when it's coupled with type 1 diabetes and pregnancy, it can put both the mother and the baby at risk.

29 Aug 2019

New study helps explain why lung tumors turn aggressive

Lung cancer is the number 1 killer among cancers, especially when it is of the non-small cell type. Among these, adenocarcinomas are the most common and aggressive type. These tumors also show a strong tendency to show dedifferentiation, or loss of the features that characterize a mature lung cell.

28 Aug 2019

Lipid signaling pathway may enhance T cell-mediated immunotherapy

The immune system surveils our body looking for things that don't belong, often bacteria and viruses. While cancer cells are abnormal cells that undergo unregulated cell growth, they are good at evading detection by the immune system.

19 Aug 2019

Researchers describe histological features of urinary obstruction in humans for the first time

A research group from the Medical University of Vienna has successfully described the histological features of urinary obstruction in humans the first time.

13 Aug 2019

New insights into emergent evolutionary potential and generative phenotype

In the cover photo, nature photographer Andreas Kay has captured one of the most striking examples of Batesian Mimicry in nature--first reported by Henry Walter Bates in 1861.

9 Aug 2019

New improved model for cancer wasting syndrome cachexia

A new model of cancer-related cachexia promises to help scientists understand why patients with cancer show severe wasting, which in turn may drive the development of better therapies.

7 Aug 2019

New mouse model could lead to a better understanding of cachexia syndrome

A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidences in pancreatic cancer patients.

6 Aug 2019

Researchers open up possible avenue for new cancer treatments without side effects

Researchers have opened up a possible avenue for new cancer therapies that don't have the side effects that oftentimes accompany many current cancer treatments by identifying a protein modification that specifically supports proliferation and survival of tumor cells.

6 Aug 2019

Researchers use paper-based structures to mimic layered nature of aortic valves

Paper is at the heart of an experimental device developed by Rice University bioengineers to study heart disease.

6 Aug 2019

Early neuroimaging essential for Zika-exposed infants

Seventy-one of 110 Brazilian infants at the highest risk for experiencing problems due to exposure to the Zika virus in the womb experienced a wide spectrum of brain abnormalities, including calcifications and malformations in cortical development, according to a study published July 31, 2019 in JAMA Network Open.

31 Jul 2019

MGH study shows the importance of fatty acid balance in chronic disease

Using novel transgenic mouse models they developed, Massachusetts General Hospital investigators have provided new evidence that it is the ratio of omega-6 and omega-3 fatty acids, rather than the total amount of them, that influences risk of developing chronic disease.

27 Jul 2019

UTA scientists part of NIH-funded study of precision therapy for HFpEF patients

Nearly half of all heart failure patients do not have effective treatments for their condition, so three researchers at The University of Texas at Arlington are taking a more precise approach.

23 Jul 2019

Study examines role of plastic exposure in irregular heart rhythms, arrhythmias

Calling an ambulance during an emergency, emailing a breaking news or journal article before a 5 p.m. deadline and maintaining conditions during the fifth week of a 6-week lab study, without altering the light or temperature, requires electricity and translates into time, money and lives

22 Jul 2019