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Elsevier assumes publication of Neoplasia and Translational Oncology journals

Elsevier, a world-leading provider of scientific, technical and medical information products and solutions, has announced that it has acquired Neoplasia Press Inc. and assumes publication of its flagship journals, Neoplasia and Translational Oncology. These peer-reviewed, open access journals are now published by Elsevier under the Neoplasia Press imprint.

6 Jan 2015

Different gene mutations lead to different features of ASD

People with autism have a wide range of symptoms, with no two people sharing the exact type and severity of behaviors.

23 Dec 2014

Mexican study shows mobility can be restored in patients with Parkinson's disease

Mexican scientists demonstrated experimentally, with adult rats, that mobility can be restored in patients with Parkinson's disease, the major degenerative disease of the motor system worldwide.

22 Dec 2014

Chromosome X microduplications implicated in infancy-onset gigantism

Researchers report that heritable microduplications on chromosome Xq26.3 may underlie a “striking” form of gigantism with onset in late infancy, and reveal a candidate culprit gene.

22 Dec 2014

Researchers reveal common features responsible for antibiotic resistance

Treating bacterial infections with antibiotics is becoming increasingly difficult as bacteria develop resistance not only to the antibiotics being used against them, but also to ones they have never encountered before. By analyzing genetic and phenotypic changes in antibiotic-resistant strains of E. coli, researchers at the RIKEN Quantitative Biology Center in Japan have revealed a common set of features that appear to be responsible for the development of resistance to several types of antibiotics.

18 Dec 2014

Psychotic experiences show shared genetic liability

Study findings provide support for psychotic experiences being an early marker of increased risk of psychosis transition and an important intermediary phenotype in transdiagnostic research on psychosis.

11 Dec 2014

Study provides insights into genetic underpinnings of childhood epilepsies

Technological advances in genetic analysis have uncovered changes in single genes that account for a surprising number of infantile and early-childhood epilepsies. Though some of the affected genes have been identified, the physical manifestations of these alterations remain largely uncharacterized.

7 Dec 2014

Stable asthma prevalence masks increase in allergic phenotype

The prevalence of childhood asthma in Sweden appears to have stabilised, with no increase seen between 1996 and 2006, researchers report.

25 Nov 2014

SRY protein alters specific gender-related tissue in males before birth

Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges.

21 Nov 2014

Researchers develop diagnostic tool to examine traveling cancer cells, improve health outcomes

For most cancer patients, primary tumours are often not the most deadly. Instead, it is the metastatic tumours - tumours that spread from their original location to other parts of the body - that are the cause of most cancer deaths.

6 Nov 2014

Study suggests possible link between body fat and risk of immunotherapy toxicity

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found.

4 Nov 2014

UC Davis researchers link increased body fat and lethal drug reactions in mice

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. The findings, published online today in The Journal of Experimental Medicine, suggest a possible link between body fat and the risk of toxicity from some types of immunotherapy.

3 Nov 2014

Severe childhood asthma linked to COPD in adult life

Children with severe asthma are at an increased risk of developing chronic obstructive pulmonary disease in adult life, show findings of an Australian study.

31 Oct 2014

Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Investigators at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center will present their latest aging research at the Gerontological Society of America's 67th Annual Scientific Meeting.

31 Oct 2014

Antibiotic-resistant bacteria share resources to cause chronic infections, show studies

Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt University investigators have discovered.

20 Oct 2014

Whole exome sequencing can assist in early diagnosis of various disorders

Approximately one-fourth of the 3,386 patients whose DNA was submitted for clinical whole exome testing received a diagnosis related to a known genetic disease, often ending a long search for answers for them and their parents, said researchers from the Baylor College of Medicine departments of molecular and human genetics and pediatrics and the Baylor Human Genome Sequencing Center and the University of Texas Health Science Center at Houston.

20 Oct 2014

CUMC researchers use innovative algorithm to find driving force behind aggressive form of glioblastoma

Using an innovative algorithm that analyzes gene regulatory and signaling networks, Columbia University Medical Center researchers have found that loss of a gene called KLHL9 is the driving force behind the most aggressive form of glioblastoma, the most common form of brain cancer.

10 Oct 2014

Case Western Reserve researcher lands Director's New Innovator Awards from NIH

For the second consecutive year, a Case Western Reserve University School of Medicine researcher has landed one of the year's much-coveted Director's New Innovator Awards from the National Institutes of Health. Principal investigator Rong Xu, PhD, assistant professor of medical informatics, will receive $2,377,000 for five years, starting immediately, to initiate computational analysis of thousands of drugs and their effects.

8 Oct 2014

Gaucher disease: an interview with Dr Clement Olivier, Shire

Gaucher disease is the most common condition within a family of rare diseases known as the lysosomal storage diseases. The disease causes lipids to accumulate in cells, which is why it is referred to as a storage disorder. The accumulation occurs mainly in the spleen, liver, and bones, but may also occur in the lungs, heart, and central nervous system.

30 Sep 2014

Early exposure to marijuana can lead to immune-related diseases in adulthood

When it comes to using marijuana, new research, involving mice and published in the October 2014 issue of the Journal of Leukocyte Biology, suggests that just because you can do it, doesn't mean that you should. That's because a team of Italian scientists have found that using marijuana in adolescence may do serious long-term damage to the immune system.

30 Sep 2014