Photodynamic Therapy News and Research

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Light-activated metal compound cuts off cancer cell's 'power source'

A space-age metal that formed part of the asteroid that destroyed the dinosaurs could provide a new method of treating cancer tumors selectively using light.

23 Sep 2019

Nanoparticles activated by X rays used to target deep tumours

A team of researchers from University of Texas at Arlington, University of Rhode Island and Brown University have collaborated to come up with use of nanoparticles in targeted therapy for deep seated cancers. Their success with the nanoparticples was published in a study titled, “X-ray induced photodynamic therapy with copper-cysteamine nanoparticles in mice tumors,” was published in the latest issue of the journal Proceedings of the National Academy of Sciences.

8 Sep 2019

Sick mitochondria pollute the cells, cause telomere damage

Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they're supposed to be supplying with power.

27 Aug 2019

Roswell Park receives more than $15 million in grants for cancer research

Roswell Park Comprehensive Cancer Center researchers have received more than a dozen recent grant awards totaling more than $15.4 million.

14 Aug 2019

New chemoimmunotherapy regimen for aggressive form of lymphoma gets FDA approval

A cancer therapy based on the work of Ben Seon, PhD, at Roswell Park Comprehensive Cancer Center has been approved by the U.S. Food and Drug Administration for patients with an aggressive form of non-Hodgkin lymphoma.

24 Jun 2019

Researchers propose a new look at the role of ferroptosis in cancer development

Professor of Ghent University and Lead Researcher at the Institute of Biology and Biomedicine of the Lobachevsky University Dmitri Krysko together with scientists from Germany, Professor Marcus Conrad and Professor Jose Pedro Friedmann Angeli recently published an article in the journal Nature Reviews Cancer, one of the highest-rated journals that occupies the 2nd line in the oncology section among 223 journals in this category and has an impact factor of 42.78 according to WoS data.

7 Jun 2019

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers have discovered a new genetic variant responsible for blood vessel dysregulation in the development of age-related macular degeneration (AMD).

29 May 2019

NETRF announces $2.5 million funding for neuroendocrine cancer research

The Neuroendocrine Tumor Research Foundation continues its aggressive funding of neuroendocrine cancer research with eight new grants totaling $2.5 million.

7 Feb 2019

Iridium attached to albumin can attack cancer cells when blasted with light

A new compound based on Iridium, a rare metal which landed in the Gulf of Mexico 66 M years ago, hooked onto albumin, a protein in blood, can attack the nucleus of cancerous cells when switched on by light, University of Warwick researchers have found.

4 Feb 2019

Innovative ‘light’ method demonstrates positive results in fight against malignant tumors

A team of scientists from the National University of Science and Technology "MISIS", the Moscow Technological University and the Pirogov Russian National Research Medical University has experimentally proved the effectiveness of the formerly suggested "light" method in oncotherapy.

18 Jan 2019

UC researcher focuses on light-mediated therapies to target breast cancer

When treatment is working for a patient who is fighting cancer, the light at the end of the tunnel is easier to see.

17 Oct 2018

Rapid inactivation of MRSA superbugs using a simple LED array

Purdue University researchers are testing whether a light-active version of heme, the molecule responsible for transporting oxygen in blood circulation, may help people infected with MRSA.

12 Oct 2018

Researchers develop near-infrared fluorophores-based PDT to cure cancer with less side effects

A KAIST research team developed near-infrared fluorophores-based photodynamic therapy that reduced the downside of existing PDTs.

16 Jul 2018

Photoswitchable drugs may light the way to treat disease with fewer side effects

Side effects from drugs working in non-target locations within the body can cause debilitating symptoms, often resulting in patients stopping their course of treatment early.

4 Apr 2018

Scientists develop water-soluble warped nanographene for bioimaging

An international team of scientists has developed a water-soluble "warped nanographene", a flexible molecule that is biocompatible and shows promise for fluorescent cell imaging.

19 Feb 2018

Japanese scientists synthesize water-soluble warped nanographene

Graphene and its nano-sized little sibling, nanographene, are well known for their remarkable photoelectronic properties. However, biomedical applications are hampered by the insolubility of the materials, especially in water.

12 Feb 2018

NUS scientists develop new way to wirelessly deliver light for cancer treatment

A team of scientists from the National University of Singapore has developed a way to wirelessly deliver light into deep regions of the body to activate light-sensitive drugs for photodynamic therapy.

30 Jan 2018

Combination of anti-malarial drug and photosensitizer could effectively kill cancer cells

Artemisinin, a potent anti-malarial drug, has been widely hailed as a promising alternative cancer treatment. Scientists from the National University of Singapore recently showed that its anti-cancer properties could be enhanced by 10 folds when used in combination with Aminolaevulinic acid, a photosensitizer or a drug which, upon exposure to light, leads to generation of free radicals that can kill cells.

18 Sep 2017

Motorized molecules driven by light to cut into cancer cells

Researchers have developed a novel technique where molecules would be motorized using light and these would be used to drill holes in the membranes of individual cells such as the cancer cells. This could bring the treatment molecule into the cancer cell directly and cause them to die.

31 Aug 2017

Researchers identify cytotoxic nature of two-dimensional black phosphorous

When environmental and soil chemist Baoshan Xing at the University of Massachusetts Amherst began reading in 2014 that a new, two-dimensional material known as layered black phosphorous (BP) was gaining the attention of biomedical researchers for use in drug delivery systems and tumor photothermal therapy, he was both intrigued and concerned.

31 Aug 2017