Plague News and Research

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Avidocin protein could prevent or treat E. coli O157:H7-induced diarrhea

A novel antibacterial protein targeted against E. coli O157:H7 may offer a way to prevent or treat serious food-borne bacterial infections, as demonstrated in a study published in the December issue of Antimicrobial Agents and Chemotherapy.

21 Nov 2011

Insights into potential causes of temporomandibular joint disorders

New findings about painful jaw problems that plague millions of Americans are leading to a better understanding of pain disorders.

11 Nov 2011

CLASS Act provision of health care reform depicts a practical but disappointing reality

The Obama Administration's recent decision not to implement the Community Living Assistance and Services Act provision of health care reform represents a practical but disappointing reality - voluntary enrollment in health and long-term care insurance programs is anything but a sure bet among Americans.

5 Nov 2011

Report showcases high burden of NTDs in India, South Asia

The open-access journal PLoS Neglected Tropical Diseases on Tuesday "published a comprehensive report showcasing the disproportionately high burden of neglected tropical diseases (NTDs) in India and South Asia," the Global Network for Neglected Tropical Disease's "End the Neglect" blog reports.

27 Oct 2011

DNA synbodies, a new class of affinity reagents, gets major NIH boost

An ongoing Arizona State University effort to develop a revolutionary class of reagents that holds great promise for the future of medicine has received a major boost with a three-year, $4 million award from the National Institutes of Health.

24 Oct 2011

Four companies receive NIAID contracts to develop broad-spectrum therapeutics

Four companies are to develop broad-spectrum therapeutics-antibiotics, antivirals and an antitoxin-to prevent or treat diseases caused by multiple types of bacteria or viruses, under contracts awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

14 Oct 2011

Genetic mystery of bacterium causing ‘Black Death’ revealed

Between 1347 and 1351 - a period of just five years, Europe's Black Death wiped out about 30 million people - 30 to 50% of the population on the continent. Now geneticists have reconstructed the genome of the bacterium that caused the plague. It is found to be an ancient strain of a bacterium called Yersinia pestis very similar to the strain the exists today.

13 Oct 2011

GlobalPost examines how Indian city of Surat cleaned up after 1994 plague outbreak

GlobalPost reports how, spurred by an outbreak of the pneumonic plague in 1994, the Indian city of Surat "successfully went from one of the country's dirtiest cities to one of its cleanest in 18 short months." The news service writes that "after 54 residents died and some 300,000 fled to escape a possible quarantine, the people who stuck around were willing to get with the program -- working to eliminate the tons of garbage and overflowing sewers that had inundated the city with disease-carrying rats."

30 Sep 2011

Anthrax defenses need to be strengthened: Experts

It has been a decade since the anthrax attacks brought home the reality of bioterrorism and the nation now has a stockpile of some basic tools to fight back against a few of the threats that worry defense experts the most.

28 Sep 2011

Study identifies genetic mutations that affect immune response to measles vaccination

Researchers at Mayo Clinic are hacking the genetic code that controls the human response to disease vaccination, and they are using this new cipher to answer many of the deep-seated questions that plague vaccinology, including why patients respond so differently to identical vaccines and how to minimize the side effects to vaccination.

23 Sep 2011

U of C researchers create new model of obsessive-compulsive disorder

A new model of obsessive-compulsive disorder (OCD) that mirrors both symptoms of the disease and the timing of its treatment in humans has been created by University of Chicago researchers, according to a new study.

16 Sep 2011

Medical students may act on unconscious racial preferences

New Johns Hopkins research shows that medical students — just like the general American population — may have unconscious if not overt preferences for white people, but this innate bias does not appear to translate into different or lesser health care of other races.

8 Sep 2011

BARDA awards GlaxoSmithKline contract for development of dual-purpose broad spectrum antibiotic

The federal government today issued a contract for advanced research and development of a dual-purpose broad spectrum antibiotic with potential to treat illnesses caused by bioterrorism threats such as plague and tularemia, as well as more certain life-threatening infections, known as Gram-negative infections, associated with prolonged hospitalization.

7 Sep 2011

Scientists using molecular epidemiology to diagnose and track disease outbreaks

The New York Times examines "new methods of quickly sequencing entire microbial genomes that are revolutionizing the field" of molecularly epidemiology and could help public health officials identify and track disease outbreaks.

31 Aug 2011

Study may help explain plague's rapid evolution and aid in development of therapeutics

In the evolutionary blink of an eye, a bacterium that causes mild stomach irritation evolved into a deadly assassin responsible for the most devastating pandemics in human history. How did the mild-mannered Yersinia pseudotuberculosis become Yersinia pestis, more commonly known as the Plague?

30 Aug 2011

Genetic analysis of medieval plague skeletons proves the presence of y. pestis bacteria

Genetic analysis of medieval plague skeletons proves the presence of yersinia pestis bacteria. Collaboration between the University of Tübingen and Canadian scientists proves today's plague pathogen has been around at least 600 years.

30 Aug 2011

Black Death bacteria may be extinct - Study

The bacteria that caused the Black Death or plague, which wiped out millions in mid-14th century Europe, may be extinct, according to a new study. The Black Death claimed the lives of one-third of Europeans in just five years from 1348 to 1353. Until recently, it was not certain whether the bacterium Yersinia pestis - known to cause the plague today - was responsible for that most deadly outbreak of disease ever. Now, the University of Tübingen's Institute of Scientific Archaeology and McMaster University in Canada have been able to confirm that Yersinia pestis was behind the great plague.

30 Aug 2011