Plasmodium falciparum News and Research

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Vaccine against malaria could be ready in 5 years

Malaria kills more than one million people every year so the news that an effective vaccine could be available within five years is more than welcome.

9 Dec 2008

Genomics and bioinformatics could be the future in battle against malaria

Malaria, one of the oldest diseases known to man, has shown no signs of slowing down as it ages.

26 Nov 2008

Indian physicians concerned about malaria drug resistance, recommend combination therapy

India has reported an increase in drug-resistant malaria cases this year, leading physicians to express concern and recommend that the disease be treated with a combination of drugs, India's Daily News and Analysis reports.

26 Aug 2008

International goals to reduce malaria burdens not likely to be achieved

For malaria control goals to be achieved, we must in the future tie funding commitments closer to level of need, says new research by Bob Snow and colleagues from the Kenyan Medical Research Institute-Oxford University-Wellcome Trust Collaborative Programme.

22 Jul 2008

Scientists reveal potential new target for anti-malarial drugs

Scientists funded by the Wellcome Trust have identified a key mechanism that enables malaria-infected red blood cells to stick to the walls of blood vessels and avoid being destroyed by the body's immune system. The research, published today in the journal Cell, highlights an important potential new target for anti-malarial drugs.

10 Jul 2008

New understanding of how malaria parasite survives in and totally changes red blood cells

A new study-done on a scale an order of magnitude greater than anything previously attempted in the field of malaria-has uncovered an arsenal of proteins produced by the malaria parasite that allows it to hijack and remodel human red blood cells, leaving the oxygen-carrying cells stiff and sticky.

8 Jul 2008

'Benign' malaria found to just as deadly

Australian scientists have found that a strain of malaria previously considered to be 'benign' is actually potentially fatal.

17 Jun 2008

Scientists demonstrate feasibility of preventing malaria parasite from becoming sexually mature

Researchers have demonstrated the possibility of preventing the human malaria parasite, Plasmodium falciparum, which is responsible for more than a million malaria deaths a year, from becoming sexually mature.

5 Jun 2008

FSU research may speed new malaria treatments, vaccines for children

April 25 is World Malaria Day 2008 and despite the grim statistics out of Africa there's cause for celebration. Florida State University biologists have discovered an autoimmune-like response in blood drawn from malaria-infected African children that helps to explain why existing DNA-based anti-malaria vaccines have repeatedly failed to protect them.

23 Apr 2008

New inexpensive test for malaria detection

ETH Zurich professor Peter Seeberger has been working on a sugar-based malaria vaccine for years.

4 Mar 2008

Could a simple vitamin A and zinc supplement help protect young children from malaria?

A randomized double blind trial reported in the open access publication, Nutrition Journal, would suggest the answer is yes.

7 Feb 2008

New genetic findings on malaria parasite

The malaria parasite has been studied for decades, but surprisingly, little is known about how it behaves in humans to cause disease.

29 Nov 2007

Whole parasite malaria vaccine to be manufactured for clinical trials

Sanaria Inc. and the PATH Malaria Vaccine Initiative has officially opened a one-of-a-kind clinical manufacturing facility to produce a vaccine that uses a weakened form of the malaria parasite to fight a disease that annually kills more than one million people, most of them African children.

29 Oct 2007

Malaria remains formidable challenge in the Americas

Malaria remains a formidable challenge for the countries of the Americas and more action is needed to improve national control programs to reduce the burden of the disease, health ministers from the Americas heard today.

8 Oct 2007

New understanding of the malarial parasite

About 2 million people die of malaria every year, of which more than a million are children in sub-Saharan Africa.

17 Sep 2007

Sugar key to malaria parasite invasion

Researchers at the Johns Hopkins Malaria Research Institute (JHMRI) have identified a sugar in mosquitoes that allows the malaria-causing parasite, Plasmodium falciparum, to attach itself to the mosquito's gut.

11 Sep 2007

Researchers look at malaria resistance to chloroquine

Funded by a $1.5 million grant from the National Institutes of Health (NIH), scientists at Binghamton University, State University of New York, hope to understand how the malaria parasite Plasmodium falciparum evolved resistance to the once-effective medication chloroquine.

3 Sep 2007

Start of Phase II trial of intravenous artesunate for children with severe malaria

A multicentre Phase II trial of intravenous artesunate will begin recruitment of patients in September.

30 Aug 2007

Binghamton University researchers investigate evolving malaria resistance

Funded by a $1.5 million grant from the National Institutes of Health, scientists at Binghamton University, State University of New York, hope to understand how the malaria parasite Plasmodium falciparum evolved resistance to the once-effective medication chloroquine.

30 Aug 2007