Plavix News and Research

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Data expands the clinical utility of deCODE tests for heart attack, atrial fibrillation and stroke

Several presentations by deCODE genetics scientists and independent researchers at the American Heart Association Scientific Sessions 2008 being held at the New Orleans Convention Center from November 8 to12 are expected to expand upon the clinical utility of evaluating individual risk of heart attack, or atrial fibrillation and stroke, respectively, by measuring the genetic markers that are the basis of the deCODE MI and deCODE AF tests.

11 Nov 2008

Experts available to comment on risk of sudden cardiac death in 30 days following a heart attack

A new study in the November 5th 2008 issue of JAMA finds that during the first month after a heart attack, patients may have an increased risk for sudden cardiac death.

5 Nov 2008

Factor Xa inhibitor Apixaban and antiplatelet therapy after acute coronary syndrome

Data from a phase II study of an investigational drug designed to block formation of blood clots show potential for added protection against a second heart attack or stroke among patients who are already taking state-of-the-art prevention therapy.

2 Sep 2008

Scientists discover platelets play an important early role in promoting cerebral malaria

Platelets - those tiny, unassuming cells that cause blood to clot and scabs to form when you cut yourself - play an important early role in promoting cerebral malaria, an often lethal complication that occurs mostly in children.

18 Aug 2008

Rheumatoid arthritis doubles a person's risk of heart attack

People coping with rheumatoid arthritis or lupus already have a lot to deal with. Even so, paying attention to heart health may be especially important for this group.

29 Jul 2008

Reducing blockage fails to improve access to the bloodstream for kidney dialysis

Reducing early blockages in bloodstream access for kidney failure treatment does not increase the likelihood that the access will function adequately for long-term treatments, according to a study funded by the National Institutes of Health. Results were published May 14, 2008, in the Journal of the American Medical Association.

22 May 2008

Former Bristol-Myers Squibb exec indicted for lying about Plavix blood-thinning drug

The Department of Justice announced today that the former senior vice president of Bristol-Myers Squibb Company (BMS), Andrew Bodnar, was indicted for his role in lying to the federal government about a patent deal involving the popular blood-thinning drug, Plavix, used by heart attack, stroke and other patients.

23 Apr 2008

Fugitive cancer cells can be blocked by stopping blood cells that aid them

Cancer cells get a helping hand from platelets, specialized blood cells involved in clotting.

10 Mar 2008

Half of patients undergoing cerebrovascular stent placement do not respond well to clopidogrel

A study by researchers at Rush University Medical Center, published in the February issue of the American Journal of Neuroradiology, finds that half of patients undergoing cerebrovascular stent placement did not respond well to clopidogrel.

7 Feb 2008

Daiichi Sankyo, Lilly submit NDA for investigational antiplatelet drug, Prasugrelin U.S.

Daiichi Sankyo Company, Limited and Eli Lilly and Company have announced that on Wednesday, Dec. 26, 2007, they submitted a New Drug Application (NDA) for prasugrel to the U.S. Food and Drug Administration (FDA).

7 Jan 2008

Big question over new blood-clot buster drug Prasugrel

New research has revealed that the drug Prasugrel produced by drug company Eli Lilly increases the risk of serious bleeding when compared to the standard therapy.

5 Nov 2007

Top five prescribed drugs

With a total nearly $5 billion, Lipitor, a cholesterol-reducing drug, ranked first in terms of total spending on prescription medicines by adults ages 18 to 64 in 2004, and another cholesterol-fighting drug, Zocor, ranked fourth at $2.3 billion, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

21 Sep 2007

U.S. DOJ investigation of Bristol-Myers Squibb in Plavix patent settlement resolved

Bristol-Myers Squibb has pleaded guilty to two counts of violating 18 U.S.C. Sec. 1001 in U.S. District Court for the District of Columbia. This guilty plea resolved as to the company the previously disclosed investigation by the Antitrust Division of the U.S. Department of Justice into the proposed settlement of the Plavix patent litigation with Apotex Inc., and Apotex Corp. (Apotex).

16 Jun 2007

Bare metal stents provide a safer choice

While drug-eluting stents are effective in keeping open diseased heart arteries, they should not be used for patients who need to have non-cardiac surgery a short time after an interventional heart procedure.

15 May 2007

Thailand wins round two in battle to access cheaper AIDS drugs

The military government in Thailand has won the second round in it's battle to access cheaper AIDS drugs for the nations 580,000 AIDS sufferers.

23 Apr 2007

Micell Technologies presents data on novel drug-eluting stents

Micell Technologies has announced that the Company will be presenting data on use of its supercritical fluid (SCF) surface modification technology for drug-eluting stents at the upcoming Society for Biomaterials 2007 Annual Meeting, April 19-21 2007 in Chicago, Illinois.

19 Apr 2007

Long-term safety of drug-eluting stents in off-label use

Research presented at the American College of Cardiology's Innovation in Intervention: i2 Summit 2007 in New Orleans, La, paints a picture of the "real world" use of drug-eluting stents and offers new insight into the connection between blood clotting, or thrombosis, in the stent - a dangerous complication - and adherence and responsiveness to anti-clotting medication.

3 Apr 2007

Plavix appears to be safe during and after heart bypass

Heart surgeons don't have to choose between taking a coronary-bypass patient off the popular anti-clotting drug clopidogrel (Plavix) after off-pump heart bypass surgery or having the patient bleed excessively in the days following surgery, according to a new study by researchers at Jefferson Medical College.

28 Mar 2007

Thailand holds drug giants over a barrel

The government of Thailand, has already upset some of the big drug companies by overriding patent licenses for generic versions of heart and HIV/AIDS pills, and is now planning to go one step further unless drug giants cut their prices.

13 Feb 2007

Thailand the latest drug patent buster

Thailand's military government has used World Trade Organization (WTO) rules regarding intellectual property, to allow the sale of generic versions of two important drugs used to treat HIV/AIDS and heart disease.

29 Jan 2007