Plavix News and Research

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FDA advisory panel on drug-eluting stents to include physicians with industry ties

FDA will waive rules that prohibit advisory panel members from having financial ties to companies whose products are being reviewed to allow six physicians with ties to Johnson & Johnson and other heart device manufacturers to serve on a panel examining the possible health risks of drug-eluting stents, Bloomberg/South Florida Sun-Sentinel reports.

5 Dec 2006

Drug coated heart stents more likely to cause blood clots

A review and analysis of studies on drug-coated heart devices known as stents, has found that patients with them are four to five times more likely to get blood clots when compared to the older bare-metal variety.

4 Dec 2006

Researchers create roadmap to integrin activation

Calling it an important technical advance in the study of the complex receptors and pathways of the body's cellular system, researchers at the University of California, San Diego (UCSD) School of Medicine have reconstructed the signaling pathways that impact activation of a receptor that is critical to the control of bleeding and to the thrombosis that occurs in heart attacks and strokes.

18 Sep 2006

More physicians now visit web sites to find information on brand-name prescription drugs

An increased number of physicians visited Web sites that promote brand-name prescription drugs during the first six months of 2006 to seek information about dosages and side effects, according to a recent Manhattan Research study, the Newark Star-Ledger reports.

18 Sep 2006

How effective is continued Plavix therapy in patients undergoing a repeat stent procedure?

Clopidogrel (Plavix) is used worldwide in millions of patients after placement of coronary artery stents. Sales of the drug exceed 5 billion US dollars.

5 Sep 2006

FDA approves Plavix for STEMI heart attacks

The Food and Drug Administration (FDA) today approved the use of Plavix (clopidogrel bisulfate) for patients who have had a type of heart attack called acute ST-segment elevation myocardial infarction (STEMI), who are not going to have coronary artery repair (angioplasty).

17 Aug 2006

Jefferson neurosurgeons use innovative "Wingspan Stent System" to open clogged brain arteries

Neurosurgeons at Thomas Jefferson University Hospital in Philadelphia are the first in the region and among the first in the nation to successfully use a new stent specifically designed to open potentially life-threatening clogged arteries in the brain, preventing a stroke.

22 Mar 2006

Sanofi-aventis and Bristol-Myers Squibb agree to settle patent dispute with Apotex

Sanofi-aventis and Bristol-Myers Squibb have announced that they have reached an agreement subject to certain conditions with Apotex to settle the patent infringement lawsuit pending between the parties in the U.S. District Court for the Southern District of New York.

21 Mar 2006

New device for fixing holes in hearts of young stroke patients

As many as one in four adults is walking around with a "hole" between the upper chambers of the heart. Most of them will never know it.

14 Mar 2006

Aspirin still the best for reducing the heart attack risk

New research has revealed that the addition of the blood-thinning drug Plavix to a daily dose of aspirin does not lower the risk of death, heart attack or stroke in high-risk patients.

13 Mar 2006

Use of a common type of antidepressant may increase gastrointestinal (GI) bleeding

In fact, the study suggests that the increase is similar to that associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs, known as pain relievers). DDW is the largest international gathering of physicians, academics and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

17 May 2005

Monitoring program has successfully identified a large number of previously unknown, serious and often-fatal drug reactions

A monitoring program developed by a Northwestern University researcher has successfully identified a large number of previously unknown, serious and often-fatal drug reactions associated with 15 commonly used drugs, including Plavix®, thalidomide and drug-coated cardiac stents.

3 May 2005

New drug combo helps prevent strokes

A British research team at St. George's Hospital Medical School in London, have found that the addition of the anti-clotting drug Plavix to daily doses of aspirin helps prevent the risk of later strokes better than using aspirin alone.

25 Apr 2005

Blood clotting combo saves heart patients lives

Two studies presented Wednesday at the American College of Cardiology's annual scientific sessions in Orlando, Fla. have found that the clot-preventing drug Plavix when added to the treatment of people with severe heart attacks helps reopen their clogged arteries and saves lives.

9 Mar 2005

Studies find Aspirin resistance in up to 27% of Aspirin users

While aspirin remains a crucial and cost-effective therapy for the prevention and management of cardiovascular diseases, research suggests that a significant percentage of the 25 million Americans on a chronic aspirin regimen are "aspirin resistant," or do not achieve sufficient antiplatelet effects from aspirin.

7 Mar 2005

St. John's wort increases effectiveness of Plavix

The widely used herbal remedy St. John's wort appears to amplify the action of the popular blood-thinning drug clopidogrel, sold as Plavix, a small new clinical study finds.

6 Mar 2005

Heart patients with gastrointestinal complications should use low doses of aspirin combined with drugs that treat stomach ulcers

Physicians are challenged in treating heart patients who may be at high-risk for gastrointestinal bleeding from aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs). Factors that place patients at high-risk include a history of ulcers or gastrointestinal complications such as bleeding, increased age and congestive heart failure.

20 Jan 2005

Clopidogrel (Plavix®) responses appear normal in largest data set

Although individual patients respond differently to treatment with the anti-platelet medication clopidogrel (brand name Plavix®), those variations appear normal and may not indicate important differences in the effectiveness of treatment, according to a new study (PDF file) in the Jan. 18, 2005 issue of the Journal of the American College of Cardiology.

19 Jan 2005

Angioplasty may replace bypass for more patients who are also receiving a new heart valve

The death rate during combination surgery to bypass clogged coronary arteries and simultaneously replace a heart valve in very sick patients can be as high as one in five, but a review of records of very sick patients who underwent balloon angioplasty, followed by heart valve replacement surgery, found only one death among 26 patients.

4 Jan 2005

U.S. drug prices rise by 3.4 percent during the first quarter of 2004, elderly especially hard hit

A new study released by AARP finds manufacturers' wholesale prices for the 197 brand name prescription drugs most frequently used by older Americans continued an upward climb.

1 Jul 2004