Polio News and Research

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Poliomyelitis (polio) is a highly infectious disease caused by a virus that invades the nervous system and can cause severe paralysis. The virus enters the body through the mouth and multiplies in the intestine. Initial symptoms are fever, fatigue, headache, vomiting, stiffness in the neck, and pain in the limbs. One in 200 infections leads to irreversible paralysis (usually in the legs). Among those paralyzed, 5-10% die when their breathing muscles become immobilized. Polio mainly affects children under five years of age. Naturally occurring polio was eliminated in the U.S. in 1979 and in the Western Hemisphere by 1991; however, worldwide efforts are continuing towards eradication of this contagious and devastating disease.

5-in-1 combo vaccine increases on-time immunization in children

A "5-in-1" combination vaccine increases the percentage of children receiving all recommended vaccinations at the scheduled time, reports a study in the February issue of The Pediatric Infectious Disease Journal.

11 Feb 2009

Researchers solve failed vaccine mystery

Research led by Johns Hopkins Children's Center scientists has figured out why a respiratory syncytial virus vaccine used in 1966 to inoculate children against the infection instead caused severe respiratory disease and effectively stopped efforts to make a better one.

15 Dec 2008

Mathematical models of adaptive immunity

More than five million people die every year from infectious diseases, despite the availability of numerous antibiotics and vaccines. The discovery of penicillin to treat bacterial infections, along with the development of vaccines for previously incurable virus diseases such as polio and smallpox, achieved great reductions in mortality during the mid-20th century.

11 Dec 2008

Why are so many infectious diseases jumping from animals to humans?

Why do we have so little capacity to predict epidemics, or avoid them? Some answers, and possible solutions, can be found in the first trench-to-bench guide to wild primate infectious diseases, published Nov. 17 in the Yearbook of Physical Anthropology.

18 Nov 2008

Previously unknown regulatory step during HIV replication provides potential new target for HIV/AIDS therapy

A previously unknown regulatory step during human immunodeficiency (HIV) replication provides a potentially valuable new target for HIV/AIDS therapy, report researchers at the Salk Institute for Biological Studies and the University of Wisconsin, Madison.

16 Nov 2008

Polio could be wiped out in Nigeria thanks to improved vaccine

A recently introduced polio vaccine is four times more effective at protecting children than previous vaccines and has the potential to eradicate type 1 polio in Nigeria if it reaches enough children, according to a study published today in the New England Journal of Medicine.

19 Oct 2008

Most vaccine-allergic children can still be safely vaccinated

With close monitoring and a few standard precautions, nearly all children with known or suspected vaccine allergies can be safely immunized, according to a team of vaccine safety experts led by the Johns Hopkins Children's Center. Writing in the September issue of Pediatrics, the multicenter research team offers pediatricians a step-by-step tool for quickly identifying children with allergic reactions to vaccines, and a much-needed guide, they say, to safely immunize those who are allergic.

2 Sep 2008

Shots are nothing to shy away from with the right approach

"Getting shots may seem burdensome and even downright scary to some children, but they protect children against dangerous and deadly diseases."

28 Aug 2008

U.S. tightens visas with vaccine requirements

New vaccine requirements will affect anyone who is applying for an immigrant visa for entry into the U.S. and anyone seeking adjustment of status for permanent residence.

23 Jul 2008

Sanofi Pasteur inaugurates high-tech vaccine production facility in France

Sanofi Pasteur, the vaccines division of sanofi-aventis Group, announced today the inauguration of a high-tech vaccine production facility in France to respond to soaring demand worldwide.

25 Jun 2008

FDA approves Kinrix - combination vaccine for diphtheria, tetanus, pertussis and polio diseases in one shot

GlaxoSmithKline has announced that the U.S. Food and Drug Administration (FDA) has approved Kinrix [Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine], the first combination vaccine to offer protection against diphtheria, tetanus, pertussis and polio diseases in one shot.

24 Jun 2008

Public health agencies call on G8 leaders to allocate increased resources to health programs worldwide

The heads of several organizations involved in public health issues worldwide on Tuesday called on the Group of Eight industrialized nations to invest more resources in health and disease programs, the AP/USA Today reports.

11 Jun 2008

US$28 million needed for Myanmar says WHO

WHO and its Health Cluster partners in Myanmar have launched a six-month and US$ 28 million action plan to provide immediate health care for cyclone survivors and to support longer-term efforts to rebuild the country's ravaged health system.

30 May 2008

New treatments for viral and other diseases by blocking genes

The elusive goal of developing effective treatments for viral diseases such as AIDS and influenza has been brought closer by dramatic progress in the ability to interfere with viral genetic machinery. The stage was set for a coordinated European effort to accelerate research and stimulate development of new treatments against viral diseases at a recent research conference organised by the European Science Foundation (ESF).

26 May 2008

Archbishop Tutu calls on governments to address health issues in Africa, including HIV/AIDS

South African Archbishop Desmond Tutu on Tuesday at the World Health Assembly in Geneva called on governments to increase their efforts to fight diseases -- including HIV/AIDS, tuberculosis and malaria -- in Africa, the Associated Press reports.

21 May 2008

Would you let your child participate in medical research?

Advances in medicine - new treatments, cures, vaccines and medicines - are driven by research involving humans. But when it comes to medical research that requires children to be involved, researchers often struggle to find participants.

13 May 2008

Death toll in China now at 39 as 5 more children die from enterovirus 71

The death toll in China from enterovirus 71 (EV71) has risen to 39 with the deaths of five more children; EV71 belongs to the same family as the polio virus and is a strain of hand, foot and mouth disease (HFMD).

13 May 2008

New data reveals impact of deadly human papillomavirus in Latin America, Caribbean

Thirty-three thousand women in Latin America and the Caribbean die each year of preventable cervical cancer, caused by a virus that infects 20 percent of men and women in the region and as many as 30 percent of the youngest women, according to a new study.

12 May 2008

1,884 cases of enterovirus 71 in China

As of April 29 a total of 1,884 cases including 20 deaths of hand, foot and mouth disease (HFMD) due to enterovirus (EV-71) have been reported among infants and young children. The 20 deaths are in Fuyang city in Anhui Province, China.

2 May 2008

Parents follow pediatrician advice on administering MMR vaccinations

News stories about an allegedly harmful link between the mumps, measles and rubella vaccine and the onset of autism had little effect on whether U.S. parents immunized their children, according to a review of immunization records and news stories.

7 Apr 2008