Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Exploring microstructural brain abnormalities after mild COVID-19

Researchers assessed the functional and microstructural brain abnormalities, tiredness, and cognitive impairment after mild coronavirus disease 2019 (COVID-19).

19 Dec 2022

Study suggests sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness following COVID-19 hospitalization

Researchers used a multi-modal approach to examine the types, prevalence, and relevance of sleep disturbance in individuals hospitalized with COVID-19 and determine associations between dyspnea and sleep disturbance.

19 Dec 2022

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Researchers investigated whether coronavirus disease 2019 (COVID-19)-associated chemosensory alterations were predictive of serological responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among United States (US) residents.

16 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Researchers used serological measurements from a longitudinal cohort to evaluate the use of binding antibodies against the SARS-CoV-2 spike protein receptor binding domain as correlates of protection against the immune evasive Omicron subvariants BA.1 and BA.2.

16 Dec 2022

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

Researchers investigated the efficacy of ritonavir and nirmatrelvir combination treatment in reducing the risk of COVID-19 severity outcomes such as hospital admissions and deaths when administered during the initial period of SARS-CoV-2 infections.

16 Dec 2022

The mpox viral load kinetics over time in various parts of the body

Researchers characterized the time to mpox virus clearance of immunocompetent individuals with mild MPX in a real-world community-based setting utilizing longitudinal information.

16 Dec 2022

Study reports that delaying surgery post-COVID-19 reduces the risk of postoperative cardiovascular issues

Researchers assessed the temporal relationship between COVID-19 diagnosis and surgery time with the risk of occurrence of cardiovascular morbidity events within 30 days of surgery.

16 Dec 2022

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Researchers described tree-based scan statistics for pediatric long COVID-19.

16 Dec 2022

New immunosensor could be a fast, inexpensive, and convenient tool to detect COVID-19

A new immunosensor based on Quenchbody technology shows great potential as a fast, inexpensive, and convenient tool to detect SARS-CoV-2.

15 Dec 2022

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

Researchers evaluated the emergence and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in Canada.

15 Dec 2022

How do predicted ecological niches of the mpox virus compare with that of 99 mammal species?

Researchers compared ecological niches to identify probable mpox virus reservoir hosts.

15 Dec 2022

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

Researchers estimated influenza VE in patients aged ≥6 months seeking outpatient care for ARI due to the influenza A(H3N2) virus between October 2021 and April 2022 in the United States (US).

15 Dec 2022

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

Researchers evaluated the change in symptoms and risk factors associated with positive SARS-CoV-2 tests during the COVID-19 pandemic and compared it to those associated with positive tests of other respiratory viruses among residents of King County, Washington, in the United States.

14 Dec 2022

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

Researchers isolated SARS-CoV-2 spike protein-targeted mAbs from convalescent healthcare workers, emphasizing the IGHV1-69 gene, the gene with the greatest structural and allelic variation.

14 Dec 2022

Characterization of immune evasion and cell entry for new variants: BQ.1.1, XBB.1, and BR.2.1

In a recent study posted to the medRxiv* preprint server, researchers in Australia and Switzerland evaluated the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in community-based settings of the United States (US).

13 Dec 2022

Polymerase Chain Reaction News and Research

Further Reading

Exploring microstructural brain abnormalities after mild COVID-19

Study suggests sleep disturbance is associated with dyspnoea, anxiety, and muscle weakness following COVID-19 hospitalization

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

The mpox viral load kinetics over time in various parts of the body

Study reports that delaying surgery post-COVID-19 reduces the risk of postoperative cardiovascular issues

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

New immunosensor could be a fast, inexpensive, and convenient tool to detect COVID-19

Exploring dynamics of emergence and spread of SARS-CoV-2 variants of concern

How do predicted ecological niches of the mpox virus compare with that of 99 mammal species?

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

Characterization of immune evasion and cell entry for new variants: BQ.1.1, XBB.1, and BR.2.1

Overview of current methods, technologies, and applications in the molecular diagnosis of mpox

Immunogenicity of SARS-CoV-2 antibody response in immune naïve children and adults

What is the incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir?

Reports of Mpox disease following recent vaccination

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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