Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Anti-SARS-CoV-2 titers predict COVID severity

A recent study published in the journal Viruses reported that antibody titers against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) could serve as a marker for the severity of coronavirus disease 2019 (COVID-19).

22 May 2022

Evaluating serum levels of S100A9 as an inflammatory marker of unfavorable outcomes in patients with COVID-19

Investigators demonstrated S100A9 as an inflammatory biomarker among hospitalized SARS-CoV-2 patients.

20 May 2022

Serologic response to SARS-CoV-2 may predict COVID-19 severity

A new study reported that antibody titers against SARS-CoV-2 could serve as a marker for the severity of COVID-19.

20 May 2022

Identification of long COVID patients through machine learning

Researchers developed a machine learning approach to identify patients with long coronavirus disease.

20 May 2022

Scientists explore mortality among women on hormone replacement therapy early in COVID-19 pandemic

A new study assessed the association of hormone replacement therapy or the use of the combined oral contraceptive pill with mortality among women with a previous history of COVID-19.

20 May 2022

Ensitrelvir demonstrates swift SARS-CoV-2 clearance and safety among individuals with asymptomatic, mild, or moderate SARS-CoV-2 infections

Researchers reported findings that assessed the safety and efficacy of Ensitrelvir among patients with asymptomatic or mild-to-moderate SARS-CoV-2 infection in Japan.

20 May 2022

Dogs trained to detect SARS-CoV-2 can sniff out infected passengers at airports

In a recent study published in the journal BMJ Global Health, researchers explored whether scent dogs can be trained to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals.

19 May 2022

SARS-CoV-2 Omicron linked to rise in croup in young children

A recent Pediatrics study assesses the causative relationship between SARS-CoV-2 infection and croup or “barking cough” in children.

19 May 2022

Downregulation of MHC-I surface expression by SARS-CoV-2 accessory proteins

Researchers analyze the mechanisms by which two SARS-CoV-2 accessory proteins, ORF3a and ORF7a, can downregulate the expression of MHC-I.

19 May 2022

sCPD9: a SARS-CoV-2 nasal vaccine candidate that may have superior efficacy

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19 May 2022

SARS-CoV-2 Omicron found to be more immune evasive than other variants among mild COVID-19 convalescent patients

Researchers evaluated the humoral and T lymphocyte immune responses against SARS-CoV-2 variants of concern among mild COVID-19 convalescent patients in South Australia.

19 May 2022

Study investigates the detection of antibodies against SARS-CoV-2 in urine

Researchers developed an enzyme-linked immunosorbent assay to detect antibodies against SARS-CoV-2 in urine samples.

19 May 2022

Incidence of arterial and venous thromboembolism and death in COVID-19 patients

Researchers estimated the incidence of arterial or venous thrombosis in patients with coronavirus disease 2019.

19 May 2022

Prevalence of long COVID-19 after Omicron infection

A recent article posted to the medRxiv* preprint server analyzed the long coronavirus disease (COVID) linked with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant.

18 May 2022

Study explores neurologic complications in pediatric COVID-19 cases

Researchers evaluated neurologic complications in pediatric cases of COVID-19.

18 May 2022

Case report: human breast milk from vaccinated woman clears persistent SARS-CoV-2 infection

A new study published in the journal Viruses aimed to report the effects of plasma infusion and then breastmilk ingestion as a therapy for persistent SARS-CoV-2 infection in a patient with a common variable immunodeficiency (CVID) phenotype.

18 May 2022

The efficacy of CoronaVac against SARS-CoV-2 in cancer patients

In a recent study published in the Journal of Medical Virology, researchers analyzed the efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in preventing SARS-CoV-2 infection among cancer patients.

18 May 2022

Camelid IFNs could play important role in combating emerging zoonotic pathogens

In a recent study published in the Developmental & Comparative Immunology journal, the discovery of a novel form of mammalian interferon-Beta (IFN-β) with four cysteine residues from the dromedary camel and the five remaining members of the mammalian suborder Tylopoda is described.

17 May 2022

Scientists explore triggers associated with transplacental transmission of SARS-CoV-2

A new study examines the risk of fetal SARS-CoV-2 infection following infection of a pregnant mother with the virus.

17 May 2022

Mice live longer with nasal gene therapy

In a recent study published in the Proceedings of the National Academy of Sciences journal, researchers assessed the efficiency of a novel intranasal and injectable therapy in improving life expectancy.

17 May 2022