Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Using PCR-based genotyping to detect SARS-CoV-2 delta-omicron coinfection

In a recently published ‘Letter to the Editor’ in the journal Microbiology Spectrum, scientists have described the procedure of polymerase chain reaction (PCR)-based genotyping in identifying delta-omicron coinfection in clinical samples.

9 May 2022

Prenatal exposure to SARS-CoV-2 raises risk of neurological disorders in infants

In a recent study published in the journal PLOS One, researchers investigated the early indicators of neurological dysfunctions, including the absence of fidgety movements, in three to five-month-old infants prenatally exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 May 2022

Outcomes of COVID-19 treatment with Paxlovid

Researchers investigated the outcomes of COVID-19 treatment with paxlovid.

5 May 2022

Results indicate that Omicron infection induces low levels of neutralizing antibodies in immunocompetent individuals

Researchers assessed the induction of variant-specific neutralizing antibodies against the SARS-CoV-2 spike and nucleocapsid proteins of several SARS-CoV-2 strains.

5 May 2022

Study assesses the efficacy and safety of lithium treatment in patients infected with severe SARS-CoV-2

Researchers assessed the efficacy and safety of using lithium for coronavirus disease 2019 (COVID-19) treatment.

5 May 2022

Study identifies two new Omicron lineages associated with a resurgence in infections in South Africa

Researchers assessed the emergence and evolution of SARS-CoV-2 Omicron variant in South Africa.

5 May 2022

Potential indirect and direct effects of SARS-CoV-2 on pancreatic islets in patients who became hyperglycemic after COVID-19

In a recent study published in Diabetes, researchers assessed the direct and indirect effects of SARS-CoV-2 on human pancreatic islets.

5 May 2022

Free SARS-CoV-2 spike protein fragments may trigger platelet activation and clot formation in COVID-19

In a recent study under review in the Nature Portfolio journal and currently available on the Research Square* preprint server, researchers investigated the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (SP) in the thrombi (or blood clots).

5 May 2022

Oral Nirmatrelvir's effects on long COVID symptoms

In a recent study posted to the Research Square* preprint server, researchers at the University of California, San Francisco, examined the cases of three individuals who received nirmatrelvir/ritonavir antiviral therapy at different stages following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

4 May 2022

Exploring definitions related to COVID-19 infection and deaths

Researchers assessed the definitions and reports of coronavirus disease 2019 (COVID-19)-related deaths.

4 May 2022

Evaluating immune protection after third and fourth doses of homologous and heterologous SARS-CoV-2 vaccines among kidney transplant recipients

Researchers evaluated the immune responses after the third and fourth doses of homologous and heterologous mRNA vaccines against COVID-19 in kidney transplant recipients.

4 May 2022

Study suggests SARS-CoV-2 Omicron is as deadly as past variants

A recent article under review at the Nature Portfolio journal and currently posted to the Research Square* preprint server compared the severity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant with prior mutants.

4 May 2022

Pets living in households with COVID-19 are high likely to seroconvert and become ill

In a recent study published in the journal Emerging Infectious Diseases, researchers investigated whether pet dogs and cats in the households of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected humans were at risk of infection.

3 May 2022

How a COVID support team mitigated SARS-CoV-2 transmission within a university community

Researchers demonstrated how a campus coronavirus disease support team [CCST] efficiently mitigated potential COVID 2019 (COVID-19) outbreaks within the school of public health (SPH) of the mid-Atlantic university in the United States (US).

3 May 2022

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

A recent study under review at Nature Portfolio and posted to the Research Square* preprint server depicted how cellular nucleic acid-binding protein (CNBP) inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

3 May 2022

Study explores which occupations had the greatest risk of SARS-CoV-2 infection and how relative differences varied over the pandemic

Researchers investigated occupations at the highest risk for SARS-CoV-2 infection.

3 May 2022

Effectiveness of ChAdOx1-S COVID-19 booster vaccine

Researchers assessed the effectiveness of ChAdOx1-S COVID-19 booster vaccination.

3 May 2022

Prior SARS-CoV-2 infection provides substantial and sustained protection from Omicron hospitalization

A population-level study conducted on residents of the Quebec province, Canada, has demonstrated that prior infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces robust and long-lasting protection against omicron re-infection and hospitalization. The level of protection further increases with coronavirus disease 2019 (COVID-19) vaccination.

3 May 2022

Novel wearable sensor can detect two key biomarkers of infection in sweat

University of Texas at Dallas bioengineers in collaboration with EnLiSense LLC have designed a wearable sensor that can detect two key biomarkers of infection in human sweat, a significant step toward making it possible for users to receive early warnings of infections such as COVID-19 and influenza.

2 May 2022

Tracking BA.2.12.1 🦠 by partial ORF1ab gene 🧬 target failure (pOGTF)

Scientists from the United States have recently identified a novel approach to rapidly and accurately detect the omicron BA.2.12.1 sub-lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples.

2 May 2022

Polymerase Chain Reaction News and Research

Further Reading

Using PCR-based genotyping to detect SARS-CoV-2 delta-omicron coinfection

Prenatal exposure to SARS-CoV-2 raises risk of neurological disorders in infants

Outcomes of COVID-19 treatment with Paxlovid

Results indicate that Omicron infection induces low levels of neutralizing antibodies in immunocompetent individuals

Study assesses the efficacy and safety of lithium treatment in patients infected with severe SARS-CoV-2

Study identifies two new Omicron lineages associated with a resurgence in infections in South Africa

Potential indirect and direct effects of SARS-CoV-2 on pancreatic islets in patients who became hyperglycemic after COVID-19

Free SARS-CoV-2 spike protein fragments may trigger platelet activation and clot formation in COVID-19

Oral Nirmatrelvir's effects on long COVID symptoms

Exploring definitions related to COVID-19 infection and deaths

Evaluating immune protection after third and fourth doses of homologous and heterologous SARS-CoV-2 vaccines among kidney transplant recipients

Study suggests SARS-CoV-2 Omicron is as deadly as past variants

Pets living in households with COVID-19 are high likely to seroconvert and become ill

How a COVID support team mitigated SARS-CoV-2 transmission within a university community

SARS-CoV-2 inhibition mediated by cellular nucleic acid-binding protein

Study explores which occupations had the greatest risk of SARS-CoV-2 infection and how relative differences varied over the pandemic

Effectiveness of ChAdOx1-S COVID-19 booster vaccine

Prior SARS-CoV-2 infection provides substantial and sustained protection from Omicron hospitalization

Novel wearable sensor can detect two key biomarkers of infection in sweat

Tracking BA.2.12.1 🦠 by partial ORF1ab gene 🧬 target failure (pOGTF)

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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