Postherpetic Neuralgia News and Research

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Depomed expands patent portfolio around extended release gabapentin formulation technology

Depomed, Inc. announced today that it has received a Notice of Allowance from the U.S. Patent and Trademark Office for a U.S. patent application (No. 12/239,591) directed to pharmaceutical dosage forms that deliver the compound gabapentin via Depomed’s proprietary Acuform® gastric retentive drug delivery technology.

2 Feb 2010

Endo Pharmaceuticals' partners receive Paragraph IV Certification Notice regarding LIDODERM

Endo Pharmaceuticals announced today that its partners, Teikoku Seiyaku Co., Ltd. and Teikoku Pharma USA, Inc. have received a Paragraph IV Certification Notice from Watson Laboratories, Inc. advising of the filing of an Abbreviated New Drug Application (ANDA) for a generic version of LIDODERM® (lidocaine topical patch 5%).

20 Jan 2010

FDA approves NeurogesX's Qutenza patch for postherpetic neuralgia treatment

NeurogesX, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved Qutenza(TM) (capsaicin) 8% patch, the first and only product containing prescription strength capsaicin, for the management of neuropathic pain due to postherpetic neuralgia (PHN), the nerve pain which can follow shingles.

17 Nov 2009

Positive results from Depomed's Phase 3 clinical trial of DM-1796 for postherpetic neuralgia

Depomed, Inc. today announced top-line results from a Phase 3 clinical trial demonstrating DM-1796 (also referred to as gabapentin ER) achieved a statistically significant reduction in pain associated with postherpetic neuralgia (PHN) versus placebo using the baseline observation carried forward (BOCF) method required by FDA.

5 Oct 2009

New drug combination releives neuropathic pain and improves sleep

People who suffer from debilitating neuropathic pain may get more relief and sleep better by combining two commonly-prescribed drugs.

1 Oct 2009

Retigabine's Phase IIa clinical trial preliminary results announced

Valeant Pharmaceuticals International today announced preliminary results from its Phase IIa proof-of-concept clinical trial of retigabine for the treatment of pain associated with postherpetic neuralgia (PHN), a painful and common complication of shingles.

24 Aug 2009

Oxycodone effective against shingles pain

The painkiller oxycodone is effective at treating the acute pain of shingles, an illness that often causes severe pain which can become long-lasting and sometimes even permanent.

26 Mar 2009

Shingles vaccine for seniors gets the green light

A government advisory panel in the United States has given it's backing for a new vaccine against shingles.

26 Oct 2006

Important first step towards designing new therapies for shingles

A team of scientists at the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health (NIH), has identified a human protein that helps varicella-zoster virus, the cause of chickenpox and shingles, spread from cell to cell within the body.

20 Oct 2006

Treatment with intravenous and oral antiviral medications may help relieve nerve pain related to shingles

A small trial suggests that treatment with intravenous and oral antiviral medications may reduce the nerve pain that occurs following shingles, according to a study posted online today that will appear in the July 2006 print issue of Archives of Neurology.

9 May 2006

Computer program lets people with Trigeminal neuralgia diagnose themselves

Trigeminal neuralgia, or TN, is a disorder affecting the areas of the face where the trigeminal nerve's branches are distributed, including the lips, eyes, nose, scalp, forehead, and upper and lower jaws.

13 Apr 2006

Reduction in small-fiber nerves may underlie complex regional pain syndrome-I

Researchers at Massachusetts General Hospital (MGH) have found the first evidence of a physical abnormality underlying the chronic pain condition called reflex sympathetic dystrophy or complex regional pain syndrome-I (CRPS-I).

13 Feb 2006

Stronger version of chickenpox vaccine cuts incidence and severity of shingles in older adults

In one of the largest adult vaccine clinical trials ever, researchers have found that an experimental vaccine against shingles (zoster vaccine) prevented about half of cases of shingles--a painful nerve and skin infection--and dramatically reduced its severity and complications in vaccinated persons who got the disease. The findings appear in the June 2 issue of The New England Journal of Medicine.

1 Jun 2005

Chronic pain treatments more effective when taken together

People suffering from chronic, debilitating pain caused by nerve damage or disease report better pain relief at lower doses of a combined drug treatment than from either drug administered individually, a new Queen’s study funded by the Canadian Institutes of Health Research (CIHR) shows.

3 Apr 2005

Need for greater understanding of shingles

Results from a recent international survey reveal that most people are aware of herpes zoster -- more commonly known as shingles -- but do not truly understand the complexity of the condition or the potential impact it has on their overall health.

23 Feb 2005

Guideline evaluates treatments for postherpetic neuralgia

A new guideline from the American Academy of Neurology evaluates treatments for postherpetic neuralgia. The guideline is published in the September 28 issue of Neurology, the scientific journal of the American Academy of Neurology.

28 Sep 2004

Indicators identify shingles patients who have an increased risk of developing persistent pain

Researchers have recently confirmed a set of indicators that, alone and in combination, identify shingles patients who have an increased risk of developing persistent pain after the shingles rash heals. Results and implications of their study will be presented in the May 11 issue of Neurology, the scientific journal of the American Academy of Neurology.

10 May 2004