Potassium Channel News and Research

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CNIC researchers unravel complexities of Andersen-Tawil syndrome

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has made a breakthrough discovery in the understanding of cardiac arrhythmias by unraveling the complexities of Andersen-Tawil syndrome (ATS), an extremely rare inherited cardiac disorder.

10 Apr 2024

Genes dictate taste: Study finds genetic links to food preferences

Study reveals the significant impact of genetic variations on adult dietary preferences, highlighting the complex interplay between genetics and food choices.

13 Feb 2024

UCL researchers develop new gene therapy to cure severe childhood epilepsy

UCL researchers have developed a new gene therapy to cure a devastating form of childhood epilepsy, which a new study shows can significantly reduce seizures in mice.

14 Dec 2023

A novel drug reduces the monthly frequency of seizure in adults with focal epilepsy

The effect of a novel Kv7.2/Kv7.3 potassium channel opener XEN1101 in reducing monthly seizure frequency in adults.

11 Oct 2023

New drug shows promise for epilepsy patients with resistant seizures

In cases where standard therapies fail, a medication called XEN1101 reduces seizure frequency by more than 50% in some patients and sometimes eliminates them altogether, a new study shows.

9 Oct 2023

International report paves way for precision diabetes medicine breakthrough

Precision medicine for prevention, diagnosis, treatment, and prognosis for Diabetes.

9 Oct 2023

Study reveals a new potential treatment approach for glioblastoma

The discovery of a previously unknown molecular target has inspired what may become a therapeutic breakthrough for people with glioblastoma, the most common and aggressive brain cancer.

11 Sep 2023

Metrion Biosciences announces launch of Good Laboratory Practice (GLP) hERG Screening Service

Metrion Biosciences Limited, the specialist ion channel contract research and drug discovery company, today announced it has received notification from the UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) that the Company is now a member of the UK GLP (Good Laboratory Practice) Compliance Monitoring Programme, and is, therefore, able to offer GLP compliant hERG ion channel screening services to the global life sciences community.

From Metrion Biosciences Limited 7 Aug 2023

Metrion Biosciences expands senior leadership team with appointments of Dr Robert Kirby as COO and Dr Edward Stevens as CSO

Metrion Biosciences Limited (“Metrion”), is a specialist ion channel contract research and drug discovery company.

From Metrion Biosciences Limited 6 Jul 2023

Study sheds light on a possible pharmacological approach to treat cardiac arrhythmias

Scientists at Simon Fraser University (SFU) and the Lankenau Institute for Medical Research (LIMR) near Philadelphia have found that a drug discovered at SFU and patented several years ago may have potential lifesaving results in the treatment of conditions leading to sudden cardiac death.

10 May 2023

Study reveals new clues to the underlying cause of FXS symptoms

In Fragile X syndrome (FXS), the most common cause of autism, sensory signals from the outside world are integrated differently, causing them to be underrepresented by cortical pyramidal neurons in the brain.

17 Feb 2023

Researchers develop an artificial neuron closely mimicking the characteristics of a biological neuron

Researchers reported a conductance-based organic electrochemical neuron that mimicked biological signaling in neurons, especially activation/inactivation of their sodium and potassium channels.

16 Jan 2023

Researchers secure $20.5 million NIH grant to beat Alzheimer's disease and related dementias

A team of researchers at the University of Kentucky's Sanders-Brown Center on Aging has been awarded a $20.5 million grant from the National Institute on Aging of the National Institutes of Health.

2 Sep 2022

Single mutation in Kcnc3 gene causes learning deficits in mice

A single mutation in a gene, Kcnc3, which encodes a potassium channel in neurons, causes learning deficits in mice, UT Southwestern researchers report in a new study in PNAS.

29 Aug 2022

Study shows how microglia contribute to slowdown of neuron activity linked with Alzheimer’s

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience.

4 Aug 2022

Tokyo Tech researchers develop the first synthetic mechanosensitive potassium channel

Intrigued by the properties of ion channel proteins commonly observed in cells, Tokyo Tech researchers have developed the first synthetic mechanosensitive potassium channel using a newly developed aromatic fluorinated amphiphilic cyclophane.

15 Jul 2022

Study uncovers an over-looked mechanism that likely contributes to autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic condition that can lead to kidney failure and that has no cure.

13 Jul 2022

Study elucidates the molecular mechanisms of acetylcholine for learning and memory

Acetylcholine (ACh) is a neuromodulator with a central role in aversive learning-;rapid conditioning to unpleasant smell, taste, or touch.

28 Jun 2022

U-M researchers reveal how a mutated protein acts as risk factor in Parkinson’s disease

In about a fifth of the cases of Parkinson’s disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.

23 Jun 2022

Scientists discover 15 additional genetic mutations linked to KCNK9 imprinting syndrome

A collaborative team of scientists led by Mayo Clinic's Center for Individualized Medicine has discovered 15 additional genetic mutations in the KCNK9 gene that cause a neurodevelopmental syndrome.

21 Jun 2022