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Exploring the impact of soy isoflavones in prostate cancer therapy

The cellular mechanisms of soy isoflavones, genistein, daidzein, and equol.

23 Nov 2023

Numbing agent lidocaine may have cancer-fighting properties

Lidocaine-;often used as numbing agent for outpatient medical procedures-;activates certain bitter taste receptors through two unique mechanisms that result in cancer cell death, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

22 Nov 2023

Combined application of therapeutic viruses and nanomaterials to revolutionize cancer therapy

Using oncolytic viruses (OVs) in combination with nanomaterials as a novel approach to cancer treatment.

22 Nov 2023

Excessive diet soft drink consumption is associated with the occurrence of liver disease

The association between diet soft drink intake and metabolic dysfunction-associated steatotic liver disease (MASLD).

22 Nov 2023

Scientists uncover key to enhancing cancer-killing T cells

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known as exhaustion.

21 Nov 2023

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Pioneering epigenome editing company Tune Therapeutics has announced it is working on a new and potentially curative approach to treating chronic HBV infection.

20 Nov 2023

Researchers develop machine learning-based tool for assessment of shoulder function

A study published in Scientific Reports introduces a simple string-pulling task as a reliable method for assessing shoulder mobility in both animals and humans. This innovative approach, combined with machine learning, has the potential to revolutionize the diagnosis and monitoring of shoulder injuries, offering an affordable and accessible solution.

19 Nov 2023

Injectable grain-of-rice-sized glucose monitor could revolutionize diabetes management

The first glucose self-monitoring system created in 1970 weighed three pounds, was initially designed only for physicians' offices and needed a large drop of blood for a reading.

17 Nov 2023

Tackling Antimicrobial Resistance Together: A Conversation with Dr. Beverley Isherwood

An interview with Dr Beverley Isherwood.

16 Nov 2023

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

A subtype of CD8 T cells, which are classically known to promote immune system responses, may be in fact regulating the immune system by suppressing immune cells causing self-destructive responses leading to autoimmune disorders and organ graft rejection.

15 Nov 2023

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks.

15 Nov 2023

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Social, gendered variables may better explain observed sex disparities in adverse drug events

A new study out this week in the journal Social Science and Medicine proposes that social, gendered variables may better explain observed sex disparities in adverse drug events than sex-based biology.

14 Nov 2023

ATCC announces award from national institute of allergy and infectious diseases to support its preclinical services for biopharmaceutical product development

ATCC today announced that it has been awarded an Indefinite Delivery/Indefinite Quantity (IDIQ) contract.

From ATCC 13 Nov 2023

Exploring the use of psychedelics as novel treatments for psychiatric disorders

Psychedelic compounds such as psilocybin, a substance found in various mushroom species, are garnering more research support as novel treatments for psychiatric disorders, but questions remain concerning who they may help the most.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

Crown Bioscience, a global contract research organization (CRO) and JSR Life Sciences company, today announced the launch of its ground-breaking service offering, OrganoidXploreTM.

13 Nov 2023

AdvanCell reaches milestone as first prostate cancer patient dosed with 212Pb-ADVC001

AdvanCell, a radiopharmaceutical company developing a pipeline of Targeted Alpha Therapies for cancer patients, today announced the first patient was treated with 212Pb-ADVC001, a Targeted Alpha Therapy in development for the treatment of PSMA-positive metastatic Castration-Resistant Prostate Cancer (mCRPC).

13 Nov 2023

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

In this study, researchers harnessed crowdsourcing and open science to develop new antivirals against SARS-CoV-2, focusing on its main protease, Mpro. Their approach led to the discovery of potent compounds, including one with high efficacy in cell lines and cross-reactivity against various COVID-19 variants, demonstrating the potential of collaborative and transparent drug discovery in tackling global health crises.

12 Nov 2023

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer.

10 Nov 2023

Preclinical News and Research

Exploring the impact of soy isoflavones in prostate cancer therapy

Numbing agent lidocaine may have cancer-fighting properties

Combined application of therapeutic viruses and nanomaterials to revolutionize cancer therapy

Excessive diet soft drink consumption is associated with the occurrence of liver disease

Scientists uncover key to enhancing cancer-killing T cells

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Researchers develop machine learning-based tool for assessment of shoulder function

Injectable grain-of-rice-sized glucose monitor could revolutionize diabetes management

Tackling Antimicrobial Resistance Together: A Conversation with Dr. Beverley Isherwood

New vaccine promotes immune regulation that treats autoimmunity and prolongs transplant survival

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Cannabis shows promise in easing endometriosis pain, new research suggests

Social, gendered variables may better explain observed sex disparities in adverse drug events

ATCC announces award from national institute of allergy and infectious diseases to support its preclinical services for biopharmaceutical product development

Exploring the use of psychedelics as novel treatments for psychiatric disorders

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

Crown Bioscience launches large-scale organoid panel screening platform for accelerated preclinical oncology drug discovery

AdvanCell reaches milestone as first prostate cancer patient dosed with 212Pb-ADVC001

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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