Prediabetes News and Research

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Activation of chemical with ER-β may help reduce obesity by converting white fat to brown fat

New research, published online in The FASEB Journal, suggests that activation of a chemical called Beta-LGND2 by the estrogen receptor Beta (ER-Beta) reduces obesity and metabolic diseases in mice by converting bad fat (white fat) to good fat (brown fat).

17 Oct 2016

Researchers discover protein that plays role in onset of type 1 diabetes

A new study reveals a counterintuitive cellular strategy that may protect insulin-producing cells from destruction during type 1 diabetes.

31 Aug 2016

Lifestyle modification programs to prevent diabetes improve cardio-metabolic profiles

A new study by researchers at Emory's Rollins School of Public Health and the Centers for Disease Control and Prevention shows that lifestyle modification programs modeled on diabetes prevention programs trials not only achieved weight reduction, but also additional metabolic benefits -specifically, reductions in blood sugar, blood pressure, and cholesterol levels.

28 Jul 2016

Prevalence of global diabetes has been vastly underestimated, say Monash researchers

A landmark paper led by Monash University with partners in the UK and US suggests there may be more than 100 million people with diabetes globally than previously thought.

11 Jul 2016

Pioglitazone effective in diabetes patients with NASH

Pioglitazone may halt the progression of nonalcoholic steatohepatitis in patients with prediabetes or Type 2 diabetes, a randomised trial shows.

28 Jun 2016

Simple method may help predict type 2 diabetes risk in women with gestational diabetes

An international team of researchers has discovered a simple, accurate new way to predict which women with gestational diabetes will develop type 2 diabetes after delivery.

23 Jun 2016

Clinical trial finds pioglitazone drug safe and effective for NASH patients

Researchers have found that an existing diabetes drug can be used to halt progression of another disease that is a leading cause of liver transplants.

21 Jun 2016

Overtesting for HbA1C levels can increase risk of severe hypoglycemia

With a more-is-better mindset common in society, frequent commercials encouraging checks of glycated hemoglobin (HbA1C) levels, and ads for new diabetes medications to lower HbA1C in adults with Type 2 diabetes, Mayo Clinic researchers were not too surprised to find overtesting occurring.

7 Jun 2016

NR supplements can reduce diabetes-related complications in mice

A naturally occurring vitamin, nicotinamide riboside (NR), can lower blood sugar levels, reduce fatty liver, and prevent peripheral nerve damage in mouse models of prediabetes and type 2 diabetes (T2D), according to a new study by researchers at the University of Iowa and the Iowa City VA Health Care System.

27 May 2016

HbA1C test can effectively detect hidden diabetes among hyperglycemia patients

A retrospective review of medical records found the HbA1C test, commonly used to diagnose and manage diabetes, can effectively detect hidden disease among hospital patients with hyperglycemia, commonly known as high blood sugar.

24 May 2016

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects.

21 May 2016

Maintaining fitness wards off diabetes

Young adults who maintain good fitness levels into middle age reduce their risk of developing diabetes, irrespective of changes in their body mass index, show findings from the CARDIA study.

18 May 2016

NYU Stern innovation expert uncovers new link between diabetes and Alzheimer's disease

In a new paper published by The Journal of Alzheimer's Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer's disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer's disease.

13 Apr 2016

Infant daughters may show early signs of PCOS from mothers

The infant daughters of women with polycystic ovary syndrome (PCOS) show a higher level of an enzyme that activates testosterone and may be an early sign of developing the complex genetic disease, according to a new Northwestern Medicine study.

7 Apr 2016

Adding liraglutide to diet and exercise plan may help people lose weight, reduce diabetes risk

For people with prediabetes who are overweight or obese, adding 3.0 mg of liraglutide for three years to a diet and exercise plan may lead to major health improvements, new industry-sponsored research suggests. The results will be presented Monday, April 4, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

5 Apr 2016

Increased consumption of antibiotics in childhood may lead to adolescent prediabetes

Young children who take antibiotics may disrupt their gut's microbial ecosystem and be more likely to develop prediabetes in adolescence, new research from Greece reports. The study results will be presented in a poster Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

4 Apr 2016

Endocrine Society issues recommendations to improve care for people with diabetes

To provide integrated care for people who have diabetes and may be at risk of developing related medical complications, the U.S. health care system needs to continue building effective multidisciplinary care team models, according to new recommendations issued by the Endocrine Society today.

23 Mar 2016

Physicians miss opportunities for detection and management of people with prediabetes

Less than one-quarter of patients who met the criteria for prediabetes received drug or lifestyle modification treatment from their primary care physician, according to University of Florida researchers, who say the findings indicate physicians are missing opportunities for diabetes prevention.

9 Mar 2016

Community-based weight management program more effective in preventing prediabetes than self-initiated program

A new randomized controlled study conducted by Indiana University School of Medicine researchers and published online today in the American Journal of Public Health found that adults with prediabetes who followed a nationally-available weight management program with a prediabetes-specific component, Weight Watchers, lost significantly more weight and experienced better blood glucose control than those following a self-initiated program using supplemental counseling materials.

18 Feb 2016

Second-hand smoke exposure linked to larger waist, poorer cognition in children

Exposure to second-hand smoke is associated with a larger waist and poorer cognition in children, researchers say.

29 Jan 2016