Progenitor Cells News and Research

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A novel stem cell solution for preventing ischemia-induced amputations

Across the United States, about 2 million people are living with an amputation and another 185,000 amputations occur every year, according to the Amputee Coalition, a Washington DC-based support group.

19 Dec 2023

Patient-specific muscle models pave way for personalized neuromuscular therapies

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

19 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

Study reveals unexpected role of immune cells in early human lung development

Immune cells play an active and intimate role in directing the growth of human lung tissue during development, researchers find, revolutionizing our understanding of early lung development and the role of immune cells outside of immunity.

15 Dec 2023

Placental microparticles and their potential to predict and prevent neurodevelopmental disorders

For 30 years, Cheryl Rosenfeld has studied how biological information gets transferred from mothers to babies during pregnancy.

5 Dec 2023

Organoid model unveils secrets of the brain's dopaminergic system

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease.

5 Dec 2023

FDA clears Beckman Coulter Life Sciences AQUIOS STEM System for stem cell analysis

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, has received 510(k) clearance from the Food and Drug Administration (FDA) to distribute its popular AQUIOS STEM System in the United States.

From Beckman Coulter Life Sciences 4 Dec 2023

Temporal morphogen-driven neural induction spurs growth of expanded brain organoids with enhanced neuroepithelium formation

Researchers examinea the effects of temporal morphogen gradient during neural induction on the formation of brain organoids.

4 Dec 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Study reveals early role of SYNGAP1 gene in brain development

The gene SYNGAP1, the variants of which are top risk factors for Autism Spectrum Disorder (ASD), has previously unappreciated effects on the developing brain, according to a new study published in Nature Neuroscience.

9 Nov 2023

Research brings the prospect of injection-free treatment closer for people with diabetes

A University of Alberta team has developed a new step to improve the process for creating insulin-producing pancreatic cells from a patient's own stem cells, bringing the prospect of injection-free treatment closer for people with diabetes.

7 Nov 2023

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

Osteoarthritis may be treatable and reversible, new study shows

Current osteoarthritis treatment manages symptoms rather than addressing the underlying disease, but a new University of Adelaide study has shown the condition may be treatable and reversible.

31 Oct 2023

What are the effects of smoking cessation on vascular endothelial function?

The effects of smoking cessation on vascular endothelial function.

16 Oct 2023

3D printing crafts cerebral cortex tissues: A breakthrough for brain injury treatment

Researchers utilize 3D printing to craft cerebral cortex tissues with organized neurons, offering potential treatments for brain injuries. This novel technique prints neural progenitors in layer-by-layer sequences, aiming for accurate tissue restoration in damaged brains.

8 Oct 2023

Breakthrough technique could one day provide tailored repairs for people with brain injuries

A breakthrough technique developed by University of Oxford researchers could one day provide tailored repairs for those who suffer brain injuries.

4 Oct 2023

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

A recent review in the journal Immunity delves into the crucial role of dendritic cells (DCs) in shaping T-cell responses in cancer, highlighting their importance in both priming anti-tumor immunity and in ongoing immune interactions within tumors. The findings underscore the potential of DCs as key targets for next-generation cancer immunotherapies.

18 Sep 2023

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers develop CRISPR-human organoids-single-cell RNA sequencing system to identify developmental brain defects in autism.

18 Sep 2023

Progenitor Cells News and Research

A novel stem cell solution for preventing ischemia-induced amputations

Patient-specific muscle models pave way for personalized neuromuscular therapies

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Study reveals unexpected role of immune cells in early human lung development

Placental microparticles and their potential to predict and prevent neurodevelopmental disorders

Organoid model unveils secrets of the brain's dopaminergic system

FDA clears Beckman Coulter Life Sciences AQUIOS STEM System for stem cell analysis

Temporal morphogen-driven neural induction spurs growth of expanded brain organoids with enhanced neuroepithelium formation

UCI researchers discover gene critical for muscle repair

Study reveals early role of SYNGAP1 gene in brain development

Research brings the prospect of injection-free treatment closer for people with diabetes

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

Osteoarthritis may be treatable and reversible, new study shows

What are the effects of smoking cessation on vascular endothelial function?

3D printing crafts cerebral cortex tissues: A breakthrough for brain injury treatment

Breakthrough technique could one day provide tailored repairs for people with brain injuries

Unlocking the secret soldiers: How dendritic cells could revolutionize cancer immunotherapy

Single-cell screening of cerebral organoids to identify developmental defects in autism

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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