Progestin News and Research

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HRT not such a bad idea after all!

Older women struggling to cope with the symptoms of the menopause will be reassured by the latest research into hormone replacement therapy (HRT).

21 Jun 2007

Promoter hypermethylation is common in breast cancer

Cancer epidemiologists at the University at Buffalo have identified specific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation.

17 May 2007

Specific genes identified that are most likely to become cancer promoters when exposed to DNA promoter hypermethylation

Hypermethylation is a process that causes genes that promote normal cell growth to produce proteins that cause malignant behavior, or unregulated cell growth. Until now, data has been very limited regarding the mechanism and causes of hypermethylation, especially for hypermethylation in breast cancer.

15 May 2007

Steroidal hormones for contraception in women with sickle cell disease

Hormonal contraceptives are unlikely to predispose women to type 2 diabetes and appear to be safe for those with sickle cell anemia.

4 May 2007

Women who use estrogen hormone therapy before 65 reduce likelihood of Alzheimer's or dementia

Women who use hormone therapy before the age of 65 could cut their risk of developing Alzheimer's disease or dementia.

4 May 2007

Just to confuse you even more - HRT now linked to Alzheimer's!

To add to the utter confusion many women are feeling with regard to Hormone replacement therapy (HRT), new research is now suggesting HRT may reduce a woman's risk of Alzheimer's disease.

3 May 2007

Underlying causes of hot flashes

Many women in the menopausal transition experience hot flashes: unpredictable, sometimes disruptive, periods of intense heat in the upper torso, neck and face.

25 Apr 2007

Response to paper on ovarian cancer in the Million Women study

The Million Women Study (MWS) has reported new data on the risk of ovarian cancer in postmenopausal hormone users(1).

20 Apr 2007

Decrease in breast cancer incidence linked to drop in HRT

A special report in the April 19, 2007 edition of The New England Journal of Medicine concludes that the sharp decline in breast-cancer incidence in 2003, followed by a relative stabilization at a lower rater in 2004, is most likely related to the first report of the Women's Health Initiative (WHI).

19 Apr 2007

Drop in HRT use linked to decrease in breast cancer rates

According to the latest report the drop in the use of hormone replacement therapy (HRT) in mid-2002, following the results of the Women's Health Initiative study (WHI), is linked with a steep decline in new breast cancer diagnoses.

19 Apr 2007

Bayer Healthcare Pharmaceuticals launches in the U.S.

Bayer HealthCare Pharmaceuticals Inc. today announced its official U.S. launch. The new company incorporates the former Berlex Inc.into Bayer HealthCare Pharmaceuticals, as part of Bayer's acquisition of Schering AG, Germany, Berlex's former parent company.

5 Apr 2007

No apparent increase in coronary heart disease for women who initiate hormone therapy

Wyeth Pharmaceuticals, a division of Wyeth ( NYSE:WYE ) , provides comment on a re- analysis of pooled data from both hormone therapy arms of the Women's Health Initiative (WHI) Study published today in the Journal of the American Medical Association.

4 Apr 2007

Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause

Secondary analyses of findings from the Women's Health Initiative (WHI) suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause.

3 Apr 2007

Hormone patch could be safer than pills in relieving the symptoms of the menopause

According to new research by French scientists hormone skin patches and gels are far less likely than pills to cause dangerous blood clots.

26 Feb 2007

Risk of developing diabetes increasingly involved in decisions regarding HRT

Although doctors for years have "talked about the health effects of hormones on bones, breasts and women's hearts," diabetes has not been "part of the debate" until last week, when the North American Menopause Society in a revised position statement said that women taking hormone replacement therapy appear to be less likely to develop the disease, the Wall Street Journal reports.

7 Feb 2007

Ban called for on newer birth control pills

The advocacy group Public Citizen has filed a petition with the Food and Drug Administration (FDA) demanding that the sale of some of the newer birth control pills be banned.

6 Feb 2007

Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women

Aromatase inhibitors, a type of hormone therapy used to treat advanced breast cancer in postmenopausal women, result in a small but significant increase in overall survival when compared to other hormone treatments, according to a new systematic review of studies.

30 Jan 2007

Panel recommends FDA to not create specific effectiveness standard for oral contraceptive approvals

A panel of gynecologists, researchers and other medical experts on Wednesday at the end of a two-day meeting convened by FDA recommended the agency not set a specific standard of effectiveness for approval of oral contraceptives, the AP/Minneapolis Star Tribune reports.

28 Jan 2007

North American Menopause Society releases guidelines saying HRT beneficial for younger women

The North American Menopause Society on Thursday released a revised position statement that said the benefits of short-term hormone replacement therapy for treatment of menopausal women likely outweigh the risks for younger women, the Wall Street Journal reports.