Programmed Cell Death News and Research

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Scientists discover how B-cells in tumor cells promote a favorable immunotherapy response

The white blood cells are potent fighters that protect the body against foreign invaders, including pathogens and cancer cells. Scientists have found that the presence of B cells, which are powerhouses, in tumor cells, combat the disease from within.

16 Jan 2020

Mice study offers new insight on irritable bowel syndrome

Sometimes the end of an intestinal infection is just the beginning of more misery. Of those who contract traveler's diarrhea, for example, an unlucky few go on to develop irritable bowel syndrome (IBS), a chronic inflammation of the intestinal tract.

12 Jan 2020

Scientists discover how dying cells prevent dangerous immune reactions

Dying cells in the body can keep the immune system in check, thus preventing unwanted immune responses against the body's own tissues.

8 Jan 2020

Daily aspirin use may help prevent colorectal cancer

A new study has shown that regular use of aspirin may protect against heart disease, reduce colorectal tumor growth and prevent relapse.

7 Jan 2020

Aspirin’s benefits may extend beyond heart health to colorectal cancer treatment

The benefits of a daily aspirin may extend beyond heart health to colorectal cancer treatment, say City of Hope researchers who have found aspirin appears to reduce tumor growth and inhibit recurrence of the disease.

6 Jan 2020

Certain bacteria can override programmed cell death

Certain bacteria can override a defense mechanism of the immune system, so called programmed cell death, through inhibition of death effector molecules by their outer membranes components.

26 Dec 2019

p53 may play a more important role in kidney cancer than previously thought

The p53 gene, which researchers had thought was less relevant in kidney cancer, may play an important role after all – a discovery that could lead to new treatments.

20 Dec 2019

Scientist earns prestigious award for research into cell suicide

Apoptosis is a form of “cell suicide”, where a cell self-terminates, ideally as planned or programmed, enabling multi-cellular organisms to continue to live, develop and thrive.

4 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

Finding ways to stop cancer at its roots

Why do some cancers come back? Sometimes, a treatment can effectively eliminate cancer cells to undetectable levels, but, if the treatment stops, cancer may return.

7 Nov 2019

Cytoplasm of ruptured Xenopus frog eggs reorganizes into cell-like compartments, study shows

Can scrambled eggs unscramble themselves? Well, sort of.

6 Nov 2019

The Achilles heel of APC-mutated colon tumors identified

In almost all cases of colon cancer, a specific gene is mutated – this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further.

5 Nov 2019

Study describes a molecular strategy that helps prevent development of tumors in mice

The body's process for manufacturing fatty acids is regulated by the enzyme FASN. In normal cells, this is not a very active process - except occasionally in the liver and adipose tissue - since most of the fatty acids we need for cell maintenance are obtained from the diet.

4 Nov 2019

Study identifies a kinase as potential target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies.

31 Oct 2019

Study shows how Chlamydia bacteria enter human cells

Chlamydia are bacteria that can infect human and animal cells. Human health is particularly affected by Chlamydia pneumoniae (Cpn) and Chlamydia trachomatis.

31 Oct 2019

Novel, cost-effective method successfully identifies aggressive tumors

Researchers have developed a novel, cost-effective genomic method that can identify highly heterogenous tumors that are typically aggressive in nature.

30 Oct 2019

New cellular immunotherapy for cancers

A new study published in the journal Nature Communications on 22 October 2019 reports a new approach to cancer treatment that increases the immune capability of T lymphocytes against malignant cancers. This allows the T cells to successfully infiltrate and destroy these tumors. Animal trials have been completed and the researchers are planning clinical trials in human beings next.

26 Oct 2019