Programmed Cell Death News and Research

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What are the major findings of long COVID research?

Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.

17 Jan 2023

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

A new research paper was published in Oncotarget's Volume 13 on December 20, 2022, entitled, "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression."

6 Jan 2023

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies."

29 Dec 2022

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

A Japanese research group has become the first to reveal that the checkerboard-like arrangement of cells in the inner ear's organ of Corti is vital for hearing.

27 Dec 2022

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves.

23 Dec 2022

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers.

22 Dec 2022

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

HKUMed researchers at AIDS Institute, Department of Microbiology and Department of Surgery, School of Clinical Medicine, and School of Biomedical Sciences discover the role of an isoformic programmed cell death protein 1 (PD-1), namely Δ42PD-1, in suppressing the function of killer T cells, which is a type of immune cells essential for killing cancer cells among hepatocellular carcinoma (HCC) patients.

15 Dec 2022

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

In a new study, researchers developed two monkeypox (MPX) virus (MPXV) quadrivalent messenger ribonucleic acid (mRNA) vaccines, mRNA-A-lipid nanoparticle (LNP) and mRNA-B-LNP.

28 Nov 2022

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Mitochondria -; the organelles responsible for energy production in human cells -; were once free-living organisms that found their way into early eukaryotic cells over a billion years ago.

20 Oct 2022

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible.

12 Oct 2022

Cornell research offers insights into CRISPR RNA-guided Caspase system

New research from Cornell offers insights into a line of CRISPR systems, which could lead to promising antiviral and tissue engineering tools in animal and plants.

25 Aug 2022

Scientists identify new driver for rare type of liver cancer

Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Hebrew University in Jerusalem have identified in mice the cell of origin of combined liver/biliary duct carcinomas, a rare type of cancer of the liver.

19 Aug 2022

Programmed Cell Death News and Research

What are the major findings of long COVID research?

Research suggests potential therapeutic avenues to enhance PD-1 immune checkpoint sensitivity

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

Checkerboard-like arrangement of inner ear cells vital for hearing, research reveals

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

Study identifies Δ42PD-1 as novel therapeutic target for hepatocellular carcinoma immunotherapy

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Research shows how a very low dose of rhenium metal complex kills ovarian cancer cells

Cornell research offers insights into CRISPR RNA-guided Caspase system

Scientists identify new driver for rare type of liver cancer

Research may lead the way to a simpler treatment for cancer

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

Epigenetic changes prevent iron-associated programmed cell death in leukemia, research shows

Temporal changes in CD4 T-lymphocyte dynamics upon immunization against SARS-CoV-2 spike protein

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Study uncovers novel treatment for chromophobe renal cell carcinoma

New component of cell death process could play key role in infection-fighting strategy

MIT researchers design new sensor to distinguish between viral and bacterial pneumonia

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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