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New potential target for treating metastasized oral malignant melanoma in dogs

Scientists have shown that the biological molecule PD-L1 is a potential target for the treatment of metastasized oral malignant melanoma in dogs.

23 Apr 2021

Anti-diabetic drug phenformin may prompt stronger cancer-fighting activities

The anti-diabetic drug phenformin may prompt stronger cancer-fighting activities than its sister compound metformin, a finding that could have major implications for current and future clinical trials investigating both agents for their anti-cancer potential, according to researchers at Massachusetts General Hospital (MGH).

15 Apr 2021

High expression of cell death genes may increase risk of early death from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

5 Apr 2021

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Researchers have succeeded in revealing the arsenal used by protozoans of the genus Leishmania in human cells to make leishmaniasis more severe, especially in cases of the mucocutaneous variety of the disease, which can cause deformations in patients.

24 Mar 2021

Researchers explore nanotechnology’s potential to deliver synergistic therapeutics for COVID-19

A team of scientists reviewed the nanoencapsulation approaches of synergistic compounds (Lectins, Caffeine, Cocoa, Flavonoids, Quercetin) and the role of nanotechnology in addressing the COVID-19 pandemic.

19 Mar 2021

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

A new paper in the journal Life presents an early review of the viral factors involved in initiating and effecting apoptosis within infected cells.

8 Mar 2021

Scientists test the effect of natural product isolated from sea sponge on cancer cells

Scientists from Far Eastern Federal University together with Russian and German colleagues, continue studying antitumor compounds synthesized based on bioactive molecules isolated from a sea sponge.

1 Mar 2021

SARS-CoV-2 does not infect the entire body in the same way, finds study

COVID-19, the disease caused by the pandemic coronavirus SARS-CoV-2, is primarily regarded as a respiratory infection. Yet the virus has also become known for affecting other parts of the body in ways not as well understood, sometimes with longer-term consequences, such as heart arrhythmia, fatigue and "brain fog."

24 Feb 2021

Changes to gut microbiome help melanoma patients respond to immunotherapy

Statistical modeling developed by Oregon State University researchers has confirmed that changes to melanoma patients' gut microbiome led them to respond to a type of treatment capable of providing long-term benefit.

16 Feb 2021

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

In a new study, researchers discuss the use of simultaneous sequencing of both human and viral genes to better understand SARS-CoV-2's infection pathway.

15 Feb 2021

LMU researchers study T cell exhaustion

T lymphocytes, or T cells, are an important component of our immune system. They can recognize foreign proteins, so-called antigens, as peptide fragments - for instance, those derived from viruses or cancer cells.

13 Feb 2021

Major antioxidant in green tea may increase levels of natural anti-cancer protein

An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the "guardian of the genome" for its ability to repair DNA damage or destroy cancerous cells.

13 Feb 2021

New drug shows promise in treating pancreatic and breast cancers

ProAgio, a drug developed by Georgia State University biology professor Zhi-Ren Liu and his team, is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology.

9 Feb 2021

Subgenomic RNAs could help identify asymptomatic SARS-CoV-2 infection

Researchers report the association of subgenomic RNA (sgRNA) production, the structural differences between sgRNA variants, and clinical severity in 81 clinical specimens obtained from both asymptomatic and symptomatic individuals with SARS-CoV-2 infection.

9 Feb 2021

Programmed Cell Death News and Research

New potential target for treating metastasized oral malignant melanoma in dogs

Anti-diabetic drug phenformin may prompt stronger cancer-fighting activities

High expression of cell death genes may increase risk of early death from lung cancer

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Researchers explore nanotechnology’s potential to deliver synergistic therapeutics for COVID-19

Apoptosis is an important mediator of pathogenesis in animal coronavirus infection

Scientists test the effect of natural product isolated from sea sponge on cancer cells

SARS-CoV-2 does not infect the entire body in the same way, finds study

Changes to gut microbiome help melanoma patients respond to immunotherapy

Researchers study host and viral transcriptomes in tandem to shed light on SARS-CoV-2 infection

LMU researchers study T cell exhaustion

Major antioxidant in green tea may increase levels of natural anti-cancer protein

New drug shows promise in treating pancreatic and breast cancers

Subgenomic RNAs could help identify asymptomatic SARS-CoV-2 infection

POSTECH researchers discover mechanism behind intestinal epithelial lymphocyte differentiation

Tiny molecular motions are of key significance in modern anti-cancer drugs

New gold-nanoparticle probes for target identification of bioactive small molecules

Substances in tick saliva activate immune response-suppressing proteins in cattle

Researchers immunoengineer nanobead system for circulating tumor cell detection

Medicinal plant-derived compound destroys brain-eating amoeba in lab studies

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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