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New insights into the exacerbation of psoriasis through specific genetic defects

The inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.

27 Mar 2024

Biomechanical model simulates breast tumor growth

Scientists from Universidad Carlos III de Madrid (UC3M) and Johns Hopkins University (JHU), in the USA, have analyzed the growth of breast tumors from a biomechanical perspective and have created a computational model that simulates the invasion process of cancer cells, depending on the characteristics of the surrounding tissue and cell junctions, among other parameters.

21 Mar 2024

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Gastric cancer ranks among the most widespread diseases in Asian populations, with South Koreans experiencing the third-highest incidence globally in 2020, as reported by the International Agency for Research on Cancer.

21 Mar 2024

Lactate's role in driving cancer cachexia uncovered

Study highlights the significant role of lactate in promoting cancer cachexia via activation of the adipose-specific G-protein-coupled receptor 81 (GPR81), suggesting new therapeutic targets for this condition.

20 Mar 2024

Study reveals new strategy to improve and accelerate recovery from muscle injuries

Muscle injuries are common in the active population, and they cause the majority of player leaves in the world of sport.

19 Mar 2024

Unraveling the complexities of muscle repair in diabetes: A call for targeted research and therapies

Review outlines the impact of diabetes on skeletal muscle regeneration, highlighting the need for focused research and innovative therapies to tackle this growing health issue.

17 Mar 2024

Newly discovered adhesion GPCR mayo controls midgut development in Drosophila

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

15 Mar 2024

Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

The therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) from olive oil.

15 Mar 2024

Researchers develop an algorithm to identify high-risk precancerous lesions on the fallopian tubes

Researchers at the Johns Hopkins Kimmel Cancer Center and the Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine have developed an algorithm to identify high-risk precancerous lesions on the fallopian tubes.

14 Mar 2024

Researchers pioneer a novel approach to enhance diabetic wound healing

Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.

14 Mar 2024

Maternal obesity linked to liver cancer risk in offspring

Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern.

12 Mar 2024

Recent advances in injectable hydrogel-mediated myocardial infarction therapy

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Myocardial infarction (MI) triggers adverse remodeling mechanisms, thus leading to heart failure.

11 Mar 2024

Choosing the right fat for keto diets: Fish oil's significant role in cancer prevention

The anti-cancer efficacy of different oils consumed as a part of ketogenic diets (KDs).

11 Mar 2024

Researchers forge new path to combat viruses and cancers with helicase inhibitors

Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections-;and, alas, extraordinarily difficult to target with drugs.

9 Mar 2024

Study unravels FOXO1's influence on blood vessel development

The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for tackling age-related disorders.

9 Mar 2024

Researchers develop new algorithm to identify high-risk precancerous lesions on the fallopian tubes

6 Mar 2024

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Cervical cancer is among the most common malignancies affecting women worldwide. In 2020 alone, approximately 600,000 women were diagnosed with this disease, and over 314,000 died from it.

5 Mar 2024

Empathetic correction of misinformation can improve attitudes towards vaccination, study shows

An international study has shown for the first time how empathetic correction of misinformation among vaccine-hesitant patients can significantly improve attitudes towards vaccination – and potentially boost vaccine uptake.

4 Mar 2024

Scientists discover a key mechanism used by human herpesvirus 8 to induce cancer

Cleveland Clinic researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer.

1 Mar 2024

10 insights to tackle vaccine hesitancy driven by misinformation on social media

Effective population level vaccination campaigns are fundamental to public health. Countercampaigns, which are as old as the first vaccines, can disrupt uptake and threaten public health globally.

29 Feb 2024