Proliferation News and Research

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Exploring the role of the metabolic syndrome in individual mechanisms of liver fibrosis

Chronic liver injury results in the development of liver fibrosis in approximately 25% of individuals in response to diverse insults, and several aspects of the development of liver injury appear to be common to a variety of initiating factors.

31 Aug 2023

Mediterranean diet with a dairy twist shows promise in lowering heart disease risk

An 8-week study found that a Mediterranean diet supplemented with dairy foods altered specific gut bacteria and positively impacted systolic blood pressure in Australians at high risk of cardiovascular disease. The findings suggest that this MedDairy diet could be an effective strategy for reducing cardiovascular risks.

31 Aug 2023

Is drinking water hardness associated with cardiovascular disease mortality?

Total drinking water hardness can protect against cardiovascular disease mortality.

30 Aug 2023

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Researchers investigated whether bone marrow-derived cells contribute to colitis-associated colon cancer.

29 Aug 2023

Is alcohol exposure before and during pregnancy associated with reduced longitudinal fetal growth?

The association between exposure to alcohol in pregnancy and longitudinal growth.

29 Aug 2023

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

This recent study identifies new urinary biomarkers for detecting acute COVID-19 using spectroscopic analysis. The findings reveal that these biomarkers could offer valuable tools for early diagnosis, understanding the severity of the disease, and possibly contribute to endogenous immunological defense mechanisms against SARS-CoV-2.

29 Aug 2023

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Researchers explore how lifestyle changes like diet and physical activity can influence microRNA expression in Alzheimer's patients, potentially offering new therapeutic avenues. The study fills a research gap in understanding how such lifestyle modifications could affect molecular mechanisms implicated in Alzheimer’s disease.

28 Aug 2023

Study confirms the anti-cancer effects of Kencur extract

You may know it as an aromatic spice to add flavor to your dishes or as a soothing herbal remedy to use for upset stomachs, but researchers from Osaka Metropolitan University have uncovered promising findings that Kencur, a tropical plant in the ginger family native to Southeast Asia, possesses anti-cancer effects.

28 Aug 2023

Beyond traditional models: 3D bioprinted tumor microenvironment unlocks resistance insights

Researchers developed a three-dimensional (3D) biologically printed in vitro model of the breast cancer tumor microenvironment.

28 Aug 2023

Adolescence stress exposure impacts rodent brain development and behavior

Adolescence stress exposure in rodents can lead to reduced hippocampal cell proliferation, neuroplasticity, and cognitive impairments, as well as increased depressive-like behaviors. These effects may persist into adulthood but with variable impact.

27 Aug 2023

Study shows not all adrenal carcinoma patients need mitotane after surgery

After the complete tumor resection, not all patients with an adrenocortical carcinoma require the previous standard therapy Mitotane. Professors Martin Fassnacht and Massimo Terzolo show this in a clinical trial.

25 Aug 2023

KAUST researchers refute challenges to targeted cancer therapy

Drugs that inhibit a key protein should offer new targeted cancer therapy for leukemia and breast cancer.

24 Aug 2023

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

With around 90% of drugs failing to make it to market, the potential for improving efficiency within the drug development industry is clear. Drugs designed to combat cancers suffer similar rates of failure for many reasons.

23 Aug 2023

New kidney tissue model could help assess safety of immunotherapy drugs

A growing repertoire of cell and molecule-based immunotherapies is offering patients with indomitable cancers new hope by mobilizing their immune systems against tumor cells.

23 Aug 2023

Study unveils how Cutibacterium acnes boosts epidermal lipids for enhanced barrier protection

The role of Cutibacterium acnes in improving the skin's barrier function.

23 Aug 2023

Study explores lipid and metabolic alterations in HIV/TB co-infected patients

Researchers investigated the differential impact of HIV/tuberculosis co-infection on lipid and metabolic profiles.

23 Aug 2023

New insights into the pathogenic mechanisms of SLC29A3 disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

22 Aug 2023

Study shows link between regulatory T cells and anxiety, depression, Alzheimer's disease

Regulatory T cells-;work horses of the body's immune system-;may also stabilize mood, according to a study. Forkhead box P3 (Foxp3) is a transcription factor that controls the production of regulatory T cells (Tregs).

22 Aug 2023

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

The prevalence of colorectal cancer in people under the age of 50 has risen in recent decades. One suspected reason: the increasing rate of obesity and high-fat diets.

22 Aug 2023

New prognostic risk signature for kidney renal clear cell carcinoma identified

Announcing a new publication for Acta Materia Medica journal. Cuproptosis is a newly identified specific form of programmed cell death.

22 Aug 2023

Proliferation News and Research

Exploring the role of the metabolic syndrome in individual mechanisms of liver fibrosis

Mediterranean diet with a dairy twist shows promise in lowering heart disease risk

Is drinking water hardness associated with cardiovascular disease mortality?

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Is alcohol exposure before and during pregnancy associated with reduced longitudinal fetal growth?

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Study confirms the anti-cancer effects of Kencur extract

Beyond traditional models: 3D bioprinted tumor microenvironment unlocks resistance insights

Adolescence stress exposure impacts rodent brain development and behavior

Study shows not all adrenal carcinoma patients need mitotane after surgery

KAUST researchers refute challenges to targeted cancer therapy

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

New kidney tissue model could help assess safety of immunotherapy drugs

Study unveils how Cutibacterium acnes boosts epidermal lipids for enhanced barrier protection

Study explores lipid and metabolic alterations in HIV/TB co-infected patients

New insights into the pathogenic mechanisms of SLC29A3 disorders

Study shows link between regulatory T cells and anxiety, depression, Alzheimer's disease

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

New prognostic risk signature for kidney renal clear cell carcinoma identified

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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