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Critical Pharmaceuticals to develop hGH nasal spray

Critical Pharmaceuticals, the speciality pharmaceuticals company, today announced that it had secured a £1.5m translation award from the Wellcome Trust to develop a nasal spray of Human Growth Hormone (hGH) using its proprietary CriticalSorb technology as an alternative to injection.

15 Oct 2009

SwitchGear Genomics introduces high-throughput research tools for profiling biological pathway regulation

SwitchGear Genomics, Inc., a leading provider of products for studying regulatory elements in the human genome, today announced the availability of the first cost-effective, high-throughput research tools for screening transcriptional activation and repression in a number of key biological pathways.

14 Oct 2009

Lpath reports positive Phase 1 clinical trial results of iSONEP in wet-AMD patients

Lpath, Inc., the category leader in lipidomics-based therapeutics, reported positive summary results of its single-dose Phase 1 clinical trial of iSONEP™ in wet-AMD patients.

8 Oct 2009

Researchers identify tumor-suppressing genes to diagnose the phase of laryngeal cancer

Researchers at Henry Ford Hospital have identified tumor-suppressing genes that may provide a more accurate diagnosis of disease stage and survival for laryngeal cancer patients than current standards.

8 Oct 2009

Study identifies new genes associated with head and neck cancer

A Henry Ford Hospital study has identified 231 new genes associated with head and neck cancer, one of the most deadly cancers responsible for 2.1 percent of all cancer deaths in the United States.

5 Oct 2009

Research study reveals primary chemotherapy benefits

Initial chemotherapy alone after surgery is just as successful as initial radiation therapy for patients from whom a very malignant brain tumor (anaplastic glioma) was removed. With this treatment, the patients survive on average > 30 months without a recurrence. A study conducted by the Neurooncology Working Group of the German Cancer Society led by researchers from Heidelberg and Z-rich showed that patients in primary therapy benefit to the same extent from chemotherapy alone as from radiation alone.

3 Oct 2009

Grand Opportunity grant to pursue "whole-genome" sequencing of patients with autism

Children's Hospital Boston, with the Broad Institute and Harvard Medical School, has been awarded a Grand Opportunity grant from the National Institute of Mental Health as part of the federal stimulus package, to pursue "whole-genome" sequencing of patients with autism, using new technologies for rapid DNA sequencing to better understand autism's causes.

1 Oct 2009

Scarab Genomics releases new E. Coli strain

ScarabXpress is the latest strain in the multiple-deletion series (MDS) of Scarab Genomics Clean Genome® E. coli. Based on the MDS™42 strain, ScarabXpress T7lac contains a chromosomal copy of the T7 RNA polymerase gene expressed from a unique, tightly controlled lac promoter.

29 Sep 2009

Study: HBV genotype is not linked to hepatocellular carcinoma

Previous studies revealed that HBV genotypes as well as mutations in the core promoter, precore or HBx gene have been shown to have an association with the clinical outcome of liver disease, however, this is still controversial. It is likely that this depends on the HBV genotype distribution in certain region.

17 Sep 2009

Monoamine oxidases responsible for personality and behaviour

Antisocial and aggressive behaviours represent a widespread and expensive social problem. Recent research has convincingly shown that there is a strong interaction between genetic inheritance and environment for development of personality and behaviour.

14 Sep 2009

Heidelberg neuropathologists detect astrocytomas that can deactivate the "death receptor"

Malignant brain tumors often fail to respond to promising new medication. Researchers in Heidelberg have discovered a mechanism and a tumor marker for the development of this resistance. A "death receptor" can possibly provide information as to how great the chances of success are for chemotherapy. At the same time, it offers a new approach for promising brain tumor therapy.

2 Sep 2009

Research reveals the life-long detrimental impact of maternal smoking during pregnancy

A new study by researchers at the Keck School of Medicine of the University of Southern California (USC) has found that the life-long effects of maternal smoking during pregnancy may occur through specific changes in DNA patterns.

25 Aug 2009

Discovery of candidate tumor suppressor gene and potential biomarker for colorectal cancer

Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of the National Cancer Institute.

17 Jun 2009

New understanding of role ZBP1 gene plays in breast cancer

Scientists at Albert Einstein College of Medicine of Yeshiva University have discovered how a gene crucial in triggering the spread of breast cancer is turned on and off. The findings could help predict whether breast tumors will metastasize and also reveal potential drug targets for preventing metastasis.

12 May 2009

Proof-of-concept for a DNA-based therapeutic vaccination against chronic hepatitis C

The first-proof-of-concept for a DNA-based therapeutic vaccination against chronic hepatitis C was announced today at EASL 2009, the Annual Meeting of the European Association for the Study of the Liver in Copenhagen, Denmark.

23 Apr 2009

Using combinatorial libraries to engineer genetic circuits advances synthetic biology

Streamlining the construction of synthetic gene networks has led a team of Boston University researchers to develop a technique that couples libraries of diversified components with computer modeling to guide predictable gene network construction without the back and forth tweaking.

22 Apr 2009

Promoter News and Research

Critical Pharmaceuticals to develop hGH nasal spray

SwitchGear Genomics introduces high-throughput research tools for profiling biological pathway regulation

Lpath reports positive Phase 1 clinical trial results of iSONEP in wet-AMD patients

Researchers identify tumor-suppressing genes to diagnose the phase of laryngeal cancer

Study identifies new genes associated with head and neck cancer

Research study reveals primary chemotherapy benefits

Grand Opportunity grant to pursue "whole-genome" sequencing of patients with autism

Scarab Genomics releases new E. Coli strain

Study: HBV genotype is not linked to hepatocellular carcinoma

Monoamine oxidases responsible for personality and behaviour

Heidelberg neuropathologists detect astrocytomas that can deactivate the "death receptor"

Research reveals the life-long detrimental impact of maternal smoking during pregnancy

Discovery of candidate tumor suppressor gene and potential biomarker for colorectal cancer

New understanding of role ZBP1 gene plays in breast cancer

Proof-of-concept for a DNA-based therapeutic vaccination against chronic hepatitis C

Using combinatorial libraries to engineer genetic circuits advances synthetic biology

New nucleotide could revolutionize epigenetics

SIRT1 takes down tumors

Discovery of major new risk factor for melanoma in young women

Researchers create gene circuit that permits precise tuning of a gene's expression in a cell

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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