Prostatectomy News and Research

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Shift in prostate cancer Gleason grades from 1989 to 2001

Since the clinical introduction of PSA testing, there is reason to hypothesize that prostate cancer (CaP) Gleason grades may have shifted due to a variety of factors.

26 Jun 2006

Review identifies factors that influence patient treatment choice for localized prostate cancer

Variables that influence a patients' choice of treatment for localized prostate cancer (CaP) are identified in a literature review that is authored by Dr. Zeliadt and colleagues and appears in the on-line version of Cancer, 2006.

14 Jun 2006

Prostate adjustable continence therapy is a safe and effective treatment for post radical prostatectomy incontinence

Urinary incontinence after radical prostatectomy may affect 3-8% of patients and can have a significant negative impact on a patient's quality of life.

14 Jun 2006

Duloxetine proven effective for use in men with stress urinary incontinence after radical prostatectomy

Up to 33% of patients undergoing radical prostatectomy suffer from varying degrees of incontinence.

13 Jun 2006

Review identifies factors that influence patient treatment choice for localized prostate cancer

16 May 2006

Does age matter in selection of treatment for men with early-stage prostate cancer?

For men under the age 55 with localized prostate cancer, external beam radiation may be an effective alternative to both conservative and more invasive treatments, according to a new study.

8 May 2006

Combination of genetic mutation and viral infection may cause prostate cancer

Significant recent interest in the literature (JAMA 2006;295:1503, Lancet, epub) and by patients has arisen in response to a presentation given by Dr. Eric Klein of the Cleveland Clinic at the 2006 Prostate Cancer Symposium in San Francisco, February 24, 2006.

3 May 2006

Surgical robot makes prostate removal safe for obese men

The use of a robotic system could make surgery for prostate cancer an option for thousands of obese men who might otherwise be turned down, report researchers from the University of Chicago in the April 2006 issue of the journal Urology.

20 Apr 2006

Outcomes good for robotic radical prostatectomy in overweight and obese patients

Radical prostatectomy in overweight or obese men is a greater technical challenge than in thinner men. A laparoscopic or robotic-assisted laparoscopic prostatectomy (RLRP) might be easier.

18 Apr 2006

Review examines the management of radiotherapy induced rectourethal fistula

Rectourethral fistulas (RUF) are a challenging problem observed by urological and colorectal surgeons.

11 Apr 2006

Radical prostatectomy QoL outcomes can be obtained in single-surgeon practices

Most often urologists cite radical prostatectomy (RP) outcomes from large studies and high volume centers. However, these may not accurately reflect the outcomes of individual surgeons.

30 Mar 2006

Salvage radiation therapy for PSA recurrence following radical prostatectomy

Salvage radiation therapy to the prostatic fossa is often employed in patients with rising PSA after radical prostatectomy (RP). Interestingly, only 25% of men with rising PSA after RP have a positive prostatic fossa biopsy, yet 70% of men with a negative biopsy will have their PSA decline to undetectable levels following salvage external beam radiotherapy.

23 Mar 2006

Delayed prostate cancer intervention in low risk patients may not decrease ultimate chance for cure

A contemporary discussion exists whether patients with low-risk prostate cancer (CaP) are being overtreated with local treatment modalities. This is due to a combination of the older population affected and the slow doubling time of CaP.

23 Mar 2006

Prostate cancer detected on repeat biopsies have more favorable tumor characteristics but similar recurrence rates

Prostate cancer (CaP) detected on repeat biopsy may reflect smaller volume tumors and less aggressive biological and clinical disease.

17 Mar 2006

Study shows survival advantage for men treated with radical prostatectomy or radiation therapy compared to observation

A new study shows older men with early stage prostate cancer survive longer if they are treated versus not being treated in favor of the "watchful waiting" approach advocated by many physicians for older men with other health problems.

27 Feb 2006

Speed of PSA increase matters more than PSA level

In the largest study of its kind to date, Mayo Clinic researchers report that prostate specific antigen (PSA) kinetics, both velocity and doubling time, can be used to predict disease progression and likelihood of death after radical prostatectomy surgery, suggesting that this could be used to guide treatment decisions.

14 Nov 2005

New therapies for prostate cancer

A Dutch study suggested treating prostate cancer patients with higher doses of radiotherapy significantly improved patient outcome and treatment over a five-year period.

3 Nov 2005

Radical prostatectomy may be a safe option for the treatment of prostate cancer

Prostate cancer is the most common non-skin cancer in American men and the third most common cause of cancer death. In patients with localized disease, radical prostatectomy is associated with lower disease-specific mortality, lower rates of local progression and metastases, and higher overall survival compared with conservative management.

18 Oct 2005

Promising new treatment options for prostate cancer

Prostate cancer is the second leading cause of death among American men. It is estimated that one in six males will develop the disease during his lifetime. However, promising new treatment options have been developed to help combat this threatening disease.

9 Oct 2005

Development of aggressive forms of prostate cancer may be influenced by environmental effects that occur early in life

How heavy a man is at the time he is diagnosed with prostate cancer, as well as his history of weight gain, appear to play significant roles in how aggressive his cancer may become, say researchers at the University of Texas M. D. Anderson Cancer Center.

3 Oct 2005

Prostatectomy News and Research

Shift in prostate cancer Gleason grades from 1989 to 2001

Review identifies factors that influence patient treatment choice for localized prostate cancer

Prostate adjustable continence therapy is a safe and effective treatment for post radical prostatectomy incontinence

Duloxetine proven effective for use in men with stress urinary incontinence after radical prostatectomy

Review identifies factors that influence patient treatment choice for localized prostate cancer

Does age matter in selection of treatment for men with early-stage prostate cancer?

Combination of genetic mutation and viral infection may cause prostate cancer

Surgical robot makes prostate removal safe for obese men

Outcomes good for robotic radical prostatectomy in overweight and obese patients

Review examines the management of radiotherapy induced rectourethal fistula

Radical prostatectomy QoL outcomes can be obtained in single-surgeon practices

Salvage radiation therapy for PSA recurrence following radical prostatectomy

Delayed prostate cancer intervention in low risk patients may not decrease ultimate chance for cure

Prostate cancer detected on repeat biopsies have more favorable tumor characteristics but similar recurrence rates

Study shows survival advantage for men treated with radical prostatectomy or radiation therapy compared to observation

Speed of PSA increase matters more than PSA level

New therapies for prostate cancer

Radical prostatectomy may be a safe option for the treatment of prostate cancer

Promising new treatment options for prostate cancer

Development of aggressive forms of prostate cancer may be influenced by environmental effects that occur early in life

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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