Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

immatics, Roche enter into cancer vaccine and immunotherapy deal

immatics biotechnologies GmbH and Roche today announced a strategic research and development collaboration covering multiple cancer vaccines and immunotherapeutics.

13 Nov 2013

'Quitting cold turkey' can lead to mental decline, shows study

Can quitting drugs without treatment trigger a decline in mental health? That appears to be the case in an animal model of morphine addiction. Georgetown University Medical Center researchers say their observations suggest that managing morphine withdrawal could promote a healthier mental state in people.

13 Nov 2013

Researchers discover powerful mechanism that keeps white blood cells from going rogue

The immune system is a double-edged sword. While its primary role is to fight infections, it can also become overactive, leading to problems like allergies and autoimmune diseases.

13 Nov 2013

Novel discovery of RUNX3 gene provides new insights on defence mechanism against lung cancer

Novel discovery relating to the function of RUNX3 gene provides new insights on human defence mechanism against early stages of lung cancer development

13 Nov 2013

Study uncovers novel mechanism that helps govern regulated gene expression

A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression. The study was published on line in advance of print November 10 in the journal Nature Structural and Molecular Biology.

13 Nov 2013

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

FibroGen, Inc. (FibroGen), today announced that data from a China-based Phase 2 study of roxadustat (FG-4592), a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD), were presented in an oral session at the 2013 American Society of Nephrology (ASN) Kidney Week in Atlanta, Georgia.

13 Nov 2013

Researchers identify link between narrowed heart valves and special lipoprotein in blood

Researchers at the University of Copenhagen, Herlev Hospital and Rigshospitalet have identified a clear link between narrowed heart valves and a special lipoprotein in the blood. In the long term, the research may well help to prevent valvular heart disease.

13 Nov 2013

Researchers identify specific IRE1a inhibitor for rheumatoid arthritis treatment

Collaborating with researchers from the Northwestern University Feinberg School of Medicine in Chicago, a research team at Wayne State University's School of Medicine led by Kezhong Zhang, Ph.D., has contributed to an important discovery in the inflammatory stress mechanism and specific inhibitor for the treatment of rheumatoid arthritis.

13 Nov 2013

New view can give scientists better understanding of how antidepressants work in human brain

Research from Oregon Health & Science University's Vollum Institute, published in the current issue of Nature, is giving scientists a never-before-seen view of how nerve cells communicate with each other.

13 Nov 2013

Infection prevention: an interview with Dr. Robert Gorab, Chief Medical Officer, Hoag Orthopedic Institute

HOI has one of the lowest if not the lowest surgical readmission rate in the State of California. Our all-cause readmission rate is 3.3% and our joint replacement readmission was at 1.8% based on published CMS reports we received in September 2013.

12 Nov 2013

Revalesio to conduct RNS60 Phase IIa clinical trial in RRMS patients

Revalesio Corporation is pleased to announce a new collaboration with noted neurologist Dr. Roland Martin, Head of Neuroimmunology and MS Research at the Department of Neurology, University Hospital Zurich. Dr. Martin will be conducting a Phase IIa clinical trial of RNS60 in patients with relapsing-remitting multiple sclerosis.

12 Nov 2013

Nontoxic therapy shows encouraging results in blood samples from lupus patients

Northwestern Medicine- scientists have successfully tested a nontoxic therapy that suppresses Lupus in blood samples of people with the autoimmune disease.

12 Nov 2013

Researchers discover new pathway for treating allergic diseases

A collaboration among researchers in Israel and the United States has resulted in the discovery of a new pathway that has broad implications for treating allergic diseases - particularly eosinophil-associated disorders.

12 Nov 2013

Results announced for Phase 3B/4 study of RAPAMUNE in kidney transplant patients

Pfizer Inc. (NYSE:PFE) announced today top-line results from a Phase 3B/4 study of RAPAMUNE® (sirolimus) evaluating kidney transplant patients who transitioned from tacrolimus-based therapy (TAC) to RAPAMUNE® 3 to 5 months after transplant.

12 Nov 2013

Xin is muscle damage biomarker

Researchers at McMaster University have discovered a protein that is only detectable after muscle damage, and it may serve as a way to measure injury.

12 Nov 2013

Gene mutations responsible for persistent AD in African American children

Two specific genetic variations in people of African descent are responsible for persistent atopic dermatitis (AD), an itchy, inflammatory form of the skin disorder eczema. A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss-of-function mutations to Filaggrin-2 (FLG2), a gene that creates a protein responsible for retaining moisture and protecting the skin from environmental irritants, were associated with atopic dermatitis in African American children.

12 Nov 2013

Georgia University scientists identify cause of muscle weakness disease myasthenia gravis

An antibody to a protein critical to enabling the brain to talk to muscles has been identified as a cause of myasthenia gravis, researchers report.

12 Nov 2013

Pregnant women may transmit effects of stress to child by way of bacteria in vagina and placenta

Pregnant women may transmit the damaging effects of stress to their unborn child by way of the bacteria in their vagina and through the placenta, suggest new findings from two animal studies presented by researchers at the University of Pennsylvania at Neuroscience 2013, the annual meeting of the Society for Neuroscience.

12 Nov 2013

Researchers find zinc starves bacteria by preventing its uptake of essential metal

Australian researchers have found that zinc can 'starve' one of the world's most deadly bacteria by preventing its uptake of an essential metal.

11 Nov 2013

New biosensor could help doctors devise new ways to minimize brain damage during heart surgery

Johns Hopkins engineers and cardiology experts have teamed up to develop a fingernail-sized biosensor that could alert doctors when serious brain injury occurs during heart surgery. By doing so, the device could help doctors devise new ways to minimize brain damage or begin treatment more quickly.

11 Nov 2013

Protein News and Research

Further Reading

immatics, Roche enter into cancer vaccine and immunotherapy deal

'Quitting cold turkey' can lead to mental decline, shows study

Researchers discover powerful mechanism that keeps white blood cells from going rogue

Novel discovery of RUNX3 gene provides new insights on defence mechanism against lung cancer

Study uncovers novel mechanism that helps govern regulated gene expression

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

Researchers identify link between narrowed heart valves and special lipoprotein in blood

Researchers identify specific IRE1a inhibitor for rheumatoid arthritis treatment

New view can give scientists better understanding of how antidepressants work in human brain

Infection prevention: an interview with Dr. Robert Gorab, Chief Medical Officer, Hoag Orthopedic Institute

Revalesio to conduct RNS60 Phase IIa clinical trial in RRMS patients

Nontoxic therapy shows encouraging results in blood samples from lupus patients

Researchers discover new pathway for treating allergic diseases

Results announced for Phase 3B/4 study of RAPAMUNE in kidney transplant patients

Xin is muscle damage biomarker

Gene mutations responsible for persistent AD in African American children

Georgia University scientists identify cause of muscle weakness disease myasthenia gravis

Pregnant women may transmit effects of stress to child by way of bacteria in vagina and placenta

Researchers find zinc starves bacteria by preventing its uptake of essential metal

New biosensor could help doctors devise new ways to minimize brain damage during heart surgery

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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