Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Self-propagating aggregates key to Alzheimer's, other diseases

Two leading neurology researchers have proposed a theory that could unify scientists' thinking about several neurodegenerative diseases and suggest therapeutic strategies to combat them.

6 Sep 2013

Inner-ear dysfunction can increase hyperactivity, say researchers

Behavioral abnormalities are traditionally thought to originate in the brain. But a new study by researchers at Albert Einstein College of Medicine of Yeshiva University has found that inner-ear dysfunction can directly cause neurological changes that increase hyperactivity.

6 Sep 2013

Behavior problems in childhood may lead to inflammatory conditions later in life

Children with behavioral problems may be at risk of many chronic diseases in adulthood including heart disease, obesity, diabetes, as well as inflammatory illnesses (conditions which are caused by cell damage).

6 Sep 2013

Disease Twofer: Parkin Problem Leads To Parkinson’S And Impairs Response To TB

University of California, San Francisco researchers report that a key protein associated with Parkinson's disease also plays a major role in the destruction of the bacteria that cause tuberculosis.

5 Sep 2013

Many developing countries in Asia-Pacific region face twin burdens of under and overnutrition

Asia and the Pacific's drive for food security has focused too narrowly on quantity, with a surge in obesity and still high levels of malnutrition in some countries highlighting the need for a new approach, says a new Asian Development Bank study.

5 Sep 2013

World Bank Group, IHME reports to help policymakers tackle health issues facing countries

In the Middle East and North Africa, heart disease, stroke, and diabetes are causing a massive amount of premature death and disability. People in Latin America and the Caribbean are living longer on the whole, yet they face increasing threats from chronic diseases. Mortality has declined in many South Asian countries, yet the number of deaths by non-communicable diseases and self-harm has skyrocketed since 1990.

5 Sep 2013

Elan enrolls first patient dosing in phase 2a study of ELND005 in Down syndrome

Elan Corporation, plc (NYSE: ELN) announced today the first patient dosing in a Phase 2a study of ELND005 in Down syndrome. Study ELND005-DS201 will evaluate the safety and pharmacokinetics of 2 doses of ELND005 and placebo in young adults with Down syndrome without dementia, and will also include select cognitive and behavioural measures.

5 Sep 2013

Biologists discover quality check system for neurons

Biologists at the University of California, San Diego have identified a new component of the cellular mechanism by which humans and animals automatically check the quality of their nerve cells to assure they're working properly during development.

5 Sep 2013

Natural compound in broccoli helps reduce risk for skin cancer

With skin cancer emerging as one of the world's most prevalent forms of cancer, researchers are using every tool at their disposal to fight this disease. The tool of choice for Sally Dickinson, PhD? Broccoli.

5 Sep 2013

TSRI scientists discover isoform of angiomotin protein responsible for tumorigenesis

A team led by scientists from The Scripps Research Institute (TSRI) have shown that a protein once thought to inhibit the growth of tumors is instead required for initial tumor growth. The findings could point to a new approach to cancer treatment.

5 Sep 2013

Scientists develop new form of aspirin to cope with resistance

Scientists are reporting development of a new form of aspirin - taken daily by about 60 million people in the United States alone to reduce the risk of heart attack and stroke - that could extend aspirin's benefits to people who may not respond to the drug. Their advance toward coping with "aspirin resistance" appears in the journal ACS Nano.

5 Sep 2013

Stress-related protein genetically linked to acceleration of Alzheimer's disease

A stress-related protein genetically linked to depression, anxiety and other psychiatric disorders contributes to the acceleration of Alzheimer's disease, a new study led by researchers at the University of South Florida has found.

5 Sep 2013

Parkin protein plays key role in destruction of bacteria that cause tuberculosis

A protein at the center of Parkinson's disease research now also has been found to play a key role in causing the destruction of bacteria that cause tuberculosis, according to scientists led by UC San Francisco microbiologist and tuberculosis expert Jeffery Cox, PhD.

5 Sep 2013

Research findings raise hope for new heart therapies

Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University School of Medicine's Cardiovascular Research Center recently found hope in an unlikely source - stem cells in cortical, or compact, bone.

5 Sep 2013

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Affinium Pharmaceuticals announced today that it has initiated dosing in a Phase 1 intravenous clinical trial of its new antibiotic prodrug, AFN-1720. AFN-1720 is the prodrug of the active drug, AFN-1252.

5 Sep 2013

Sirt1 Protein, Not Calorie Restriction, Extends Life Span

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4 Sep 2013

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

The hepatitis C virus hijacks the body's immune system, leaving T cells unable to function. A new study in animal models suggests that blocking a protein that helps the virus thrive could restore immune function, allowing the body to fight infection. The work, led by teams at The Research Institute at Nationwide Children's Hospital and Emory University, was published online Aug. 26 in the Proceedings of the National Academy of Sciences.

4 Sep 2013

New mechanism operates specific protein in brain to bring delay in aging

Among scientists, the role of proteins called sirtuins in enhancing longevity has been hotly debated, driven by contradictory results from many different scientists. But new research at Washington University School of Medicine in St. Louis may settle the dispute.

4 Sep 2013

High sensitive troponin test may help doctors improve diagnosis in patients with heart attack

Abbott (NYSE: ABT) announced today promising preliminary results from a study presented at the ESC Congress 2013, suggesting that its high sensitive troponin test may help doctors improve the diagnosis and prognosis of patients presenting with symptoms of a heart attack.

4 Sep 2013

Research on long-lived proteins may lead to better understanding of molecular basis of aging

Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are replaced with new functional copies.

4 Sep 2013

Protein News and Research

Further Reading

Self-propagating aggregates key to Alzheimer's, other diseases

Inner-ear dysfunction can increase hyperactivity, say researchers

Behavior problems in childhood may lead to inflammatory conditions later in life

Disease Twofer: Parkin Problem Leads To Parkinson’S And Impairs Response To TB

Many developing countries in Asia-Pacific region face twin burdens of under and overnutrition

World Bank Group, IHME reports to help policymakers tackle health issues facing countries

Elan enrolls first patient dosing in phase 2a study of ELND005 in Down syndrome

Biologists discover quality check system for neurons

Natural compound in broccoli helps reduce risk for skin cancer

TSRI scientists discover isoform of angiomotin protein responsible for tumorigenesis

Scientists develop new form of aspirin to cope with resistance

Stress-related protein genetically linked to acceleration of Alzheimer's disease

Parkin protein plays key role in destruction of bacteria that cause tuberculosis

Research findings raise hope for new heart therapies

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Sirt1 Protein, Not Calorie Restriction, Extends Life Span

Blocking a protein helps virus to thrive and restore immune function to fight HCV infection

New mechanism operates specific protein in brain to bring delay in aging

High sensitive troponin test may help doctors improve diagnosis in patients with heart attack

Research on long-lived proteins may lead to better understanding of molecular basis of aging

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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