Protein Expression News and Research

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Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

Lung cancer is the leading cause of cancer deaths globally and a top cause of cancer deaths in the Military Health System.

15 Nov 2022

What are the current challenges and future directions of mRNA nanomedicine?

Researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations and future directions to improve the clinical efficacy of mRNA nanomedicine.

15 Nov 2022

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

Researchers investigated the change in the stability, antigenicity, and protein expression of the SARS-CoV-2 spike protein trimer using structure-directed mutagenesis to alter a cavity in the core of the spike protein.

14 Nov 2022

How mRNA vaccines work without an added adjuvant

In a recent study published in the Immunity journal, researchers explored the current knowledge of the mechanism employed by messenger ribonucleic acid (mRNA) vaccines to elicit innate immune activation.

13 Nov 2022

MicroRNAs can upregulate proteins in addition to downregulating protein production

microRNAs can play a role in cancer development and are thought to exclusively suppress protein expression in dividing cells, such as tumor cells.

10 Nov 2022

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes.

10 Nov 2022

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

In a recent study published in the journal Annals of Diagnostic Pathology, researchers in the United States evaluated the impact of coronavirus disease 2019 (COVID-19) on central nervous system (CNS) damage in Alzheimer's disease (AD).

7 Nov 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

In a new study, researchers assessed the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV envelope (E) proteins on human immunodeficiency virus type 1 (HIV-1) infectivity.

31 Oct 2022

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Researchers analyzed the phenotypes of the SARS-CoV-2 variants of concern (VOCs), the molecular responses to infections from these VOCs, and the evolving virus-host interactions using a comparative genomic and proteomic approach.

26 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

In a new study, researchers discussed the therapeutic potential of Panax ginseng for COVID-19 (coronavirus disease 2019)-induced neurological diseases.

14 Oct 2022

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

In a new study, researchers identified distinguishing immune features of coronavirus disease 2019 (COVID-19) in patients with late-resolving pulmonary fibrosis (LR COVID-PF) and early-resolving (ER COVID-PF).

4 Oct 2022

Protein Expression News and Research

Protein levels in lung tumors may predict prognosis, improve treatment and diagnostics

What are the current challenges and future directions of mRNA nanomedicine?

Structure-directed mutagenesis produces thermostable SARS-CoV-2 spike protein trimers with potential vaccine booster applications

How mRNA vaccines work without an added adjuvant

MicroRNAs can upregulate proteins in addition to downregulating protein production

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

COVID-19 amplifies damage to the central nervous system in Alzheimer's disease

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

Study reveals conserved and divergent host responses to infections with SARS-CoV-2 variants of concern

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

Multiomic comparison shows a reduction in circulating monocytes correlated with persistent post-COVID-19 pulmonary fibrosis

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

What is the impact of SARS-CoV-2 infection on semen parameters and sex hormones?

LncDACH1 may be a potential therapeutic target for pulmonary fibrosis

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

COVID-19's future is uncertain as infections increase and tracking decreases

What is the impact of COVID-19 treatments targeting intracellular Neu1?

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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