Protein Folding News and Research

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Novel motion capture-like technology for tracking how proteins fold into certain shape

In many modern animated movies, the trick to achieving realistic movements for individual characters and objects lies in motion-capture technology.

13 Feb 2018

Researchers use innovative method to screen kinases for cancer drug's effectiveness

In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude from cell surfaces like antennae and can activate cancer-related pathways in virtually all types of cancer when signaling molecules bind with them.

5 Feb 2018

Study finds new mechanism regulating giant protein essential for muscle and heart function

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III and Columbia University in New York have discovered an important mechanism in the regulation of a protein that plays an essential role in the function of skeletal muscle and the heart.

12 Jan 2018

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

The human protein, prohibitin, may be used by the virus to enter motor neurons and cause the neurological complications of hand, foot and mouth disease.

12 Jan 2018

Scientists discover specific mechanism of Zika virus-associated microcephaly

Epidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development of the cerebral cortex.

11 Dec 2017

Scientists invent new way of folding and protecting recombinant proteins

A team from the NUS Yong Loo Lin School of Medicine has invented a fundamentally new way of folding and protecting recombinant proteins.

13 Nov 2017

Researchers discover mechanism that corrects protein misfolding in plants

Various human nervous system diseases, such as amyotrophic lateral sclerosis (ALS), Alzheimer's, Huntington's, and Parkinson's diseases, are associated with the same basic disorder: the loss of nerve cells capacity to fold their proteins correctly, which causes protein aggregations that form "clumps" that end up generating the cell death.

25 Oct 2017

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

Researchers at the University of California San Diego have developed a genome-scale model that can accurately predict how E. coli bacteria respond to temperature changes and genetic mutations.

13 Oct 2017

New x-ray analysis methodology reveals structure of disordered protein

Scientists at The University of Notre Dame have shown that disordered proteins have a structure very close to what would be expected for a truly random structure using a novel X-ray scattering (SAXS) analysis methodology.

13 Oct 2017

MIT study sheds light on flu viruses' rapid evolution

Influenza viruses mutate rapidly, which is why flu vaccines have to be redesigned every year. A new study from MIT sheds light on just how these viruses evolve so quickly and offers a potential way to slow them down.

26 Sep 2017

Discovery reveals new role for endoplasmic reticulum-associated degradation

The discovery of a puddle of mouse urine seems like a strange scientific "eureka" moment. However, for one team of researchers, that's exactly what led to a new discovery.

20 Sep 2017

Newly-discovered mutation highlights complex genetic network that underpins blood disorder

Porphyrias, a group of eight known blood disorders, affect the body's molecular machinery for making heme, which is a component of the oxygen-transporting protein, hemoglobin. When heme binds with iron, it gives blood its hallmark red color.

7 Sep 2017

Unfolded protein response could be cause of metabolic disorders, say researchers

The cell's response to unfolded or misfolded proteins could be a cause, rather than a consequence, of metabolic disorders, report researchers at the Medical University of South Carolina in an article published online ahead of print on September 4, 2017 by Nature Structural & Molecular Biology.

4 Sep 2017

Penn study provides explanation for link between social isolation and greater risk of illness

Social isolation has been linked to a wide range of health problems, as well as a shorter lifespan in humans and other animals.

27 Jun 2017

Endoplasmic reticulum stress in the brain may cause non-alcoholic fatty liver disease

Disruptions in a protein folding process occurring in the brain, known as endoplasmic reticulum (ER) stress, may cause non-alcoholic fatty liver disease, independent of other factors. A research team at the George Washington University published their results in the Journal of Clinical Investigation Insight.

25 May 2017

Protein Folding News and Research

Novel motion capture-like technology for tracking how proteins fold into certain shape

Researchers use innovative method to screen kinases for cancer drug's effectiveness

Study finds new mechanism regulating giant protein essential for muscle and heart function

The Virus That Causes Hand, Foot and Mouth Disease May Use Human Protein to Aid Infection

Scientists discover specific mechanism of Zika virus-associated microcephaly

Scientists invent new way of folding and protecting recombinant proteins

Researchers discover mechanism that corrects protein misfolding in plants

New model predicts how E. coli bacteria respond to temperature changes, genetic mutations

New x-ray analysis methodology reveals structure of disordered protein

MIT study sheds light on flu viruses' rapid evolution

Discovery reveals new role for endoplasmic reticulum-associated degradation

Newly-discovered mutation highlights complex genetic network that underpins blood disorder

Unfolded protein response could be cause of metabolic disorders, say researchers

Penn study provides explanation for link between social isolation and greater risk of illness

Endoplasmic reticulum stress in the brain may cause non-alcoholic fatty liver disease

U-M research reveals important clues about invasion of polyomaviruses

Swiss researchers discover potential way to design new antibiotics

New study finds link between neural tube defects in infants and neurodegenerative diseases

Research findings could open new avenue to develop treatments for Alzheimer's disease

Study uncovers how effects of HSP90 protein can alter course of genetic diseases

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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